Search Results - "Bell, Sheila"

Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth by Guo, Minzhe, Du, Yina, Gokey, Jason J., Ray, Samriddha, Bell, Sheila M., Adam, Mike, Sudha, Parvathi, Perl, Anne Karina, Deshmukh, Hitesh, Potter, S. Steven, Whitsett, Jeffrey A., Xu, Yan

“…The respiratory system undergoes a diversity of structural, biochemical, and functional changes necessary for adaptation to air breathing at birth. To identify…”
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Delineating a conserved genetic cassette promoting outgrowth of body appendages by Lin, Congxing, Yin, Yan, Bell, Sheila M, Veith, G Michael, Chen, Hong, Huh, Sung-Ho, Ornitz, David M, Ma, Liang

“…The acquisition of the external genitalia allowed mammals to cope with terrestrial-specific reproductive needs for internal fertilization, and thus it…”
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PRDM3/16 regulate chromatin accessibility required for NKX2-1 mediated alveolar epithelial differentiation and function by He, Hua, Bell, Sheila M., Davis, Ashley Kuenzi, Zhao, Shuyang, Sridharan, Anusha, Na, Cheng-Lun, Guo, Minzhe, Xu, Yan, Snowball, John, Swarr, Daniel T., Zacharias, William J., Whitsett, Jeffrey A.

“…While the critical role of NKX2-1 and its transcriptional targets in lung morphogenesis and pulmonary epithelial cell differentiation is increasingly known,…”
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A census of the lung: CellCards from LungMAP by Sun, Xin, Perl, Anne-Karina, Li, Rongbo, Bell, Sheila M., Sajti, Eniko, Kalinichenko, Vladimir V., Kalin, Tanya V., Misra, Ravi S., Deshmukh, Hitesh, Clair, Geremy, Kyle, Jennifer, Crotty Alexander, Laura E., Masso-Silva, Jorge A., Kitzmiller, Joseph A., Wikenheiser-Brokamp, Kathryn A., Deutsch, Gail, Guo, Minzhe, Du, Yina, Morley, Michael P., Valdez, Michael J., Yu, Haoze V., Jin, Kang, Bardes, Eric E., Zepp, Jarod A., Neithamer, Terren, Basil, Maria C., Zacharias, William J., Verheyden, Jamie, Young, Randee, Bandyopadhyay, Gautam, Lin, Sara, Ansong, Charles, Adkins, Joshua, Salomonis, Nathan, Aronow, Bruce J., Xu, Yan, Pryhuber, Gloria, Whitsett, Jeff, Morrisey, Edward E.

“…The human lung plays vital roles in respiration, host defense, and basic physiology. Recent technological advancements such as single-cell RNA sequencing and…”
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Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium by Bell, Sheila M., Zhang, Liqian, Xu, Yan, Besnard, Valerie, Wert, Susan E., Shroyer, Noah, Whitsett, Jeffrey A.

“…Kruppel-like factor 5 (Klf5) is a transcription factor expressed by embryonic endodermal progenitors that form the lining of the gastrointestinal tract. A Klf5…”
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R-spondin 2 is required for normal laryngeal-tracheal, lung and limb morphogenesis by Bell, Sheila M, Schreiner, Claire M, Wert, Susan E, Mucenski, Michael L, Scott, William J, Whitsett, Jeffrey A

“…Herein, we demonstrate that Lrp6-mediated R-spondin 2 signaling through the canonical Wnt pathway is required for normal morphogenesis of the respiratory tract…”
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R-spondin2 signaling is required for oocyte-driven intercellular communication and follicular growth by De Cian, Marie-Cécile, Gregoire, Elodie P., Le Rolle, Morgane, Lachambre, Simon, Mondin, Magali, Bell, Sheila, Guigon, Céline J., Chassot, Anne-Amandine, Chaboissier, Marie-Christine

“…R-spondin2 (RSPO2) is a member of the R-spondin family, which are secreted activators of the WNT/β-catenin (CTNNB1) signaling pathway. In the mouse postnatal…”
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Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium by Bell, Sheila M., Zhang, Liqian, Mendell, Angela, Xu, Yan, Haitchi, Hans Michael, Lessard, James L., Whitsett, Jeffrey A.

“…Kruppel-like transcription factor 5 (Klf5) was detected in the developing and mature murine bladder urothelium. Herein we report a critical role of KLF5 in the…”
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Type V Collagen Controls the Initiation of Collagen Fibril Assembly by Wenstrup, Richard J., Florer, Jane B., Brunskill, Eric W., Bell, Sheila M., Chervoneva, Inna, Birk, David E.

