Search Results - "Beliveau, R."

Antitumour activity of ANG1005, a conjugate between paclitaxel and the new brain delivery vector Angiopep‐2 by Régina, A, Demeule, M, Ché, C, Lavallée, I, Poirier, J, Gabathuler, R, Béliveau, R, Castaigne, J‐P

“…Background and purpose: Paclitaxel is highly efficacious in the treatment of breast, head and neck, non‐small cell lung cancers and ovarian carcinoma. For…”
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Influence of glioma tumour microenvironment on the transport of ANG1005 via low-density lipoprotein receptor-related protein 1 by Bertrand, Y, Currie, J-C, Poirier, J, Demeule, M, Abulrob, A, Fatehi, D, Stanimirovic, D, Sartelet, H, Castaigne, J-P, Béliveau, R

“…Background: ANG1005 consists of three molecules of paclitaxel conjugated via ester bonds to the 19-amino-acid peptide Angiopep-2. The new chemical agent has…”
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Matrix metalloproteinase inhibition by green tea catechins by Demeule, Michel, Brossard, Mathieu, Pagé, Martine, Gingras, Denis, Béliveau, Richard

“…We have investigated the effects of different biologically active components from natural products, including green tea polyphenols (GTP), resveratrol,…”
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Localization of membrane-type 1 matrix metalloproteinase in caveolae membrane domains by Annabi, B, Lachambre, M, Bousquet-Gagnon, N, Pagé, M, Gingras, D, Béliveau, R

“…Membrane-type 1 matrix metalloproteinase (MT1-MMP) is a membrane-associated MMP that has been recently reported to have a central role in tumour cell invasion…”
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P-glycoprotein is localized in caveolae in resistant cells and in brain capillaries by Demeule, Michel, Jodoin, Julie, Gingras, Denis, Béliveau, Richard

“…A significant proportion of P-glycoprotein (P-gp) and caveolin was co-localized in caveolae isolated from resistant (CH RC5) cells overexpressing P-gp and from…”
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Effect of graded levels of wheat-based dried distillers’ grains with solubles on rumen fermentation in finishing cattle by Beliveau, R.M, McKinnon, J.J

“…A 4 × 4 Latin square experiment using ruminally cannulated heifers (388 ± 25 kg, mean ± SD) was conducted to evaluate the effects of graded levels (0, 7, 14,…”
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Impaired tyrosine phosphorylation of membrane type 1-matrix metalloproteinase reduces tumor cell proliferation in three-dimensional matrices and abrogates tumor growth in mice by Nyalendo, Carine, Beaulieu, Edith, Sartelet, Hervé, Michaud, Marisol, Fontaine, Nicolas, Gingras, Denis, Béliveau, Richard

“…Pericellular proteolysis of the extracellular matrix by membrane type 1-matrix metalloproteinase (MT1-MMP) confers tumor cells with the ability to proliferate…”
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P-glycoprotein is strongly expressed in the luminal membranes of the endothelium of blood vessels in the brain by Beaulieu, E, Demeule, M, Ghitescu, L, Béliveau, R

“…Luminal membranes of the vascular endothelium were isolated from brain, heart and lungs by modification of their density. The presence of P-glycoprotein (P-gp)…”
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Hyaluronan Cell Surface Binding Is Induced by Type I Collagen and Regulated by Caveolae in Glioma Cells by Annabi, Borhane, Thibeault, Sébastien, Moumdjian, Robert, Béliveau, Richard

“…Hyaluronan (HA) is a component of the brain extracellular matrix environment that is synthesized and secreted by glioma cells. The primary cell surface…”
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Isolation of Endothelial Cells from Brain, Lung, and Kidney: Expression of the Multidrug Resistance P-Glycoprotein Isoforms by Demeule, Michel, Labelle, Myriam, Régina, Anthony, Berthelet, France, Béliveau, Richard

