Search Results - "Bell, Jimmy"
-
1
Advanced body composition assessment: from body mass index to body composition profiling
Published in Journal of Investigative Medicine (01-06-2018)“…This paper gives a brief overview of common non-invasive techniques for body composition analysis and a more in-depth review of a body composition assessment…”
Get full text
Journal Article Book Review -
2
Feasibility of MR-Based Body Composition Analysis in Large Scale Population Studies
Published in PloS one (23-09-2016)“…Quantitative and accurate measurements of fat and muscle in the body are important for prevention and diagnosis of diseases related to obesity and muscle…”
Get full text
Journal Article -
3
The UK Biobank imaging enhancement of 100,000 participants: rationale, data collection, management and future directions
Published in Nature communications (26-05-2020)“…UK Biobank is a population-based cohort of half a million participants aged 40–69 years recruited between 2006 and 2010. In 2014, UK Biobank started the…”
Get full text
Journal Article -
4
Characterisation of liver fat in the UK Biobank cohort
Published in PloS one (27-02-2017)“…Non-alcoholic fatty liver disease and the risk of progression to steatohepatitis, cirrhosis and hepatocellular carcinoma have been identified as major public…”
Get full text
Journal Article -
5
Body Composition Profiling in the UK Biobank Imaging Study
Published in Obesity (Silver Spring, Md.) (01-11-2018)“…Objective This study aimed to investigate the value of imaging‐based multivariable body composition profiling by describing its association with coronary heart…”
Get full text
Journal Article -
6
The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism
Published in Nature communications (29-04-2014)“…Increased intake of dietary carbohydrate that is fermented in the colon by the microbiota has been reported to decrease body weight, although the mechanism…”
Get full text
Journal Article -
7
Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults
Published in Gut (01-11-2015)“…The colonic microbiota ferment dietary fibres, producing short chain fatty acids. Recent evidence suggests that the short chain fatty acid propionate may play…”
Get more information
Journal Article -
8
Differing genetic variants associated with liver fat and their contrasting relationships with cardiovascular diseases and cancer
Published in Journal of hepatology (01-12-2024)“…The mechanisms underlying the association of steatotic liver disease with cardiovascular and cancer outcomes are poorly understood. We aimed to use MRI-derived…”
Get full text
Journal Article -
9
Genetic architecture of 11 organ traits derived from abdominal MRI using deep learning
Published in eLife (15-06-2021)“…Cardiometabolic diseases are an increasing global health burden. While socioeconomic, environmental, behavioural, and genetic risk factors have been…”
Get full text
Journal Article -
10
Measurement of liver iron by magnetic resonance imaging in the UK Biobank population
Published in PloS one (21-12-2018)“…The burden of liver disease continues to increase in the UK, with liver cirrhosis reported to be the third most common cause of premature death. Iron overload,…”
Get full text
Journal Article -
11
Estimating the Effect of Liver and Pancreas Volume and Fat Content on Risk of Diabetes: A Mendelian Randomization Study
Published in Diabetes care (01-02-2022)“…Fat content and volume of liver and pancreas are associated with risk of diabetes in observational studies; whether these associations are causal is unknown…”
Get full text
Journal Article -
12
Abdominal imaging associates body composition with COVID-19 severity
Published in PloS one (13-04-2023)“…The main drivers of COVID-19 disease severity and the impact of COVID-19 on long-term health after recovery are yet to be fully understood. Medical imaging…”
Get full text
Journal Article -
13
Improving the accuracy of fatty liver index to reflect liver fat content with predictive regression modelling
Published in PloS one (13-09-2022)“…The fatty liver index (FLI) is frequently used as a non-invasive clinical marker for research, prognostic and diagnostic purposes. It is also used to stratify…”
Get full text
Journal Article -
14
MRI assessment of adipose tissue fatty acid composition in the UK Biobank and its association with diet and disease
Published in Obesity (Silver Spring, Md.) (01-09-2024)“…Objective This study aimed to assess the fatty acid (FA) composition of abdominal subcutaneous and visceral adipose tissue (ASAT and VAT, respectively) in the…”
Get full text
Journal Article -
15
LEAP2 changes with body mass and food intake in humans and mice
Published in The Journal of clinical investigation (01-09-2019)“…Acyl-ghrelin administration increases food intake, body weight, and blood glucose. In contrast, mice lacking ghrelin or ghrelin receptors (GHSRs) exhibit…”
Get full text
Journal Article -
16
Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Pilot Study
Published in Diabetes care (01-10-2016)“…Cannabidiol (CBD) and Δ(9)-tetrahydrocannabivarin (THCV) are nonpsychoactive phytocannabinoids affecting lipid and glucose metabolism in animal models. This…”
Get full text
Journal Article -
17
Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis
Published in Journal of hepatology (01-08-2020)“…MRI-based corrected T1 (cT1) is a non-invasive method to grade the severity of steatohepatitis and liver fibrosis. We aimed to identify genetic variants…”
Get full text
Journal Article -
18
Non-invasive means of measuring hepatic fat content
Published in World journal of gastroenterology : WJG (14-06-2008)“…Hepatic steatosis affects 20% to 30% of the general adult population in the western world. Currently, the technique of choice for determining hepatic fat…”
Get full text
Journal Article -
19
Dissociation between exercise-induced reduction in liver fat and changes in hepatic and peripheral glucose homoeostasis in obese patients with non-alcoholic fatty liver disease
Published in Clinical science (1979) (01-01-2016)“…Non-alcoholic fatty liver disease (NAFLD) is associated with multi-organ (hepatic, skeletal muscle, adipose tissue) insulin resistance (IR). Exercise is an…”
Get more information
Journal Article -
20
Obese patients after gastric bypass surgery have lower brain-hedonic responses to food than after gastric banding
Published in Gut (01-06-2014)“…Roux-en-Y gastric bypass (RYGB) has greater efficacy for weight loss in obese patients than gastric banding (BAND) surgery. We hypothesise that this may result…”
Get more information
Journal Article