Search Results - "Belcheva, Elitza"
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1
Sotatercept analog suppresses inflammation to reverse experimental pulmonary arterial hypertension
Published in Scientific reports (12-05-2022)“…Sotatercept is an activin receptor type IIA-Fc (ActRIIA-Fc) fusion protein that improves cardiopulmonary function in patients with pulmonary arterial…”
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Journal Article -
2
The orphan ligand, activin C, signals through activin receptor-like kinase 7
Published in eLife (23-06-2022)“…Activin ligands are formed from two disulfide-linked inhibin β (Inhβ) subunit chains. They exist as homodimeric proteins, as in the case of activin A (ActA;…”
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Journal Article -
3
ActRIIB:ALK4-Fc alleviates muscle dysfunction and comorbidities in murine models of neuromuscular disorders
Published in The Journal of clinical investigation (15-02-2021)“…Patients with neuromuscular disorders suffer from a lack of treatment options for skeletal muscle weakness and disease comorbidities. Here, we introduce as a…”
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Journal Article