Search Results - "Bellefontaine, Nicole"
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Glutamate neurotransmission from leptin receptor cells is required for typical puberty and reproductive function in female mice
Published in eLife (15-07-2024)“…The hypothalamic ventral premammillary nucleus (PMv) is a glutamatergic nucleus essential for the metabolic control of reproduction. However, conditional…”
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Obesity and High-Fat Diet Induce Distinct Changes in Placental Gene Expression and Pregnancy Outcome
Published in Endocrinology (Philadelphia) (01-04-2018)“…Abstract Obese women are at high risk of pregnancy complications, including preeclampsia, miscarriage, preterm birth, stillbirth, and neonatal death. In the…”
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Long-term physiological alterations and recovery in a mouse model of separation associated with time-restricted feeding: a tool to study anorexia nervosa related consequences
Published in PloS one (04-08-2014)“…Anorexia nervosa is a primary psychiatric disorder, with non-negligible rates of mortality and morbidity. Some of the related alterations could participate in…”
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Nitric oxide as key mediator of neuron-to-neuron and endothelia-to-glia communication involved in the neuroendocrine control of reproduction
Published in Neuroendocrinology (01-01-2011)“…Nitric oxide (NO) is a peculiar chemical transmitter that freely diffuses through aqueous and lipid environments and plays a role in major aspects of brain…”
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Function-related structural plasticity of the GnRH system
Published in Frontiers in neuroendocrinology (01-07-2010)“…Abstract As the final common pathway for the central control of gonadotropin secretion, GnRH neurons are subjected to numerous regulatory homeostatic and…”
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Glutamate neurotransmission from leptin receptor cells is required for typical puberty and reproductive function in female mice
Published in eLife (15-07-2024)“…The hypothalamic ventral premammillary nucleus (PMv) is a glutamatergic nucleus essential for the metabolic control of reproduction. However, conditional…”
Get full text
Journal Article -
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Leptin-dependent neuronal NO signaling in the preoptic hypothalamus facilitates reproduction
Published in The Journal of clinical investigation (01-06-2014)“…The transition to puberty and adult fertility both require a minimum level of energy availability. The adipocyte-derived hormone leptin signals the long-term…”
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Minireview: Metabolic control of the reproductive physiology: Insights from genetic mouse models
Published in Hormones and behavior (01-06-2014)“…This article is part of a Special Issue Energy Balance. Over the past two decades, and in particular over the past 5–7 years, there has been a tremendous…”
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Kisspeptin-GPR54 signaling in mouse NO-synthesizing neurons participates in the hypothalamic control of ovulation
Published in The Journal of neuroscience (18-01-2012)“…Reproduction is controlled in the brain by a neural network that drives the secretion of gonadotropin-releasing hormone (GnRH). Various permissive homeostatic…”
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Sexually dimorphic distribution of Prokr2 neurons revealed by the Prokr2-Cre mouse model
Published in Brain Structure and Function (01-12-2017)“…Prokineticin receptor 2 (PROKR2) is predominantly expressed in the mammalian central nervous system. Loss-of-function mutations of PROKR2 in humans are…”
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Gonadotrophin-Releasing Hormone Nerve Terminals, Tanycytes and Neurohaemal Junction Remodelling in the Adult Median Eminence: Functional Consequences for Reproduction and Dynamic Role of Vascular Endothelial Cells
Published in Journal of neuroendocrinology (01-07-2010)“…Although coordinated actions of several areas within the hypothalamus are involved in the secretion of gonadotrophin‐releasing hormone (GnRH), the median…”
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Function-related structural plasticity of the GnRH system: a role for neuronal-glial-endothelial interactions
Published in Frontiers in neuroendocrinology (01-07-2010)“…As the final common pathway for the central control of gonadotropin secretion, GnRH neurons are subjected to numerous regulatory homeostatic and external…”
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Onset of sexual maturation in female mice as measured in behavior and fertility: Interactions of exposure to males, phytoestrogen content of diet, and ano-genital distance
Published in Physiology & behavior (27-02-2008)“…Abstract Age of puberty was examined in female mice through non-invasive behavioral and fertility measures, in relationship to ano-genital distance,…”
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Leptin-dependent neuronal NO signaling in the preoptic hypothalamus facilitates reproduction
Published in The Journal of clinical investigation (01-08-2014)Get full text
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PI3Kα inactivation in leptin receptor cells increases leptin sensitivity but disrupts growth and reproduction
Published in JCI insight (07-12-2017)“…The role of PI3K in leptin physiology has been difficult to determine due to its actions downstream of several metabolic cues, including insulin. Here, we used…”
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Phosphorylation of N-Methyl-d-Aspartic Acid Receptor-Associated Neuronal Nitric Oxide Synthase Depends on Estrogens and Modulates Hypothalamic Nitric Oxide Production during the Ovarian Cycle
Published in Endocrinology (Philadelphia) (01-06-2010)“…Within the preoptic region, nitric oxide (NO) production varies during the ovarian cycle and has the ability to impact hypothalamic reproductive function. One…”
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Gonadotrophin-releasing hormone nerve terminals, tanycytes and neurohaemal junction remodelling in the adult median eminence: functional consequences for reproduction and dynamic role of vascular endothelial cells: Neuronal-glial-endothelial interactions and GnRH release
Published in Journal of neuroendocrinology (01-07-2010)“…Although coordinated actions of several areas within the hypothalamus are involved in the secretion of gonadotrophin-releasing hormone (GnRH), the median…”
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The potential role of Neuropeptide Y Y5 receptor activation in the prolongation of lactational infertility induced by food restriction
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