Search Results - "Belini Júnior, Édis"

Inflammation in Sickle Cell Disease: Differential and Down-Expressed Plasma Levels of Annexin A1 Protein by Torres, Lidiane S, Okumura, Jéssika V, Silva, Danilo G H, Mimura, Kallyne K O, Belini-Júnior, Édis, Oliveira, Renan G, Lobo, Clarisse L C, Oliani, Sonia M, Bonini-Domingos, Claudia R

“…Sickle cell disease (SCD) is an inherited hemolytic anemia whose pathophysiology is driven by polymerization of the hemoglobin S (Hb S), leading to hemolysis…”
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Correction: Inflammation in Sickle Cell Disease: Differential and Down-Expressed Plasma Levels of Annexin A1 Protein by Torres, Lidiane S, Okumura, Jéssika V, Silva, Danilo G H, Mimura, Kallyne K O, Belini-Júnior, Édis, Oliveira, Renan G, Lobo, Clarisse L C, Oliani, Sonia M, Bonini-Domingos, Claudia R

“…[This corrects the article DOI: 10.1371/journal.pone.0165833.]…”
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Plasma levels of TGF-β1 in homeostasis of the inflammation in sickle cell disease by Torres, Lidiane de Souza, Okumura, Jéssika Viviani, Silva, Danilo Grünig Humberto da, Belini Júnior, Édis, Oliveira, Renan Garcia de, Mimura, Kallyne Kioko Oliveira, Lobo, Clarisse Lopes de Castro, Oliani, Sonia Maria, Bonini Domingos, Claudia Regina

“…•We evaluated plasma levels of TGF-β1 in sickle cell disease.•TGF-β1 levels were high in patients with sickle cell disease.•TGF-β1 was positively correlated to…”
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Phenotypic Diversity of Sickle Cell Disease in Patients with a Double Heterozygosity for Hb S and Hb D-Punjab by Torres, Lidiane S., Okumura, Jéssika V., Belini-Júnior, Édis, Oliveira, Renan G., Nascimento, Patrícia P., Silva, Danilo G.H., Lobo, Clarisse L.C., Oliani, Sonia M., Bonini-Domingos, Claudia R.

“…Phenotypic heterogeneity for sickle cell disease is associated to several genetic factors such as genotype for sickle cell disease, β-globin gene cluster…”
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The relationship between of ACE I/D and the MTHFR C677T polymorphisms in the pathophysiology of type 2 diabetes mellitus in a population of Brazilian obese patients by Pirozzi, Flavio Fontes, Belini Junior, Edis, Okumura, Jessika Viviani, Salvarani, Mariana, Bonini-Domingos, Claudia Regina, Ruiz, Milton Artur

“…Objectives This study aimed to evaluate the frequencies of the angiotensin converting enzyme (ACE) gene insertion/deletion (I/D) and methylenetetrahydrofolate…”
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Atypical β-S haplotypes: classification and genetic modulation in patients with sickle cell anemia by Okumura, Jéssika V, Silva, Danilo G H, Torres, Lidiane S, Belini-Junior, Edis, Venancio, Larissa P R, Carrocini, Gisele C S, Nascimento, Patrícia P, Lobo, Clarisse L C, Bonini-Domingos, Claudia R

“…β-S globin haplotype (β haplotype) characterization in sickle cell anemia (SCA) patients is important because it assists individualized treatment. However, the…”
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The XmnI polymorphic site 5' to the gene G(γ) in a Brazilian patient with sickle cell anaemia - fetal haemoglobin concentration, haematology and clinical features by Belini Júnior, Edis, Cançado, Rodolfo D, Domingos, Claudia R B

“…We report a 20-year-old female with sickle cell anaemia and with an HbF concentration of 15.8%. The patient was not using hydroxyurea and was not receiving…”
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The XmnI polymorphic site 5’ to the gene Gγ in a Brazilian patient with sickle cell anaemia – fetal haemoglobin concentration, haematology and clinical features by Belini Júnior, Édis, D. Cançado, Rodolfo, Domingos, Claudia R.B.

“…We report a 20-year-old female with sickle cell anaemia and with an HbF concentration of 15.8%. The patient was not using hydroxyurea and was not receiving…”
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Incidence of hemoglobinopathies and spatialization of newborns with sickle cell trait in Mato Grosso do Sul, Brazil by Cândido-Bacani, Priscila de Matos, Grilo, Patrícia Medeiros Silva, Ramos, Vanessa da Silveira, Zanchin, Michelly, Pereira, Indiara Correia, Oliveira, Josaine Sousa Palmieri, Bacani, Vitor Matheus, Belini Junior, Edis

“…To evaluate the incidence of variant hemoglobins of newborn samples from the Neonatal Screening Center in the state of Mato Grosso do Sul, Brazil, and to…”
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Association of HMIP1 C-893A polymorphism and disease severity in patients with sickle cell anemia by Pereira-Martins, Diego A, Domingos, Igor F, Belini-Junior, Edis, Coelho-Silva, Juan L, Weinhäuser, Isabel, Araújo, Aderson S, Lobo, Clarisse L, Bonini-Domingos, Claudia R, Bezerra, Marcos A, Lucena-Araujo, Antonio R

