B Cell Depletion Therapy as a Cutting-Edge Treatment of Demyelinating Diseases of the Central Nervous System

Demyelinating diseases of the central nervous system and multiple sclerosis in particular are a pressing issue for medical community and society as a whole. Deve- lopment and implementation of highly effective specific therapy significantly slow the disease progression and help maintain patients...

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Bibliographic Details
Published in:	Annaly kliničeskoj i èksperimentalʹnoj nevrologii (Online) Vol. 17; no. 2; pp. 65 - 74
Main Authors:	Simaniv, Taras O., Belkina, Anna A., Zakharova, Maria N.
Format:	Journal Article
Language:	English
Published:	Research Center of Neurology 21-06-2023
Subjects:	b cells central nervous system demyelinating diseases immunomodulatory therapy multiple sclerosis pathogenesis
Online Access:	Get full text
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Summary:	Demyelinating diseases of the central nervous system and multiple sclerosis in particular are a pressing issue for medical community and society as a whole. Deve- lopment and implementation of highly effective specific therapy significantly slow the disease progression and help maintain patients' quality of life and social participation. We analyzed pathogenic mechanisms of multiple sclerosis and other B cell-mediated diseases and reviewed therapeutic options for main disease stages.
ISSN:	2075-5473 2409-2533
DOI:	10.54101/ACEN.2023.2.9