Search Results - "Bell, Ryan A V"

The beneficial role of proteolysis in skeletal muscle growth and stress adaptation by Bell, Ryan A V, Al-Khalaf, Mohammad, Megeney, Lynn A

“…Muscle atrophy derived from excessive proteolysis is a hallmark of numerous disease conditions. Accordingly, the negative consequences of skeletal muscle…”
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Caspase 3 cleavage of Pax7 inhibits self-renewal of satellite cells by Dick, Sarah A., Chang, Natasha C., Dumont, Nicolas A., Bell, Ryan A. V., Putinski, Charis, Kawabe, Yoichi, Litchfield, David W., Rudnicki, Michael A., Megeney, Lynn A.

“…Compensatory growth and regeneration of skeletal muscle is dependent on the resident stem cell population, satellite cells (SCs). Self-renewal and maintenance…”
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Evolution of caspase-mediated cell death and differentiation: twins separated at birth by Bell, Ryan A V, Megeney, Lynn A

“…The phenotypic and biochemical similarities between caspase-mediated apoptosis and cellular differentiation are striking. They include such diverse phenomenon…”
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Cancer cells use self-inflicted DNA breaks to evade growth limits imposed by genotoxic stress by Larsen, Brian D, Benada, Jan, Yung, Philip Yuk Kwong, Bell, Ryan A V, Pappas, George, Urban, Vaclav, Ahlskog, Johanna K, Kuo, Tia T, Janscak, Pavel, Megeney, Lynn A, Elsässer, Simon J, Bartek, Jiri, Sørensen, Claus S

“…Genotoxic therapy such as radiation serves as a frontline cancer treatment, yet acquired resistance that leads to tumor reoccurrence is frequent. We found that…”
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Purification and characterization of skeletal muscle pyruvate kinase from the hibernating ground squirrel, Urocitellus richardsonii: potential regulation by posttranslational modification during torpor by Bell, Ryan A. V., Storey, Kenneth B.

“…Ground squirrel torpor during winter hibernation is characterized by numerous physiological and biochemical changes, including alterations to fuel metabolism…”
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Stable Suppression of Lactate Dehydrogenase Activity during Anoxia in the Foot Muscle of Littorina littorea and the Potential Role of Acetylation as a Novel Posttranslational Regulatory Mechanism by Shahriari, Ali, Dawson, Neal J., Bell, Ryan A. V., Storey, Kenneth B.

“…The intertidal marine snail, Littorina littorea, has evolved to withstand extended bouts of oxygen deprivation brought about by changing tides or other…”
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Chromatin Reorganization during Myoblast Differentiation Involves the Caspase-Dependent Removal of SATB2 by Bell, Ryan A V, Al-Khalaf, Mohammad H, Brunette, Steve, Alsowaida, Dalal, Chu, Alphonse, Bandukwala, Hina, Dechant, Georg, Apostolova, Galina, Dilworth, F Jeffrey, Megeney, Lynn A

“…The induction of lineage-specific gene programs are strongly influenced by alterations in local chromatin architecture. However, key players that impact this…”
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Erratum to: The beneficial role of proteolysis in skeletal muscle growth and stress adaptation by Bell, Ryan A V, Al-Khalaf, Mohammad, Megeney, Lynn A

“…[This corrects the article DOI: 10.1186/s13395-016-0086-6.]…”
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Purification and Properties of White Muscle Lactate Dehydrogenase from the Anoxia-Tolerant Turtle, the Red-Eared Slider, Trachemys scripta elegans by Dawson, Neal J., Bell, Ryan A. V., Storey, Kenneth B.

“…Lactate dehydrogenase (LDH; E.C. 1.1.1.27) is a crucial enzyme involved in energy metabolism in muscle, facilitating the production of ATP via glycolysis…”
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Purification and properties of glyceraldehyde-3-phosphate dehydrogenase from the skeletal muscle of the hibernating ground squirrel, Ictidomys tridecemlineatus by Bell, Ryan A V, Smith, Jeffrey C, Storey, Kenneth B

“…Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from the skeletal muscle of euthermic and torpid Ictidomys tridecemlineatus was purified to electrophoretic…”
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Insights into the In Vivo Regulation of Glutamate Dehydrogenase from the Foot Muscle of an Estivating Land Snail by Bell, Ryan A. V., Dawson, Neal J., Storey, Kenneth B.

“…Land snails, Otala lactea, survive in seasonally hot and dry environments by entering a state of aerobic torpor called estivation. During estivation, snails…”
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Glucose-6-phosphate dehydrogenase regulation in the hepatopancreas of the anoxia-tolerant marine mollusc, Littorina littorea by Lama, Judeh L, Bell, Ryan A V, Storey, Kenneth B

“…Glucose-6-phosphate dehydrogenase (G6PDH) gates flux through the pentose phosphate pathway and is key to cellular antioxidant defense due to its role in…”
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Regulation of liver glutamate dehydrogenase by reversible phosphorylation in a hibernating mammal by Bell, Ryan A.V., Storey, Kenneth B.

“…Glutamate dehydrogenase (GDH) is a key enzyme that links amino acid and carbohydrate metabolism in cells. Regulation is likely most important when organisms…”
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Hexokinase regulation in the hepatopancreas and foot muscle of the anoxia-tolerant marine mollusc, Littorina littorea by Lama, Judeh L., Bell, Ryan A.V., Storey, Kenneth B.

“…Hexokinase from the hepatopancreas and foot muscle of Littorina littorea undergoes stable modification of its kinetic and structural properties in response to…”
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Novel detection method for chemiluminescence derived from the Kinase-Glo luminescent kinase assay platform: Advantages over traditional microplate luminometers by Bell, Ryan A.V., Storey, Kenneth B.

“…The efficacy of cellular signal transduction is of paramount importance for the proper functioning of a cell and an organism as a whole. Protein kinases are…”
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Stable suppression of skeletal muscle fructose-1,6-bisphosphatase during ground squirrel hibernation: Potential implications of reversible acetylation as a regulatory mechanism by Bell, Ryan A.V., Storey, Kenneth B.

“…Mammalian hibernation is a period that involves substantial metabolic change in order to promote survival in harsh conditions, with animals typically relying…”
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P06 : Posttranslational modification of glyceraldehyde-3-phosphate dehydrogenase from a hibernating mammal: Insight into cold-adaptation and structural diversity of a housekeeping enzyme by Bell, Ryan AV, Storey, Kenneth B.

“…Thirteen-lined ground squirrels, Spermophilus tridecemlineatus, endure cold winters by entering into hibernation; a period that entails extended bouts of…”
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P06 by Bell, Ryan AV, Storey, Kenneth B.

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150 Posttranslational modification of glyceraldehyde-3-phosphate dehydrogenase from a hibernating mammal: Insight into cold-adaptation and structural diversity of a housekeeping enzyme by Bell, Ryan A.V., Storey, Kenneth B.

“…13-lined ground squirrels, Spermophilus tridecemlineatus, endure cold winters by entering into hibernation; a period that entails extended bouts of aerobic…”
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