Search Results - "Belinsky, M G"
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MOAT-E (ARA) is a full-length MRP/cMOAT subfamily transporter expressed in kidney and liver
Published in British Journal of Cancer (01-07-1999)“…Multidrug resistance-associated protein (MRP) and the canalicular multispecific organic anion transporter (cMOAT) are organic anion pumps that have been linked…”
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Characterization of MOAT-C and MOAT-D, new members of the MRP/cMOAT subfamily of transporter proteins
Published in JNCI : Journal of the National Cancer Institute (18-11-1998)“…Multidrug resistance-associated protein (MRP) and canalicular multispecific organic anion transporter (cMOAT) are transporter proteins that pump organic anions…”
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Isolation of MOAT-B, a widely expressed multidrug resistance-associated protein/canalicular multispecific organic anion transporter-related transporter
Published in Cancer research (Chicago, Ill.) (01-07-1998)“…Multidrug resistance-associated protein (MRP) and canalicular multispecific organic anion transporter (cMOAT) are closely related mammalian ATP-binding…”
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The MRP family of drug efflux pumps
Published in Oncogene (20-10-2003)“…The MRP family is comprised of nine related ABC transporters that are able to transport structurally diverse lipophilic anions and function as drug efflux…”
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Amplification of the ATP-binding cassette 2 transporter gene is functionally linked with enhanced efflux of estramustine in ovarian carcinoma cells
Published in Cancer research (Chicago, Ill.) (01-04-1998)“…An estramustine-resistant human ovarian carcinoma cell line, SKEM, was generated to explore resistance mechanisms associated with this agent. Cytogenetic…”
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MRP8, ATP-binding Cassette C11 (ABCC11), Is a Cyclic Nucleotide Efflux Pump and a Resistance Factor for Fluoropyrimidines 2′,3′-Dideoxycytidine and 9′-(2′-Phosphonylmethoxyethyl)adenine
Published in The Journal of biological chemistry (08-08-2003)“…MRP8 (ABCC11) is a recently identified cDNA that has been assigned to the multidrug resistance-associated protein (MRP) family of ATP-binding cassette…”
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Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: Effect of polyglutamylation on MTX transport
Published in Cancer research (Chicago, Ill.) (01-10-2001)“…We have recently determined that human multidrug resistance protein (MRP) 3, which confers resistance to certain natural product agents and methotrexate (MTX),…”
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Analysis of the structure and expression pattern of MRP7 (ABCC10), a new member of the MRP subfamily
Published in Cancer letters (26-01-2001)“…The MRP subfamily of ABC transporters currently consists of at least six members, several of which have been demonstrated to transport amphipathic anions and…”
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Expression of multidrug resistance protein-3 (multispecific organic anion transporter-D) in human embryonic kidney 293 cells confers resistance to anticancer agents
Published in Cancer research (Chicago, Ill.) (01-12-1999)“…Multidrug resistance-associated protein (MRP)1 and canalicular multispecific organic anion transporter (cMOAT)/MRP2 are ATP-binding cassette (ABC) transporters…”
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MRP subfamily transporters and resistance to anticancer agents
Published in Journal of bioenergetics and biomembranes (01-12-2001)“…The MRP subfamily of ABC transporters from mammals consists of at least seven members, six of which have been implicated in the transport of amphipathic…”
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Cloning and characterization of human adenosine 5'-triphosphate-binding cassette, sub-family A, transporter 2 (ABCA2)
Published in Cancer research (Chicago, Ill.) (15-04-2001)“…We have isolated the full-length cDNA for human ATP-binding cassette, sub-family A, member 2 transporter (ABCA2). The ORF of this cDNA encodes a protein…”
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Reversal of drug resistance mediated by multidrug resistance protein (MRP) 1 by dual effects of agosterol a on MRP1 function
Published in International journal of cancer (01-07-2001)“…We previously isolated agosterol A (AG‐A) from a marine Spongia sp. and found that it completely reversed colchicine resistance in P‐glycoprotein…”
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Internally deleted antigenomic hepatitis delta RNA self-cleaves even in 18 M formamide
Published in Annals of the New York Academy of Sciences (01-10-1992)Get more information
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Structure and in Vitro Substrate Specificity of the Murine Multidrug Resistance-Associated Protein
Published in Biochemistry (Easton) (22-10-1996)“…MRP is a recently described ATP-binding cassette transporter that confers cellular resistance to natural product cytotoxic drugs. To examine the biochemical…”
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Modification interference analysis of a self-cleaving RNA from hepatitis delta virus
Published in The FASEB journal (01-01-1993)“…A chemical modification-interference assay was used to evaluate the sequence requirements for self-cleavage of a 73-nucleotide self-cleaving RNA from the…”
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Non-ribozyme sequences enhance self-cleavage of ribozymes derived from Hepatitis delta virus
Published in Nucleic acids research (11-02-1991)“…Analysis of the self-cleavage of ribozymes derived from the genomic RNA of Hepatitis delta virus (HDV) has revealed that certain co-transcribed vector…”
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Correlation of gastrointestinal stromal tumor (GIST) gene expression signatures and response to imatinib mesylate in the Radiation Therapy Oncology Group phase II clinical trial S-0132
Published in Journal of clinical oncology (20-05-2009)“…Abstract only 10533 Background: Despite the known efficacy of imatinib mesylate (IM) in metastatic GIST, both primary and secondary drug resistance remain a…”
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Analysis of the drug resistance profile of multidrug resistance protein 7 (ABCC10): Resistance to docetaxel
Published in Cancer research (Chicago, Ill.) (15-07-2004)“…The multidrug resistance protein (MRP) family consists of nine members that can be categorized according to whether or not a third (NH(2)-terminal)…”
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Characterization of the drug resistance and transport properties of multidrug resistance protein 6 (MRP6, ABCC6)
Published in Cancer research (Chicago, Ill.) (01-11-2002)“…Mutations in human multidrug resistance protein 6 (MRP6, ABCC6), a member of the MRP family of drug efflux pumps, are the genetic basis of Pseudoxanthoma…”
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