Search Results - "Bell, G.I."

Resting beta-cells – A functional reserve? by Hara, M, Fowler, J.L, Bell, G.I, Philipson, L.H

“…Abstract Pancreatic beta-cells play a pivotal role to synthesize and secrete insulin, as the solo source of the body. Physical as well as functional loss of…”
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A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2 by Concannon, P, Yamagata, K, Bell, G.I, Ogata, M, Wang, Y.-Q, Ellsworth, D.L, Hanis, C.L, Stirling, B, Hinds, D, Lim, L.R, Spielman, R.S, Lindner, T, Chakraborty, R, Chen, X, Rietzsch, H, Boriraj, V.V, Cox, N.J, Wapelhorst, B, Omori, Y, Mereu, L.E, Iwasaki, N, Risch, N, Boerwinkle, E, Yang, Y, Shephard, J.M, Williams, S.R, Menzel, S, Schröder, H.-E, Gogolin-Ewens, K.J, Morrison, V.A, Xiang, K, Petzold, C, Schulze, J

“…Non-insulin-dependent (type 2) diabetes mellitus (NIDDM) is a common disorder of middle-aged individuals characterized by high blood glucose levels which, if…”
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Classification and nomenclature of somatostatin receptors by Hoyer, D., Bell, G.I., Berelowitz, M., Epelbaum, J., Feniuk, W., Humphrey, P.P.A., O'Carroll, A-M., Patel, Y.C., Schonbrunn, A., Taylor, J.E., Reisine, T.

“…There is considerable controversy about the classification and nomenclature of somatostatin receptors. To date, five distinct receptor genes have been cloned…”
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Structure and function of mammalian facilitative sugar transporters by BELL, G. I, BURANT, C. F, TAKEDA, J, GOULD, G. W

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Fructose transporter in human spermatozoa and small intestine is GLUT5 by BURANT, C. F, TAKEDA, J, BROT-LAROCHE, E, BELL, G. I, DAVIDSON, N. O

“…We recently reported that the glucose transporter isoform, GLUT5, is expressed on the brush border membrane of human small intestinal enterocytes (Davidson, N…”
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Sequence and functional characterization of a third inositol trisphosphate receptor subtype, IP3R-3, expressed in pancreatic islets, kidney, gastrointestinal tract, and other tissues by Blondel, O., Takeda, J., Janssen, H., Seino, S., Bell, G.I.

“…Inositol 1,4,5-trisphosphate (IP3) functions as a second messenger for many neurotransmitters, hormones and growth factors. It causes the release of Ca2+ from…”
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Cell adhesion. Competition between nonspecific repulsion and specific bonding by Bell, G.I., Dembo, M., Bongrand, P.

“…We develop a thermodynamic calculus for the modeling of cell adhesion. By means of this approach, we are able to compute the end results of competition between…”
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The cloned kappa opioid receptor couples to an N-type calcium current in undifferentiated PC-12 cells by Tallent, M, Dichter, M A, Bell, G I, Reisine, T

“…We have recently reported the cloning of a mouse kappa opioid receptor cDNA. Following transfection of the kappa receptor cDNA into COS-1 cells, a receptor is…”
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Glucokinase: structural analysis of a protein involved in susceptibility to diabetes by Pilkis, S J, Weber, I T, Harrison, R W, Bell, G I

“…The first step in the cellular metabolism of glucose in mammalian cells is the transfer of phosphate from ATP to the 6-hydroxyl group of the glucose molecule…”
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Missense glucokinase mutation in maturity-onset diabetes of the young and mutation screening in late-onset diabetes by Stoffel, M, Patel, P, Lo, Y-M.D, Hattersley, A.T, Lucassen, A.M, Page, R, Bell, J.I, Bell, G.I, Turner, R.C, Wainscoat, J.S

“…We describe a codon 299 mutation in the glucokinase gene in a British pedigree with maturity-onset diabetes of the young (MODY) resulting in a substitution of…”
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Localization of somatostatin (SRIF) SSTR-1, SSTR-2 and SSTR-3 receptor mRNA in rat brain by in situ hybridization by PEREZ, J, RIGO, M, KAUPMANN, K, BRUNS, C, YASUDA, K, BELL, G. I, LÜBBERT, H, HOYER, D

“…In situ hybridization histochemistry was performed to analyse the distribution of the messenger RNA (mRNA) of three putative somatostatin (SRIF) receptors in…”
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Human collagen, type II, alpha 1, (COL2A1) gene : VNTR polymorphism detected by gene amplification by WU, S, SEINO, S, BELL, G. I

“…Images…”
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Maturity onset diabetes of the young (MODY) by Fajans, S S, Bell, G I, Bowden, D W, Halter, J B, Polonsky, K S

“…MODY is a sub-type of NIDDM. It is characterized by an early age of onset and autosomal dominant mode of inheritance. These features, and the availability of…”
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brief perspective on insulin production by Steiner, D.F, Park, S.-Y, Støy, J, Philipson, L.H, Bell, G.I

“…The preeminent role of the beta cell is to manufacture, store and release insulin. The mature insulin molecule is composed of two polypeptide chains designated…”
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Mutations in the guinea pig preproglucagon gene are restricted to a specific portion of the prohormone sequence by Seino, S., Welsh, M., Bell, G.I., Chan, S.J., Steiner, D.F.

“…A cDNA clone encoding guinea pig preproglucagon has been isolated from a pancreatic cDNA library. The predicted amino acid sequence of proglucagon is highly…”
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Sequence of a cDNA coding for mouse manganese superoxide dismutase by Hallewell, R.A., Mullenbach, G.T., Stempien, M.M., Bell, G.I.

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Numerical calculation of dynamical friction in electron cooling systems, including magnetic field perturbations and finite time effects by Sobol, A V, Bruhwiler, D L, Bell, G I, Fedotov, A, Litvinenko, V

“…The orders-of-magnitude higher luminosities required by future electron-ion collider concepts require a dissipative force to counteract the numerous factors…”
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Polymorphism in exon 4a of the human GLUT4/ muscle-fat facilitative glucose transporter gene detected by SSCP by MURAOKA, A, SAKURA, H, KASUGA, M, SEINO, S, BELL, G. I, YAZAKI, Y, KADOWAKI, T, KIM, K, KISHIMOTO, M, AKANUMA, Y, BUSE, J. B, YASUDA, K

“…Images…”
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Molecular properties of somatostatin receptors by Reisine, T., Bell, G.I.

“…The neuropeptide somatostatin is widely distributed in the central nervous system and in peripheral tissues and may be involved in the regulation of a number…”
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Cloning and Functional Characterization of a Family of Human and Mouse Somatostatin Receptors Expressed in Brain, Gastrointestinal Tract, and Kidney by Yamada, Yuichiro, Post, Steven R., Wang, Kenneth, Tager, Howard S., Bell, Graeme I., Seino, Susumu

“…Somatostatin is a tetradecapeptide that is widely distributed in the body. It acts on multiple organs including brain, pituitary, gut, exocrine and endocrine…”
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