Search Results - "Bell, AW"

Decreased concentration of plasma leptin in periparturient dairy cows is caused by negative energy balance by Block, SS, Butler, WR, Ehrhardt, RA, Bell, AW, Van Amburgh, ME, Boisclair, YR

“…Dairy cows suffer from an intense energy deficit at parturition due to the onset of copious milk synthesis and depressed appetite. Despite this deficit,…”
Get full text

Development of a specific radioimmunoassay to measure physiological changes of circulating leptin in cattle and sheep by Ehrhardt, RA, Slepetis, RM, Siegal-Willott, J, Van Amburgh, ME, Bell, AW, Boisclair, YR

“…Studies of leptin in large domestic ruminants have been limited to measurements of gene expression because methods to measure circulating levels are not…”
Get full text

Characterization of an RNA Granule from Developing Brain by Elvira, George, Wasiak, Sylwia, Blandford, Vanessa, Tong, Xin-Kang, Serrano, Alexandre, Fan, Xiaotang, del Rayo Sánchez-Carbente, Maria, Servant, Florence, Bell, Alexander W., Boismenu, Daniel, Lacaille, Jean-Claude, McPherson, Peter S., DesGroseillers, Luc, Sossin, Wayne S.

“…In brain, mRNAs are transported from the cell body to the processes, allowing for local protein translation at sites distant from the nucleus. Using…”
Get full text

Tandem MS Analysis of Brain Clathrin-Coated Vesicles Reveals Their Critical Involvement in Synaptic Vesicle Recycling by Blondeau, Francois, Ritter, Brigitte, Allaire, Patrick D, Wasiak, Sylwia, Girard, Martine, Hussain, Natasha K, Angers, Annie, Legendre-Guillemin, Valerie, Roy, Line, Boismenu, Daniel, Kearney, Robert E, Bell, Alexander W, Bergeron, John J M, McPherson, Peter S

“…Tandem MS has identified 209 proteins of clathrin-coated vesicles (CCVs) isolated from rat brain. An overwhelming abundance of peptides were assigned to the…”
Get full text

Expression of Notch‐1 and its ligand Jagged‐1 in rat liver during liver regeneration by Köhler, Christoph, Bell, Aaron W., Bowen, William C., Monga, Satdarshan P., Fleig, Wolfgang, Michalopoulos, George K.

“…The Notch/Jagged signaling pathway is important for cellular differentiation and proliferation. Its dysfunction is associated with human pathologies in several…”
Get full text

Digitally encoded DNA nanostructures for multiplexed, single-molecule protein sensing with nanopores by Bell, Nicholas A. W., Keyser, Ulrich F.

“…The simultaneous detection of a large number of different analytes is important in bionanotechnology research and in diagnostic applications. Nanopore sensing…”
Get full text

Enthoprotin: A Novel Clathrin-Associated Protein Identified through Subcellular Proteomics by Wasiak, Sylwia, Legendre-Guillemin, Valerie, Puertollano, Rosa, Blondeau, Francois, Girard, Martine, de Heuvel, Elaine, Boismenu, Daniel, Bell, Alexander W., Bonifacino, Juan S., McPherson, Peter S.

“…Despite numerous advances in the identification of the molecular machinery for clathrin-mediated budding at the plasma membrane, the mechanistic details of…”
Get full text

Acute experimental mastitis is not causal toward the development of energy-related metabolic disorders in early postpartum dairy cows by Waldron, M R, Kulick, A E, Bell, A W, Overton, T R

“…Twenty Holstein cows in early lactation (7 d in milk) were administered 100 microg of Escherichia coli lipopolysaccharide (LPS) dissolved in 10 mL of sterile…”
Get more information

Specific Protein Detection Using Designed DNA Carriers and Nanopores by Bell, Nicholas A. W, Keyser, Ulrich F

“…Nanopores are a versatile technique for the detection and characterization of single molecules in solution. An ongoing challenge in the field is to find…”
Get full text

Consequences of intra-uterine growth retardation for postnatal growth, metabolism and pathophysiology by Greenwood, P L, Bell, A W

“…Intra-uterine growth retardation (IUGR), caused by maternal undernutrition or placental insufficiency, is usually associated with disproportionately large…”
Get more information

Protein nutrition in late pregnancy, maternal protein reserves and lactation performance in dairy cows by Bell, Alan W., Burhans, Winfield S., Overton, Thomas R.

