Search Results - "Beliveau, J"
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Spatial organization of chromatin domains and compartments in single chromosomes
Published in Science (American Association for the Advancement of Science) (05-08-2016)“…The spatial organization of chromatin critically affects genome function. Recent chromosome-conformation-capture studies have revealed topologically…”
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2
SABER amplifies FISH: enhanced multiplexed imaging of RNA and DNA in cells and tissues
Published in Nature methods (01-06-2019)“…Fluorescence in situ hybridization (FISH) reveals the abundance and positioning of nucleic acid sequences in fixed samples. Despite recent advances in…”
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OligoMiner provides a rapid, flexible environment for the design of genome-scale oligonucleotide in situ hybridization probes
Published in Proceedings of the National Academy of Sciences - PNAS (06-03-2018)“…Oligonucleotide (oligo)-based FISH has emerged as an important tool for the study of chromosome organization and gene expression and has been empowered by the…”
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4
Metaelliptical copulas and their use in frequency analysis of multivariate hydrological data
Published in Water resources research (01-09-2007)“…Metaelliptical copulas are introduced as a flexible tool for modeling multivariate data in hydrology. The properties of this broad class of dependence…”
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5
Multiplexed 3D super-resolution imaging of whole cells using spinning disk confocal microscopy and DNA-PAINT
Published in Nature communications (12-12-2017)“…Single-molecule localization microscopy (SMLM) can visualize biological targets on the nanoscale, but complex hardware is required to perform SMLM in thick…”
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6
Islands of retroelements are major components of Drosophila centromeres
Published in PLoS biology (14-05-2019)“…Centromeres are essential chromosomal regions that mediate kinetochore assembly and spindle attachments during cell division. Despite their functional…”
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7
3D mapping and accelerated super-resolution imaging of the human genome using in situ sequencing
Published in Nature methods (01-08-2020)“…There is a need for methods that can image chromosomes with genome-wide coverage, as well as greater genomic and optical resolution. We introduce OligoFISSEQ,…”
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The chiropractic profession: a scoping review of utilization rates, reasons for seeking care, patient profiles, and care provided
Published in Chiropractic & manual therapies (22-11-2017)“…Previous research has investigated utilization rates, who sees chiropractors, for what reasons, and the type of care that chiropractors provide. However, these…”
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9
Single-molecule super-resolution imaging of chromosomes and in situ haplotype visualization using Oligopaint FISH probes
Published in Nature communications (12-05-2015)“…Fluorescence in situ hybridization (FISH) is a powerful single-cell technique for studying nuclear structure and organization. Here we report two advances in…”
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10
Versatile design and synthesis platform for visualizing genomes with Oligopaint FISH probes
Published in Proceedings of the National Academy of Sciences - PNAS (26-12-2012)“…A host of observations demonstrating the relationship between nuclear architecture and processes such as gene expression have led to a number of new…”
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11
Scalable amplification of strand subsets from chip-synthesized oligonucleotide libraries
Published in Nature communications (16-11-2015)“…Synthetic oligonucleotides are the main cost factor for studies in DNA nanotechnology, genetics and synthetic biology, which all require thousands of these at…”
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12
Tigerfish designs oligonucleotide-based in situ hybridization probes targeting intervals of highly repetitive DNA at the scale of genomes
Published in Nature communications (03-02-2024)“…Fluorescent in situ hybridization (FISH) is a powerful method for the targeted visualization of nucleic acids in their native contexts. Recent technological…”
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13
An open source 16-channel fluidics system for automating sequential fluorescent in situ hybridization (FISH)-based imaging
Published in HardwareX (01-10-2022)“…[Display omitted] Fluorescent in situ hybridization (FISH) can provide spatial information about DNA/RNA targets in fixed cells and tissues. However, the…”
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14
Cohesin controls X chromosome structure remodeling and X-reactivation during mouse iPSC-reprogramming
Published in Proceedings of the National Academy of Sciences - PNAS (24-01-2023)“…Reactivation of the inactive X chromosome is a hallmark epigenetic event during reprogramming of mouse female somatic cells to induced pluripotent stem cells…”
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15
Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2 islands in euchromatin
Published in PLoS genetics (23-03-2020)“…Membraneless pericentromeric heterochromatin (PCH) domains play vital roles in chromosome dynamics and genome stability. However, our current understanding of…”
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16
Germline progenitors escape the widespread phenomenon of homolog pairing during Drosophila development
Published in PLoS genetics (01-12-2013)“…Homolog pairing, which plays a critical role in meiosis, poses a potential risk if it occurs in inappropriate tissues or between nonallelic sites, as it can…”
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Understanding patient profiles and characteristics of current chiropractic practice: a cross-sectional Ontario Chiropractic Observation and Analysis STudy (O-COAST)
Published in BMJ open (01-08-2019)“…ObjectivesThere is no current detailed profile of people seeking chiropractic care in Canada. We describe the profiles of chiropractors’ practice and the…”
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Correction to: Are personnel with a past history of mental disorders disproportionately vulnerable to the effects of deployment-related trauma? A cross-sectional study of Canadian military personnel
Published in BMC psychiatry (01-07-2019)“…Following publication of the original article [1], we have been notified that the copyright holder needs to be changed from ©The Author(s) to ©Crown…”
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Research priorities of the Canadian chiropractic profession: a consensus study using a modified Delphi technique
Published in Chiropractic & manual therapies (12-12-2017)“…Research funds are limited and a healthcare profession that supports research activity should establish research priority areas. The study objective was to…”
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Are personnel with a past history of mental disorders disproportionately vulnerable to the effects of deployment-related trauma? A cross-sectional study of Canadian military personnel
Published in BMC psychiatry (22-05-2019)“…Past mental disorders predict future disorders, both in the presence and absence of trauma exposure. However, it is not clear whether those with past mental…”
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