Search Results - "Bell, B Anthony"

Intra-cerebral injection of neuromyelitis optica immunoglobulin G and human complement produces neuromyelitis optica lesions in mice by Saadoun, Samira, Waters, Patrick, Bell, B. Anthony, Vincent, Angela, Verkman, A. S., Papadopoulos, Marios C.

“…Neuromyelitis optica is an inflammatory demyelinating disease of the central nervous system associated with autoantibodies against the glial water channel…”
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Neutrophil protease inhibition reduces neuromyelitis optica-immunoglobulin G-induced damage in mouse brain by Saadoun, Samira, Waters, Patrick, MacDonald, Claire, Bell, B. Anthony, Vincent, Angela, Verkman, A.S., Papadopoulos, Marios C.

“…Objective: Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the central nervous system associated with pathogenic autoantibodies against…”
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Diffusion tensor imaging discriminates between glioblastoma and cerebral metastases in vivo by Byrnes, Tiernan J. D., Barrick, Thomas R., Bell, B. Anthony, Clark, Chris A.

“…In a prospective study, patients with a radiologically proven brain tumour underwent diffusion tensor imaging (DTI) prior to definitive diagnosis and…”
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Serum angiogenic profile of patients with glioblastoma identifies distinct tumor subtypes and shows that TIMP-1 is a prognostic factor by Crocker, Matthew, Ashley, Sue, Giddings, Ian, Petrik, Vladimir, Hardcastle, Anthea, Aherne, Wynne, Pearson, Andy, Anthony Bell, B., Zacharoulis, Stergios, Papadopoulos, Marios C.

“…Angiogenesis plays a key role in glioblastoma biology and antiangiogenic agents are under clinical investigation with promising results. However, the…”
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Delays in treating patients with good grade subarachnoid haemorrhage in London by Lamb, Jonathan N., Crocker, Matthew, Tait, Matthew J., Anthony Bell, B., Papadopoulos, Marios C.

“…Background and purpose. Spontaneous aneurysmal subarachnoid haemorrhage (SAH) is managed as a neurosurgical priority with guidelines and published literature…”
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Magnetic resonance neurography studies of the median nerve before and after carpal tunnel decompression by CUDLIP, Simon A, HOWE, Franklyn A, CLIFTON, Andrew, SCHWARTZ, Martin S, BELL, B. Anthony

“…Recently developed novel MR protocols called MR neurography, which feature conspicuity for nerve, have been shown to demonstrate signal change and altered…”
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Monitoring of Spinal Cord Perfusion Pressure in Acute Spinal Cord Injury: Initial Findings of the Injured Spinal Cord Pressure Evaluation Study by Werndle, Melissa C, Saadoun, Samira, Phang, Isaac, Czosnyka, Marek, Varsos, Georgios V, Czosnyka, Zofia H, Smielewski, Peter, Jamous, Ali, Bell, B Anthony, Zoumprouli, Argyro, Papadopoulos, Marios C

“…OBJECTIVES:To develop a technique for continuously monitoring intraspinal pressure at the injury site (intraspinal pressure) after traumatic spinal cord…”
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Water movements in the brain: role of aquaporins by Tait, Matthew J, Saadoun, Samira, Bell, B. Anthony, Papadopoulos, Marios C

“…About 80% of the brain is water. This review discusses the importance of the three brain water-channel proteins (AQP1, AQP4, AQP9) in brain physiology. AQP1 is…”
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Opportunities and dangers for neurosurgery in the current NHS by Bell, B. Anthony

“…The NHS is entering a third decade of administrative turbulence and cost pressures and many view the new NHS structure and systems as complex and confusing…”
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The clinical value of early postoperative MRI after lumbar spine surgery by Crocker, Matthew, Jones, Timothy L., Rich, Philip, Bell, B. Anthony, Papadopoulos, Marios C.

“…Introduction. MRI scanning has historically been considered difficult to interpret in the early period following lumbar spine surgery, and hence of limited…”
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Brain tumor classification using the diffusion tensor image segmentation (D-SEG) technique by Jones, Timothy L, Byrnes, Tiernan J, Yang, Guang, Howe, Franklyn A, Bell, B Anthony, Barrick, Thomas R

“…There is an increasing demand for noninvasive brain tumor biomarkers to guide surgery and subsequent oncotherapy. We present a novel whole-brain diffusion…”
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Intraspinal pressure and spinal cord perfusion pressure after spinal cord injury: an observational study by Varsos, Georgios V, Werndle, Melissa C, Czosnyka, Zofia H, Smielewski, Peter, Kolias, Angelos G, Phang, Isaac, Saadoun, Samira, Bell, B Anthony, Zoumprouli, Argyro, Papadopoulos, Marios C, Czosnyka, Marek

“…In contrast to intracranial pressure (ICP) in traumatic brain injury (TBI), intraspinal pressure (ISP) after traumatic spinal cord injury (TSCI) has not…”
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Greatly improved neurological outcome after spinal cord compression injury in AQP4-deficient mice by Saadoun, Samira, Bell, B. Anthony, Verkman, A. S., Papadopoulos, Marios C.

