Search Results - "Bell, Philip B."

Parameters affecting the ex vivo cytotoxic drug sensitivity of human hematopoietic cells by Bosanquet, Andrew G, Burlton, Alison R, Bell, Philip B

“…The drug sensitivity of normal cells provides a baseline for determining the therapeutic index, and therefore the effectiveness, of cytotoxic drugs, yet little…”
Get more information

Learning Science in Informal Environments: People, Places, and Pursuits by Bell, Philip, Ed, Lewenstein, Bruce, Ed, Shouse, Andrew W., Ed, Feder, Michael A., Ed

“…Informal science is a burgeoning field that operates across a broad range of venues and envisages learning outcomes for individuals, schools, families, and…”
Get more information

Ex vivo therapeutic index by drug sensitivity assay using fresh human normal and tumor cells by Bosanquet, Andrew G, Bell, Philip B

“…Toxicity is a major deterrent to achieving substantial improvements in cancer management, since most anticancer drugs inadequately distinguish normal and…”
Get more information

Novel Ex Vivo Analysis of Nonclassical, Pleiotropic Drug Resistance and Collateral Sensitivity Induced by Therapy Provides a Rationale for Treatment Strategies in Chronic Lymphocytic Leukemia by Bosanquet, Andrew G., Bell, Philip B.

“…Extensive research into mechanisms of cytotoxic drug resistance and subsequent clinical trials of drug resistance modifiers have produced few encouraging…”
Get full text

Enhanced Ex vivo drug sensitivity testing of chronic lymphocytic leukaemia using refined DiSC assay methodology by Bosanquet, Andrew G., Bell, Philip B.

“…Ex vivo drug sensitivity testing is of considerable benefit in aiding the choice of optimum chemotherapy for leukaemia patients, especially when several…”
Get full text

Effect of interleukin-2 on CD95 (Fas/APO-1) expression in fresh chronic lymphocytic leukaemia and mantle cell lymphoma cells: relationship to ex vivo chemoresponse by Bosanquet, A G, Bell, P B, Rooney, N

“…Cells from B-cell chronic lymphocytic leukaemia (CLL) and mantle cell lymphoma (MCL) rarely express the CD95 (Fas/APO-1) antigen. Our aims were to determine…”
Get more information

Correlation of bcl-2 with P-glycoprotein expression in chronic lymphocytic leukaemia and other haematological neoplasms but of neither marker with ex vivo chemosensitivity or patient survival by Bosanquet, A G, Bell, P B, Burlton, A R, Amos, T A

“…We compared bcl-2 with P-glycoprotein expression (C494 and JSB1), and both with ex vivo chemosensitivity by Differential Staining Cytotoxicity (DiSC) assay (25…”
Get more information

CD79a detected by ZL7.4 separates chronic lymphocytic leukemia from mantle cell lymphoma in the leukemic phase by Bell, Philip B., Rooney, Nicholas, Bosanquet, Andrew G.

“…Both B‐cell chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL) are characterized by a lymphoproliferation of neoplastic CD5+ B‐cells, but an…”
Get full text