Search Results - "Beliakoff, Jason"
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1
The Novel PIAS-like Protein hZimp10 Enhances Smad Transcriptional Activity
Published in The Journal of biological chemistry (18-08-2006)“…Transforming growth factor β (TGF-β) plays critical roles in the control of cell proliferation, differentiation, and apoptosis. Smad proteins are substrates of…”
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Journal Article -
2
Intron-Mediated Enhancement of Gene Expression Independent of Unique Intron Sequences and Splicing
Published in Plant physiology (Bethesda) (01-02-2000)“…Either of the first two introns of the Arabidopsis tryptophan pathway gene PAT1 elevates mRNA accumulation from a PAT1:β-glucuronidase (GUS) fusion roughly…”
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Journal Article -
3
Hormone-Refractory Breast Cancer Remains Sensitive to the Antitumor Activity of Heat Shock Protein 90 Inhibitors
Published in Clinical cancer research (15-10-2003)“…Purpose: The antiestrogen tamoxifen (Tam) has been used as therapy against estrogen receptor (ER)-positive breast cancer for decades. Most tumors respond…”
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Journal Article -
4
The PIAS-Like Protein Zimp10 Is Essential for Embryonic Viability and Proper Vascular Development
Published in Molecular and Cellular Biology (01-01-2008)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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5
An Estrogen Receptor-α/p300 Complex Activates the BRCA-1 Promoter at an AP-1 Site That Binds Jun/Fos Transcription Factors: Repressive Effects of p53 on BRCA-1 Transcription
Published in Neoplasia (New York, N.Y.) (01-09-2005)“…One of the puzzles in cancer predisposition is that women carrying BRCA-1 mutations preferentially develop tumors in epithelial tissues of the breast, ovary…”
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Journal Article -
6
Zimp7 and Zimp10, two novel PIAS-like proteins, function as androgen receptor coregulators
Published in Nuclear receptor signaling (2006)“…The androgen receptor (AR) plays a critical role in male sexual development and in normal and malignant prostate cell growth and survival. It has been shown…”
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Journal Article -
7
novel PIAS-like protein hZimp10 is a transcriptional co-activator of the p53 tumor suppressor
Published in Nucleic acids research (01-07-2007)“…The tumor suppressor, p53, plays critical roles in the cell cycle progression, DNA repair and apoptosis. The PIAS proteins (protein inhibitor of activated…”
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Journal Article -
8
Hsp90: an emerging target for breast cancer therapy
Published in Anti-cancer drugs (01-08-2004)“…Rapidly evolving insights into the specific molecular genetic abnormalities that drive the growth and metastasis of breast cancer have led to the development…”
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Journal Article -
9
Hsp90: an emerging target for breast cancer therapy
Published in Anti-cancer drugs (01-08-2004)Get full text
Journal Article -
10
promoting role of androgen receptor in androgen-sensitive and -insensitive prostate cancer cells
Published in Nucleic acids research (01-04-2007)“…Although the vital role of the androgen receptor (AR) has been well demonstrated in primary prostate cancers, its role in the androgen-insensitive prostate…”
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Journal Article -
11
Hsp90 inhibitors deplete key anti‐apoptotic proteins in pediatric solid tumor cells and demonstrate synergistic anticancer activity with cisplatin
Published in International journal of cancer (10-01-2005)“…Drugs that inhibit the function of heat shock protein 90 (Hsp90) are of interest in the treatment of pediatric cancers because these agents deplete the…”
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Journal Article -
12
hZimp7, a Novel PIAS-Like Protein, Enhances Androgen Receptor-Mediated Transcription and Interacts with SWI/SNF-Like BAF Complexes
Published in Molecular endocrinology (Baltimore, Md.) (01-12-2005)“…Members of the PIAS (protein inhibitor of activated signal transducer and activator of transcription) family are negative regulators of the Janus family of…”
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Journal Article -
13
Intorn-mediated enhancement of gene expression independent of unique intron sequences and splicing
Published in Plant physiology (Bethesda) (01-02-2000)“…Either of the first two introns of the Arabidopsis tryptophan pathway gene PAT1 elevates mRNA accumulation from a PAT1:beta-glucuronidase (GUS) fusion roughly…”
Get full text
Journal Article -
14
Intron-Mediated Enhancement of Gene Expression Independent of Unique Intron Sequences and Splicing1
Published in Plant physiology (Bethesda) (01-02-2000)“…Either of the first two introns of the Arabidopsis tryptophan pathway gene PAT1 elevates mRNA accumulation from a PAT1 :β-glucuronidase (GUS) fusion roughly…”
Get full text
Journal Article -
15
An Estrogen Receptor-α/p300 Complex Activates the BRCA-1 Promoter at an AP-1 Site That Binds Jun/Fos Transcription Factors: Repressive Effects of p53 on BRCA-1 Transcription1
Published in Neoplasia (New York, N.Y.) (01-09-2005)“…One of the puzzles in cancer predisposition is that women carrying BRCA-1 mutations preferentially develop tumors in epithelial tissues of the breast and…”
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Journal Article -
16
Regulation of estrogen receptor function by molecular chaperones
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Dissertation -
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Regulation of estrogen receptor function by molecular chaperones
Published 01-01-2003“…The estrogen receptor (ER) plays a major role in breast cancer progression, and ER+ tumors respond favorably to hormonal manipulation. The selective estrogen…”
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Dissertation