“…Aquaporin-4 (AQP4) is a water channel protein expressed in astrocytes throughout the CNS. In brain, AQP4 facilitates water balance and glial scar formation,…”
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Tri-partite complex for axonal transport drug delivery achieves pharmacological effect by Filler, Aaron G, Whiteside, Garth T, Bacon, Mark, Frederickson, Martyn, Howe, Franklyn A, Rabinowitz, Miri D, Sokoloff, Alan J, Deacon, Terrence W, Abell, Chris, Munglani, Raj, Griffiths, John R, Bell, B Anthony, Lever, Andrew M L

“…Targeted delivery of pharmaceutical agents into selected populations of CNS (Central Nervous System) neurons is an extremely compelling goal. Currently,…”
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Measurement of Intraspinal Pressure After Spinal Cord Injury: Technical Note from the Injured Spinal Cord Pressure Evaluation Study by Werndle, Melissa C, Saadoun, Samira, Phang, Isaac, Czosnyka, Marek, Varsos, Georgios, Czosnyka, Zofia, Smielewski, Peter, Jamous, Ali, Bell, B Anthony, Zoumprouli, Argyro, Papadopoulos, Marios C

“…Intracranial pressure (ICP) is routinely measured in patients with severe traumatic brain injury (TBI). We describe a novel technique that allowed us to…”
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White matter fiber tracking in patients with space-occupying lesions of the brain: a new technique for neurosurgical planning? by Clark, Chris A, Barrick, Thomas R, Murphy, Mary M, Bell, B.Anthony

“…The technique of fiber tracking based on diffusion tensor imaging offers the unique possibility of localizing the white matter pathways of the brain in vivo…”
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Correlations between in vivo (1)H MRS and ex vivo (1)H HRMAS metabolite measurements in adult human gliomas by Opstad, Kirstie S, Wright, Alan J, Bell, B Anthony, Griffiths, John R, Howe, Franklyn A

“…To assess how accurately ex vivo high-resolution magic angle spinning (HRMAS) proton magnetic resonance spectroscopy ((1)H MRS) from small biopsy tissues…”
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Ex-vivo HRMAS of adult brain tumours: metabolite quantification and assignment of tumour biomarkers by Wright, Alan J, Fellows, Greg A, Griffiths, John R, Wilson, M, Bell, B Anthony, Howe, Franklyn A

“…High-resolution magic angle spinning (HRMAS) NMR spectroscopy allows detailed metabolic analysis of whole biopsy samples for investigating tumour biology and…”
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Development of a decision support system for diagnosis and grading of brain tumours using in vivo magnetic resonance single voxel spectra by Tate, Anne R., Underwood, Joshua, Acosta, Dionisio M., Julià-Sapé, Margarida, Majós, Carles, Moreno-Torres, Àngel, Howe, Franklyn A., van der Graaf, Marinette, Lefournier, Virginie, Murphy, Mary M., Loosemore, Alison, Ladroue, Christophe, Wesseling, Pieter, Luc Bosson, Jean, Cabañas, Miquel E., Simonetti, Arjan W., Gajewicz, Witold, Calvar, Jorge, Capdevila, Antoni, Wilkins, Peter R., Bell, B. Anthony, Rémy, Chantal, Heerschap, Arend, Watson, Des, Griffiths, John R., Arús, Carles

“…A computer‐based decision support system to assist radiologists in diagnosing and grading brain tumours has been developed by the multi‐centre INTERPRET…”
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T cell deficiency does not reduce lesions in mice produced by intracerebral injection of NMO-IgG and complement by Saadoun, Samira, Waters, Patrick, MacDonald, Claire, Bridges, Leslie R, Bell, B. Anthony, Vincent, Angela, Verkman, A.S, Papadopoulos, Marios C

“…Abstract We reported recently that intracerebral administration of NMO-IgG with human complement produces neuromyelitis optica (NMO) lesions in mice. We…”
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