“…Empirical evidence suggests that prolonged underfeeding of protein to late-pregnant dry cows can have modest negative carry-over effects on milk volume and/or…”
Get full text

High-resolution Crystal Structure of Arthrobacter aurescens Chondroitin AC Lyase: An Enzyme–Substrate Complex Defines the Catalytic Mechanism by Lunin, Vladimir V., Li, Yunge, Linhardt, Robert J., Miyazono, Hirofumi, Kyogashima, Mamoru, Kaneko, Takuji, Bell, Alexander W., Cygler, Miroslaw

“…Chondroitin lyases (EC 4.2.2.4 and EC 4.2.2.5) are glycosaminoglycan-degrading enzymes that act as eliminases. Chondroitin lyase AC from Arthrobacter aurescens…”
Get full text

Single Protein Molecule Detection by Glass Nanopores by Li, Wenhong, Bell, Nicholas A. W, Hernández-Ainsa, Silvia, Thacker, Vivek V, Thackray, Alana M, Bujdoso, Raymond, Keyser, Ulrich F

“…Nanopores can be used to detect and analyze single molecules in solution. We have used glass nanopores made by laser-assisted capillary-pulling, as a…”
Get full text

Effects of birth weight and postnatal nutrition on neonatal sheep: II. Skeletal muscle growth and development by Greenwood, P. L, Hunt, A. S, Hermanson, J. W, Bell, A. W

“…This study investigated effects of birth weight and postnatal nutrition on growth and development of skeletal muscles in neonatal lambs. Low (L; mean +/- SD…”
Get full text

TUC-4b, a Novel TUC Family Variant, Regulates Neurite Outgrowth and Associates with Vesicles in the Growth Cone by Quinn, Christopher C, Chen, Esteban, Kinjo, Tashi G, Kelly, Gail, Bell, Alexander W, Elliott, Robert C, McPherson, Peter S, Hockfield, Susan

“…The TUC (TOAD-64/Ulip/CRMP) proteins are homologs of UNC-33, a protein that is required for axon extension and guidance in Caenorhabditis elegans. The TUC…”
Get full text

DNA Origami Nanopores by Bell, Nicholas A. W, Engst, Christian. R, Ablay, Marc, Divitini, Giorgio, Ducati, Caterina, Liedl, Tim, Keyser, Ulrich F

“…We demonstrate the assembly of functional hybrid nanopores for single molecule sensing by inserting DNA origami structures into solid-state nanopores. In our…”
Get full text

Direction- and Salt-Dependent Ionic Current Signatures for DNA Sensing with Asymmetric Nanopores by Chen, Kaikai, Bell, Nicholas A.W., Kong, Jinglin, Tian, Yu, Keyser, Ulrich F.

“…Solid-state nanopores are promising tools for single-molecule detection of both DNA and proteins. In this study, we investigated the patterns of ionic current…”
Get full text

Regulation of placental nutrient transport and implications for fetal growth by Bell, Alan W, Ehrhardt, Richard A

“…Fetal macronutrient requirements for oxidative metabolism and growth are met by placental transport of glucose, amino acids, and, to a lesser extent that…”
Get full text

DNA Origami Nanopores for Controlling DNA Translocation by Hernández-Ainsa, Silvia, Bell, Nicholas A. W, Thacker, Vivek V, Göpfrich, Kerstin, Misiunas, Karolis, Fuentes-Perez, Maria Eugenia, Moreno-Herrero, Fernando, Keyser, Ulrich F

“…We combine DNA origami structures with glass nanocapillaries to reversibly form hybrid DNA origami nanopores. Trapping of the DNA origami onto the…”
Get full text

Spatial and developmental regulation of leptin in fetal sheep by Ehrhardt, Richard A, Bell, Alan W, Boisclair, Yves R

“…To better understand the biology of leptin during prenatal life, the developmental and spatial regulation of leptin was studied in ovine fetuses. Fetal plasma…”
Get more information