“…Vertebrate collagen fibrils are heterotypically composed of a quantitatively major and minor fibril collagen. In non-cartilaginous tissues, type I collagen…”
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Kruppel-like factor 5 is required for perinatal lung morphogenesis and function by Wan, Huajing, Luo, Fengming, Wert, Susan E, Zhang, Liqian, Xu, Yan, Ikegami, Machiko, Maeda, Yutaka, Bell, Sheila M, Whitsett, Jeffrey A

“…The transition to air breathing after birth requires both anatomic and biochemical maturation of the lung. Lung morphogenesis is mediated by complex paracrine…”
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The Zinc Finger Transcription Factor Sp8 Regulates the Generation and Diversity of Olfactory Bulb Interneurons by Waclaw, Ronald R., Allen, Zegary J, Bell, Sheila M., Erdélyi, Ferenc, Szabó, Gábor, Potter, S. Steven, Campbell, Kenneth

“…The molecular mechanisms that regulate the production and diversity of olfactory bulb interneurons remain poorly understood. With the exception of the…”
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Airway Epithelial KIF3A Regulates Th2 Responses to Aeroallergens by Giridhar, Premkumar Vummidi, Bell, Sheila M, Sridharan, Anusha, Rajavelu, Priya, Kitzmiller, Joseph A, Na, Cheng-Lun, Kofron, Matthew, Brandt, Eric B, Ericksen, Mark, Naren, Anjaparavanda P, Moon, Changsuk, Khurana Hershey, Gurjit K, Whitsett, Jeffrey A

“…KIF3A, the gene encoding kinesin family member 3A, is a susceptibility gene locus associated with asthma; however, mechanisms by which KIF3A might influence…”
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EMC3 regulates mesenchymal cell survival via control of the mitotic spindle assembly by Tang, Xiaofang, Wei, Wei, Snowball, John M., Nakayasu, Ernesto S., Bell, Sheila M., Ansong, Charles, Lin, Xinhua, Whitsett, Jeffrey A.

“…Eukaryotic cells transit through the cell cycle to produce two daughter cells. Dysregulation of the cell cycle leads to cell death or tumorigenesis. Herein, we…”
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Forkhead Box m1 transcription factor is required for perinatal lung function by Kalin, Tanya V, Wang, I. Ching, Meliton, Lucille, Zhang, Yufang, Wert, Susan E, Ren, Xiaomeng, Snyder, Jonathan, Bell, Sheila M, Graf, Lloyd Jr, Whitsett, Jeffrey A, Kalinichenko, Vladimir V

“…The Forkhead Box m1 (Foxm1 or Foxm1b) transcription factor (previously called HFH-11B, Trident, Win, or MPP2) is an important positive regulator of DNA…”
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Nurse-led telephone outreach for a COVID-adapted suspected colorectal cancer pathway by Bell, Sheila E, Crawford, Jill, Gunn, Frances, Noble, Colin, Miller, Janice, Dunlop, Malcolm G, Maeda, Yasuko, Din, Farhat VN

“…Background: COVID-19 has brought about unprecedented challenges to healthcare services in the UK. The pandemic led to the cessation of colonoscopy and…”
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Sp8 Is Crucial for Limb Outgrowth and Neuropore Closure by Bell, Sheila M., Schreiner, Claire M., Waclaw, Ronald R., Campbell, Kenneth, Potter, S. Steven, Scott, William J.

“…In this report we describe the developmental expression and function of Sp8, a member of the Sp family of zinc finger transcription factors, and provide…”
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127 Kruppel-Like Factor 5 Controls Villus Formation and Initiation of Cytodifferentiation in the Embryonic Intestinal Epithelium by Bell, Sheila M, Zhang, Liqian, Xu, Yan, Besnard, Valerie, Wert, Susan E, Shroyer, Noah F, Whitsett, Jeffrey A

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Targeted disruption of the murine Nhe1 locus induces ataxia, growth retardation, and seizures by Bell, S M, Schreiner, C M, Schultheis, P J, Miller, M L, Evans, R L, Vorhees, C V, Shull, G E, Scott, W J

“…In most cells, the ubiquitously expressed Na+/H+ exchanger isoform 1 (NHE1) is thought to be a primary regulator of pH homeostasis, cell volume regulation, and…”
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Microarray analysis of murine limb bud ectoderm and mesoderm after exposure to cadmium or acetazolamide by Schreiner, Claire M., Bell, Sheila M., Scott Jr, William J.

“…BACKGROUND: A variety of drugs, environmental chemicals, and physical agents induce a common limb malformation in the offspring of pregnant mice exposed on day…”
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Cadmium-induced postaxial forelimb ectrodactyly: association with altered sonic hedgehog signaling by Scott, William J., Schreiner, Claire M., Goetz, John A., Robbins, David, Bell, Sheila M.

“…Administration of CdSO 4 to C57BL/6 mice at day 9.5 of gestation induces a high incidence of postaxial forelimb ectrodactyly in the offspring. We propose that…”
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