“…INTRODUCTIONSickle cell anemia (SCA) is a Mendelian disorder with a heterogeneous clinical course. The reasons for this phenotypic diversity are not entirely…”
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Inheritance of the Bantu/Benin haplotype causes less severe hemolytic and oxidative stress in sickle cell anemia patients treated with hydroxycarbamide by Okumura, Jéssika V, Silva, Danilo G H, Torres, Lidiane S, Belini-Junior, Edis, Barberino, Willian M, Oliveira, Renan G, Carrocini, Gisele C S, Gelaleti, Gabriela B, Lobo, Clarisse L C, Bonini-Domingos, Claudia R

“…Beta S-globin gene cluster haplotypes (β(S)-haplotypes) can modulate the response to hydroxycarbamide (HC) treatment in sickle cell anemia (SCA) patients. In…”
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Is nullity for Glutathione S-transferase genes GSTT1 and GSTM1 protective against leprosy? by Graça, Carla Renata, Cordeiro-Soubhia, Rosa Maria, Tonelli-Nardi, Susilene Maria, Junior, Edis Belini, Bonini-Domingos, Claudia Regina, Gauch, Camila Ravazzi, Rocha, Elisabeth Martins Da Silva Da, Paschoal, Vânia Deĺarco, Kouyoumdjian, João Aris, Baptista, Andrea Regina De Souza

“…Introduction: Leprosy is a slow and progressive infectious disease caused by Mycobacterium leprae. The generation of free radicals called reactive oxygen…”
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Incidence of hemoglobinopathies and diagnostic algorithm in newborns in the state of Mato Grosso do Sul by Parente, Giovanna da Silva, David, Thaís Cavichio, Zanchin, Michelly, Palmier, Josiane de Sousa, Belini Júnior, Edis

“…Introduction: Hemoglobinopathies are inherited disorders that affect the normal aspect of human hemoglobin (Hb). The disorders can be structural defect in one…”
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The influence of hydroxyurea on oxidative stress in sickle cell anemia by Torres, Lidiane de Souza, da Silva, Danilo Grünig Humberto, Belini Junior, Edis, de Almeida, Eduardo Alves, Lobo, Clarisse Lopes de Castro, Cançado, Rodolfo Delfini, Ruiz, Milton Artur, Bonini-Domingos, Claudia Regina

“…The oxidative stress in 20 sickle cell anemia patients taking hydroxyurea and 13 sickle cell anemia patients who did not take hydroxyurea was compared with a…”
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Oxidative stress in sickle cell disease: An overview of erythrocyte redox metabolism and current antioxidant therapeutic strategies by Silva, Danilo Grunig Humberto, Belini Junior, Edis, de Almeida, Eduardo Alves, Bonini-Domingos, Claudia Regina

“…Erythrocytes have an environment of continuous pro-oxidant generation due to the presence of hemoglobin (Hb), which represents an additional and quantitatively…”
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Yeast enhancement by mass mating and selective pressure for the integrated production process of first and second-generation ethanol by Muynarsk, Elisangela de Souza Miranda, Christofoleti-Furlan, Renata Maria, Colonia, Brigitte Sthepani Orozco, Belini Junior, Edis, Silva, Danilo Grünig Humberto da, Basso, Luiz Carlos

“…Second-generation ethanol production is a worldwide applicable technology with the potential to replace fossil fuels and contribute to sustainability. The…”
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Impact of genetic polymorphisms in key enzymes of homocysteine metabolism on the pathophysiology of sickle cell anemia by da Silva, Danilo Grünig Humberto, Belini Junior, Edis, de Souza Torres, Lidiane, Okumura, Jessika Viviani, Marcel Barberino, Willian, Garcia de Oliveira, Renan, Urbinatti Teixeira, Vanessa, Lopes de Castro Lobo, Clarisse, Alves de Almeida, Eduardo, Bonini-Domingos, Claudia Regina

“…This work aimed at studying a possible influence of methylenetetrahydrofolate reductase (MTHFR; c. 677C>T) and cystathionine β-synthase (CBS; 844ins68)…”
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Severity of Brazilian sickle cell disease patients: Severity scores and feasibility of the Bayesian network model use by Belini Junior, Edis, Silva, Danilo Grünig Humberto, Torres, Lidiane de Souza, Okumura, Jéssika Viviani, Lobo, Clarisse Lopes de Castro, Bonini-Domingos, Claudia Regina

“…The integration of the several clinical and laboratory dimensions and the influence of each parameter on the sickle cell disease (SCD)-related mortality is…”
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Comet Assay as a technique to evaluate DNA damage in sickle cell anemia patients by Barberino, Willian Marcel, Belini-Junior, Edis, Bonini-Domingos, Claudia Regina

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Relationship between oxidative stress, glutathione S-transferase polymorphisms and hydroxyurea treatment in sickle cell anemia by Silva, Danilo Grünig Humberto, Belini Junior, Edis, Torres, Lidiane de Souza, Ricci Júnior, Octávio, Lobo, Clarisse de Castro, Bonini-Domingos, Claudia Regina, de Almeida, Eduardo Alves

“…This study evaluated the oxidative stress and antioxidant capacity markers in sickle cell anemia (SCA) patients with and without treatment with hydroxyurea. We…”
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