Search Results - "Bello, Alfonso E"

Efficacy and safety of intravenous tanezumab for the symptomatic treatment of osteoarthritis: 2 randomized controlled trials versus naproxen by Ekman, Evan F, Gimbel, Joseph S, Bello, Alfonso E, Smith, Michael D, Keller, David S, Annis, Karen M, Brown, Mark T, West, Christine R, Verburg, Kenneth M

“…Two studies evaluated efficacy and safety of tanezumab versus naproxen for treatment of knee or hip osteoarthritis (OA). Randomized controlled studies…”
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Celecoxib versus naproxen and diclofenac in osteoarthritis patients: SUCCESS-I Study by Singh, Gurkirpal, Fort, John G, Goldstein, Jay L, Levy, Roger A, Hanrahan, Patrick S, Bello, Alfonso E, Andrade-Ortega, Lilia, Wallemark, Carl, Agrawal, Naurang M, Eisen, Glenn M, Stenson, William F, Triadafilopoulos, George

“…To evaluate the efficacy and upper gastrointestinal (UGI) safety of celecoxib, compared with nonspecific nonsteroidal anti-inflammatory drugs (NSAIDs), among…”
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Cardiovascular Risk with Non-steroidal Anti-inflammatory Drugs: Clinical Implications by Bello, Alfonso E., Holt, Robert J.

“…In February 2014, the US Food and Drug Administration (FDA) convened an advisory committee meeting to discuss the accumulated data relating to the…”
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Collagen hydrolysate for the treatment of osteoarthritis and other joint disorders:a review of the literature by Bello, Alfonso E., Oesser, Steffen

“…ABSTRACT Background: There is a need for an effective treatment for the millions of people in the United States with osteoarthritis (OA), a degenerative joint…”
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Double-blind randomized trials of single-tablet ibuprofen/high-dose famotidine vs. ibuprofen alone for reduction of gastric and duodenal ulcers by Laine, Loren, Kivitz, Alan J, Bello, Alfonso E, Grahn, Amy Y, Schiff, Michael H, Taha, Ali S

“…We performed two 24-week double-blind trials (REDUCE-1 and -2 (Registration Endoscopic Studies to Determine Ulcer Formation of HZT-501 Compared with Ibuprofen:…”
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Recommendations for optimizing methotrexate treatment for patients with rheumatoid arthritis by Bello, Alfonso E, Perkins, Elizabeth L, Jay, Randy, Efthimiou, Petros

“…Methotrexate (MTX) remains the cornerstone therapy for patients with rheumatoid arthritis (RA), with well-established safety and efficacy profiles and support…”
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Characteristics, Comorbidities, and Potential Consequences of Uncontrolled Gout: An Insurance-Claims Database Study by Francis-Sedlak, Megan, LaMoreaux, Brian, Padnick-Silver, Lissa, Holt, Robert J., Bello, Alfonso E.

“…Introduction Gout is a common, progressive, systemic inflammatory arthritis caused by hyperuricemia. Current guidelines recommend that serum uric acid (sUA)…”
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Pooled analysis of tanezumab efficacy and safety with subgroup analyses of phase III clinical trials in patients with osteoarthritis pain of the knee or hip by Tive, Leslie, Bello, Alfonso E, Radin, David, Schnitzer, Thomas J, Nguyen, Ha, Brown, Mark T, West, Christine R

“…A pooled analysis was conducted to evaluate tanezumab efficacy and safety in patients with osteoarthritis (OA), including subgroup analyses of at-risk patients…”
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DUEXIS® (ibuprofen 800 mg, famotidine 26.6 mg): a new approach to gastroprotection for patients with chronic pain and inflammation who require treatment with a nonsteroidal anti-inflammatory drug by Bello, Alfonso E.

“…Chronic pain conditions affect at least 116 million US adults and more than one-third of adults worldwide. Nonsteroidal anti-inflammatory drugs (NSAIDs) are…”
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Effects of celecoxib and rofecoxib on blood pressure and edema in patients ≥65 years of age with systemic hypertension and osteoarthritis by Whelton, Andrew, White, William B, Bello, Alfonso E, Puma, Joseph A, Fort, John G

“…Concomitant use of nonsteroidal anti-inflammatory drugs (NSAIDs), including the cyclooxygenase-2 (COX-2) specific inhibitors, with antihypertensive medication…”
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One-year safety of ibuprofen/famotidine fixed combination versus ibuprofen alone: pooled analyses of two 24-week randomized, double-blind trials and a follow-on extension by Bello, Alfonso E., Grahn, Amy Y., Ball, Julie, Kent, Jeffrey D., Holt, Robert J.

