Search Results - "Bellamy, C O C"

Functional Immune Anatomy of the Liver—As an Allograft by Demetris, A. J., Bellamy, C. O. C., Gandhi, C. R., Prost, S., Nakanuma, Y., Stolz, D. B.

“…The liver is an immunoregulatory organ in which a tolerogenic microenvironment mitigates the relative “strength” of local immune responses. Paradoxically,…”
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Working with Commercially Available Quantum Dots for Immunofluorescence on Tissue Sections by Prost, Sandrine, Kishen, Ria E B, Kluth, David C, Bellamy, Christopher O C

“…Quantum dots are semiconductor fluorescent nanocrystals that exhibit excellent characteristics compared with more commonly used organic fluorescent dyes. For…”
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Banff Fibrosis Study: Multicenter Visual Assessment and Computerized Analysis of Interstitial Fibrosis in Kidney Biopsies by Farris, A. B., Chan, S., Climenhaga, J., Adam, B., Bellamy, C. O. C., Serón, D., Colvin, R. B., Reeve, J., Mengel, M.

“…Increasing interstitial fibrosis (IF) in native and kidney transplant biopsies is associated with functional decline and serves as a clinical trial end point…”
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Choice of Illumination System & Fluorophore for Multiplex Immunofluorescence on FFPE Tissue Sections by Prost, Sandrine, Kishen, Ria E B, Kluth, David C, Bellamy, Christopher O C

“…The recent availability of novel dyes and alternative light sources to facilitate complex tissue immunofluorescence studies such as multiplex labelling has not…”
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A case of membranous nephropathy with microspherular deposits progressing to collapsing nephropathy and dialysis dependency, but with full recovery following immunosuppression by Sayer, Matthew, Pattle, Samuel, Phelan, Paul J, Bellamy, Christopher O C

“…Membranous nephropathy with microspherular deposits is a rare renal condition associated with sub-nephrotic or nephrotic-range proteinuria. We report a case…”
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Activation of thiazide-sensitive co-transport by angiotensin II in the cyp1a1-Ren2 hypertensive rat by Ashek, Ali, Menzies, Robert I, Mullins, Linda J, Bellamy, Christopher O C, Harmar, Anthony J, Kenyon, Christopher J, Flatman, Peter W, Mullins, John J, Bailey, Matthew A

“…Transgenic rats with inducible expression of the mouse Ren2 gene were used to elucidate mechanisms leading to the development of hypertension and renal injury…”
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Complement C4d immunohistochemistry in the assessment of liver allograft biopsy samples: Applications and pitfalls by Bellamy, Christopher O. C.

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C4d immunopositivity is uncommon in ABO-compatible liver allografts, but correlates partially with lymphocytotoxic antibody status by Bellamy, C O C, Herriot, M M, Harrison, D J, Bathgate, A J

“…Aims:  To determine whether C4d immunopositivity helps recognition of humoral rejection in dysfunctional liver allografts. Methods and results:  C4d…”
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Detection of viral hepatitis E in clinical liver biopsies by Prost, Sandrine, Crossan, Claire L, Dalton, Harry R, De Man, Robert A, Kamar, Nassim, Selves, Janick, Dhaliwal, Catharine, Scobie, Linda, Bellamy, Christopher O C

“…Aims To determine the relative utility of in‐situ testing for hepatitis E virus (HEV) RNA and paraffin‐section polymerase chain reaction (PCR) to diagnose HEV…”
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Acute Liver Injury Is Independent of B Cells or Immunoglobulin M by Richards, James A, Bucsaiova, Martina, Hesketh, Emily E, Ventre, Chiara, Henderson, Neil C, Simpson, Kenneth, Bellamy, Christopher O C, Howie, Sarah E M, Anderton, Stephen M, Hughes, Jeremy, Wigmore, Stephen J

“…Acute liver injury is a clinically important pathology and results in the release of Danger Associated Molecular Patterns, which initiate an immune response…”
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Additive effect of p53, p21 and Rb deletion in triple knockout primary hepatocytes by SHEAHAN, Sharon, BELLAMY, Christopher O. C, TREANOR, Louise, HARRISON, David J, PROST, Sandrine

