Hybrid imaging for detection of carcinoma of unknown primary: a preliminary comparison trial of whole-body PET/MRI versus PET/CT

Highlights • Both 18F-FDG PET/CT and 18F-FDG PET/MRI provide a comparable diagnostic ability for detection of primary cancer and metastases in CUP-syndrome. • PET/CT and PET/MRI showed comparably high lesion conspicuity and diagnostic confidence, offering superior assessment of pulmonary lesions in...

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Published in:European journal of radiology Vol. 85; no. 11; pp. 1941 - 1947
Main Authors: Ruhlmann, Verena, Ruhlmann, Marcus, Belllendorf, Alexander, Grueneisen, Johannes, Sawicki, Lino M, Grafe, Hong, Forsting, Michael, Bockisch, Andreas, Umutlu, Lale
Format: Journal Article
Language:English
Published: Ireland Elsevier B.V 01-11-2016
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Summary:Highlights • Both 18F-FDG PET/CT and 18F-FDG PET/MRI provide a comparable diagnostic ability for detection of primary cancer and metastases in CUP-syndrome. • PET/CT and PET/MRI showed comparably high lesion conspicuity and diagnostic confidence, offering superior assessment of pulmonary lesions in PET/CT and of cervical lesions in PET/MRI. • Considering the significantly lower dose of ionizing radiation, PET/MRI may serve as a powerful alternative to PET/CT in the future, particularly for therapy monitoring and/or surveillance considering the long-term cumulative dose.
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ISSN:0720-048X
1872-7727
DOI:10.1016/j.ejrad.2016.08.020