“…Endothelial cells (EC) were isolated from brain, lung, and renal cortex using magnetic microbeads cross-linked to an antibody directed against the…”
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Regulation of brain endothelial cells migration and angiogenesis by P-glycoprotein/caveolin-1 interaction by Barakat, Stéphane, Turcotte, Sandra, Demeule, Michel, Lachambre, Marie-Paule, Régina, Anthony, Baggetto, Loris G., Béliveau, Richard

“…We have investigated the involvement of P-glycoprotein (P-gp)/caveolin-1 interaction in the regulation of brain endothelial cells (EC) migration and…”
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Activation of the extracellular signal-regulated protein kinase (ERK) cascade by membrane-type-1 matrix metalloproteinase (MT1-MMP) by Gingras, Denis, Bousquet-Gagnon, Nathalie, Langlois, Stéphanie, Lachambre, Marie-Paule, Annabi, Borhane, Béliveau, Richard

“…The mechanisms underlying membrane-type-1 matrix metalloproteinase (MT1-MMP)-dependent induction of cell migration were investigated. Overexpression of MT1-MMP…”
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Tyrosine phosphorylation of the vascular endothelial-growth-factor receptor-2 (VEGFR-2) is modulated by Rho proteins by Gingras, D, Lamy, S, Béliveau, R

“…The effects of Rho-specific modifying toxins on the tyrosine phosphorylation of endothelial cell proteins were investigated. Incubation of the cells with the…”
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Matrix proteinase inhibition by AE-941, a multifunctional antiangiogenic compound by Gingras, D, Renaud, A, Mousseau, N, Beaulieu, E, Kachra, Z, Béliveau, R

“…Matrix metalloproteinases (MMPs) play an important role in tissue remodeling under normal physiological and pathological conditions and are thus attractive…”
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Multidrug resistance in brain tumors: roles of the blood-brain barrier by Régina, A, Demeule, M, Laplante, A, Jodoin, J, Dagenais, C, Berthelet, F, Moghrabi, A, Béliveau, R

“…Malignant brain tumors and brain metastases present a formidable clinical challenge against which no significant advances have been made over the last decade…”
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Cisplatin induces renal expression of P-glycoprotein and canalicular multispecific organic anion transporter by Demeule, M, Brossard, M, Béliveau, R

“…The expression of two members of the ATP-binding cassette family of transport proteins, P-glycoprotein (P-gp) and the canalicular multispecific organic anion…”
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Dexamethasone modulation of multidrug transporters in normal tissues by Demeule, Michel, Jodoin, Julie, Beaulieu, Édith, Brossard, Mathieu, Béliveau, Richard

“…The expression of P-glycoprotein (P-gp) and canalicular multispecific organic anion transporter (cMOAT or Mrp2) was evaluated by Western blotting analysis of…”
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Cyclosporin A treatment induces overexpression of P-glycoprotein in the kidney and other tissues by Jetté, L, Beaulieu, E, Leclerc, J M, Béliveau, R

“…To see whether P-glycoprotein (PGP) expressed in renal brush-border membranes (BBM) could interact with compounds known as modulators of multidrug resistance…”
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Expression of matrix metalloproteinases and their inhibitors in human brain tumors by Kachra, Z, Beaulieu, E, Delbecchi, L, Mousseau, N, Berthelet, F, Moumdjian, R, Del Maestro, R, Béliveau, R

“…Sixty human brain tumors, classified according to the New World Health Organization (WHO) classification including, grade I schwannomas, meningiomas and…”
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Expression of multidrug‐resistance P‐glycoprotein (MDR1) in human brain tumors by Demeule, Michel, Shedid, Daniel, Beaulieu, Édith, Del Maestro, Rolando F., Moghrabi, Albert, Ghosn, Pierre B., Moumdjian, Robert, Berthelet, France, Béliveau, Richard

“…Multidrug resistance (MDR) is associated with the expression of P‐glycoprotein (P‐gp), an ATP‐dependent transporter which expels anti‐cancer drugs from cells…”
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