“…Using Cre-Lox technology to inducibly delete Rb from wild-type, p21- and/or p53-deficient primary hepatocytes, we investigated the role of p53, p21 and pRb in…”
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The value of immunophenotyping hepatocellular adenomas: consecutive resections at one UK centre by Bellamy, Christopher O C, Maxwell, R Scott, Prost, Sandrine, Azodo, Ijeoma A, Powell, James J, Manning, Jonathan R

“…Aims:  To determine the utility of immunophenotyping for classification of hepatocellular adenomas resected at one Scottish centre. Methods and results:  This…”
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Letrozole as primary medical therapy for locally advanced and large operable breast cancer by DIXON, J. M, LOVE, C. D. B, BELLAMY, C. O. C, CAMERON, D. A, LEONARD, R. C. F, SMITH, H, MILLER, W. R

“…To investigate the efficacy of letrozole 2.5 mg and 10 mg used as primary neoadjuvant therapy for patients with locally advanced and large operable breast…”
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p53 and apoptosis by BELLAMY, C. O. C

“…Loss of fuction of the p53 tumour suppressor gene is a frequent and important event in the genesis or progession of many human malignancies. Loss of p53…”
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Mining liver rejection for archetypes: Gold or pyrites? by Bellamy, Christopher O.C., Zen, Yoh

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Angiotensin-converting Enzyme Is a Modifier of Hypertensive End Organ Damage by Liu, Xiaojun, Bellamy, Christopher O.C., Bailey, Matthew A., Mullins, Linda J., Dunbar, Donald R., Kenyon, Christopher J., Brooker, Gillian, Kantachuvesiri, Surasak, Maratou, Klio, Ashek, Ali, Clark, Allan F., Fleming, Stewart, Mullins, John J.

“…Severe forms of hypertension are characterized by high blood pressure combined with end organ damage. Through the development and refinement of a transgenic…”
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Tissue-Specific Immunopathology in Fatal COVID-19 by Dorward, David A, Russell, Clark D, Um, In Hwa, Elshani, Mustafa, Armstrong, Stuart D, Penrice-Randal, Rebekah, Millar, Tracey, Lerpiniere, Chris E B, Tagliavini, Giulia, Hartley, Catherine S, Randle, Nadine P, Gachanja, Naomi N, Potey, Philippe M D, Dong, Xiaofeng, Anderson, Alison M, Campbell, Victoria L, Duguid, Alasdair J, Al Qsous, Wael, BouHaidar, Ralph, Baillie, J Kenneth, Dhaliwal, Kevin, Wallace, William A, Bellamy, Christopher O C, Prost, Sandrine, Smith, Colin, Hiscox, Julian A, Harrison, David J, Lucas, Christopher D

“…In life-threatening coronavirus disease (COVID-19), corticosteroids reduce mortality, suggesting that immune responses have a causal role in death. Whether…”
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Endothelin Receptor Antagonism and Renin Inhibition as Treatment Options for Scleroderma Kidney by Dhaun, Neeraj, MBChB, MacIntyre, Iain M., MBChB, Bellamy, Christopher O.C., PhD, MBBS, FRCPath, Kluth, David C., PhD, MBBS

“…Scleroderma renal crisis (SRC) is an important complication of scleroderma associated with significant morbidity and mortality. Current treatment of patients…”
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Recurrent ANCA-Associated Vasculitis After Renal Transplantation by DHAUN, Neeraj, BLAKENEY, Jeremy, RICHARDS, Anna, BELLAMY, Christopher O. C, KLUTH, David C

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A Switch in the Mechanism of Hypertension in the Syndrome of Apparent Mineralocorticoid Excess by BAILEY, Matthew A, PATERSON, Janice M, HADOKE, Patrick W. F, WROBEL, Nicola, BELLAMY, Christopher O. C, BROWNSTEIN, David G, SECKL, Jonathan R, MULLINS, John J

“…The syndrome of apparent mineralocorticoid excess arises from nonfunctional mutations in 11beta-hydroxysteroid dehydrogenase type 2 (11betaHSD2), an enzyme…”
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