“…Abstract Objective: To evaluate the safety of the fixed combination of ibuprofen and famotidine compared with ibuprofen alone from two 24-week, multicenter,…”
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One-year open-label safety evaluation of the fixed combination of ibuprofen and famotidine with a prospective analysis of dyspepsia by Bello, Alfonso E., Kent, Jeffrey D., Grahn, Amy Y., Ball, Julie, Holt, Robert J.

“…Abstract Objective: To assess the long-term safety of the single-tablet combination of ibuprofen 800 mg and famotidine 26.6 mg. Research design and methods: A…”
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Gastroprotective efficacy and safety of single-tablet ibuprofen/famotidine vs ibuprofen in older persons by Bello, Alfonso E, Kent, Jeffrey D, Holt, Robert J

“…A combination tablet of ibuprofen 800 mg and famotidine 26.6 mg given three times daily is effective for the treatment of rheumatoid arthritis and…”
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Cyclooxygenase-2--specific inhibitors and cardiorenal function: a randomized, controlled trial of celecoxib and rofecoxib in older hypertensive osteoarthritis patients by Whelton, A, Fort, J G, Puma, J A, Normandin, D, Bello, A E, Verburg, K M

“…Arthritis and hypertension are common comorbid conditions affecting elderly adults. Use of nonsteroidal anti-inflammatory drugs in patients treated with…”
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Onset and durability of pain relief in knee osteoarthritis: Pooled results from two placebo trials of naproxen/esomeprazole combination and celecoxib by Holt, Robert J, Fort, John G, Grahn, Amy Y, Kent, Jeffrey D, Bello, Alfonso E

“…To further characterize time-to-first pain relief, effect size, correlations between various outcome measures and durability of relief for single-tablet…”
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Long Term Safety of an NSAID With Built-in Gastroprotection for Treatment of Pain and Inflammation Related to Oa and RA: Comparative Results From Blinded and Open Label One Year Safety Trials of a Single-Tablet Combination of Ibuprofen-Famotidine by Goldstein, Jay L, Lakhanpal, Sharad, Cohen, Stanley B, Bello, Alfonso E, Ball, Julie, Grahn, Amy, Kivitz, Alan

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Risk of Upper Gastrointestinal Ulcers in Patients With Osteoarthritis Receiving Single-Tablet Ibuprofen/Famotidine Versus Ibuprofen Alone: Pooled Efficacy and Safety Analyses of Two Randomized, Double-Blind, Comparison Trials by Bello, Alfonso E., Kent, Jeffrey D., Grahn, Amy Y., Rice, Patricia, Holt, Robert J.

“…Background: Although anti-inflammatory doses of ibuprofen are very effective in treating the signs and symptoms of osteoarthritis (OA), they come with an…”
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Cyclooxygenase-2 specific inhibitors and upper gastrointestinal tolerability in patients with osteoarthritis receiving concomitant low dose aspirin: Pooled analysis of 2 trials by GOLDSTEIN, Jay L, BELLO, Alfonso E, SPALDING, William, SUH, Sandy, FORT, John G

“…To evaluate the relative gastrointestinal (GI) tolerability of celecoxib and rofecoxib in elderly hypertensive patients with osteoarthritis (OA) with or…”
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COX-2 Specific Inhibitors in the Management of Osteoarthritis of the Knee: A Placebo-Controlled, Randomized, Double-Blind Study by McKenna, Frank, Weaver, Arthur, Fiechtner, Justus J, Bello, Alfonso E, Fort, John G

“…COX-2 specific inhibitors have demonstrated significant safety advantages and comparable efficacy in osteoarthritis (OA) compared with conventional…”
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P-244: The effects of COX-2 specific inhibitors on edema and systolic blood pressure in elderly patients with osteoarthritis and treated hypertension: a pooled analysis on 1,902 patients by Puma, Joseph A., Bello, Alfonso E., Rodriguez, Jennifer J., Fort, John G.

“…Elderly patients with hypertension (HTN) and osteoarthritis (OA), who are already at high risk of cardiovascular events, may be particularly vulnerable to the…”
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