Search Results - "Belin, David"
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Myelin: A gatekeeper of activity-dependent circuit plasticity?
Published in Science (American Association for the Advancement of Science) (12-11-2021)“…The brain is responsive to an ever-changing environment, enabling the organism to learn and change behavior accordingly. Efforts to understand the…”
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Opiate versus psychostimulant addiction: the differences do matter
Published in Nature reviews. Neuroscience (01-11-2011)“…Current theories of addiction all argue for a unitary account of drug addiction. Badiani and colleagues challenge this view by highlighting behavioural,…”
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Neural mechanisms underlying the vulnerability to develop compulsive drug-seeking habits and addiction
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (12-10-2008)“…We hypothesize that drug addiction can be viewed as the endpoint of a series of transitions from initial voluntary drug use through the loss of control over…”
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High Impulsivity Predicts the Switch to Compulsive Cocaine-Taking
Published in Science (American Association for the Advancement of Science) (06-06-2008)“…Both impulsivity and novelty-seeking have been suggested to be behavioral markers of the propensity to take addictive drugs. However, their relevance for the…”
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Double Dissociation of the Dorsomedial and Dorsolateral Striatal Control Over the Acquisition and Performance of Cocaine Seeking
Published in Neuropsychopharmacology (New York, N.Y.) (01-10-2012)“…The present study investigated the involvement of dopamine-dependent mechanisms in the anterior dorsolateral (aDLS) and posterior dorsomedial (pDMS) striatum…”
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High-Novelty-Preference Rats are Predisposed to Compulsive Cocaine Self-administration
Published in Neuropsychopharmacology (New York, N.Y.) (01-02-2011)“…Sensation/novelty-seeking is amongst the best markers of cocaine addiction in humans. However, its implication in the vulnerability to cocaine addiction is…”
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Writing a constructive peer review: a young PI perspective
Published in The European journal of neuroscience (01-12-2016)Get full text
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Parallel and interactive learning processes within the basal ganglia: Relevance for the understanding of addiction
Published in Behavioural brain research (12-04-2009)“…In this review we discuss the evidence that drug addiction, defined as a maladaptive compulsive habit, results from the progressive subversion by addictive…”
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Evidence for Addiction-like Behavior in the Rat
Published in Science (American Association for the Advancement of Science) (13-08-2004)“…Although the voluntary intake of drugs of abuse is a behavior largely preserved throughout phylogeny, it is currently unclear whether pathological drug use…”
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Basolateral and central amygdala differentially recruit and maintain dorsolateral striatum-dependent cocaine-seeking habits
Published in Nature communications (14-12-2015)“…In the development of addiction, drug seeking becomes habitual and controlled by drug-associated cues, and the neural locus of control over behaviour shifts…”
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Withdrawal from escalated cocaine self-administration impairs reversal learning by disrupting the effects of negative feedback on reward exploitation: a behavioral and computational analysis
Published in Neuropsychopharmacology (New York, N.Y.) (01-12-2019)“…Addiction is regarded as a disorder of inflexible choice with behavior dominated by immediate positive rewards over longer-term negative outcomes. However, the…”
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Pramipexole restores behavioral inhibition in highly impulsive rats through a paradoxical modulation of frontostriatal networks
Published in Translational psychiatry (09-02-2024)“…Impulse control disorders (ICDs), a wide spectrum of maladaptive behaviors which includes pathological gambling, hypersexuality and compulsive buying, have…”
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Increased Impulsivity Retards the Transition to Dorsolateral Striatal Dopamine Control of Cocaine Seeking
Published in Biological psychiatry (1969) (01-07-2014)“…Background Development of maladaptive drug-seeking habits occurs in conjunction with a ventral-to-dorsal striatal shift in dopaminergic control over behavior…”
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Atomoxetine Decreases Vulnerability to Develop Compulsivity in High Impulsive Rats
Published in Biological psychiatry (1969) (15-05-2014)“…Background The factors contributing to the development and severity of obsessive-compulsive spectrum disorders such as obsessive-compulsive disorder,…”
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Exogenous neuropeptide Y promotes in vivo hippocampal neurogenesis
Published in Hippocampus (01-03-2011)“…Adult neurogenesis mainly occurs in two brain regions, the subventricular zone and the dentate gyrus (DG) of the hippocampus. Neuropeptide Y (NPY) is widely…”
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Dissociable Control of Impulsivity in Rats by Dopamine D2 3 Receptors in the Core and Shell Subregions of the Nucleus Accumbens
Published in Neuropsychopharmacology (New York, N.Y.) (01-01-2010)“…Previous research has identified the nucleus accumbens (NAcb) as an important brain region underlying inter-individual variation in impulsive behavior. Such…”
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SEX-SPECIFIC IMPACT OF CHRONIC STRESS ON DECISION-MAKING ASSESSED IN OPERANT MOUSE GAMBLING PARADIGM
Published in IBRO neuroscience reports (01-10-2023)Get full text
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Nigrostriatal Dopaminergic Denervation Does Not Promote Impulsive Choice in the Rat: Implication for Impulse Control Disorders in Parkinson's Disease
Published in Frontiers in behavioral neuroscience (13-12-2018)“…Impulse control disorders (ICDs) are frequent behavioral complications of dopaminergic (DA) replacement therapies (DRTs) in Parkinson's disease (PD). Impulsive…”
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Safety and efficacy of repetitive transcranial magnetic stimulation in the treatment of obsessive-compulsive disorder: A review
Published in The world journal of biological psychiatry (01-03-2012)“…Abstract Objectives. Obsessive-compulsive disorder (OCD) is a chronic, often severe, neuropsychiatric disorder leading to a dramatic impairment in…”
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The Basolateral Amygdala and Nucleus Accumbens Core Mediate Dissociable Aspects of Drug Memory Reconsolidation
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-09-2010)“…A distributed limbic-corticostriatal circuitry is implicated in cue-induced drug craving and relapse. Exposure to drug-paired cues not only precipitates…”
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