Search Results - "Bekkers, Ruud LM"

Phenotype-guided targeted therapy based on functional signal transduction pathway activity in recurrent ovarian cancer patients: The STAPOVER study protocol by van der Ploeg, Phyllis, Hendrikse, Cynthia SE, Thijs, Anna MJ, Westgeest, Hans M., Smedts, Huberdina PM, Vos, M Caroline, Jalving, Mathilde, Lok, Christianne AR, Boere, Ingrid A., van Ham, Maaike APC, Ottevanger, Petronella B., Westermann, Anneke M., Mom, Constantijne H., Lalisang, Roy I., Lambrechts, Sandrina, Bekkers, Ruud LM, Piek, Jurgen MJ

“…Ovarian cancer is the fifth cause of cancer-related death among women. The benefit of targeted therapy for ovarian cancer patients is limited even if treatment…”
Get full text

Survival of patients with early-stage cervical cancer after abdominal or laparoscopic radical hysterectomy: a nationwide cohort study and literature review by Wenzel, Hans H.B., Smolders, Ramon G.V., Beltman, Jogchum J., Lambrechts, Sandrina, Trum, Hans W., Yigit, Refika, Zusterzeel, Petra L.M., Zweemer, Ronald P., Mom, Constantijne H., Bekkers, Ruud L.M., Lemmens, Valery E.P.P., Nijman, Hans W., Van der Aa, Maaike A.

“…Recently, the safety of laparoscopic radical hysterectomy (LRH) has been called into question in early-stage cervical cancer. This study aimed to evaluate…”
Get full text

Effects of a combined exercise and dietary intervention on body composition, physical functioning and fatigue in patients with ovarian cancer: results of the PADOVA trial by Kenkhuis, Marlou-Floor, Stelten, Stephanie, Hartman, Yvonne AW, Brouwer, Calvin G., ten Tusscher, Marieke R., van Lonkhuijzen, Luc RCW, Kenter, Gemma G., van Driel, Willemien J., Winkels, Renate M., Bekkers, Ruud LM, Ottevanger, Nelleke PB, Hoedjes, Meeke, Buffart, Laurien M.

“…Background Guidelines recommend to include exercise and dietary advice in standard care for patients with cancer, based on evidence primarily derived from…”
Get full text

Identification and Validation of a 3-Gene Methylation Classifier for HPV-Based Cervical Screening on Self-Samples by Verlaat, Wina, Snoek, Barbara C, Heideman, Daniëlle A M, Wilting, Saskia M, Snijders, Peter J F, Novianti, Putri W, van Splunter, Annina P, Peeters, Carel F W, van Trommel, Nienke E, Massuger, Leon F A G, Bekkers, Ruud L M, Melchers, Willem J G, van Kemenade, Folkert J, Berkhof, Johannes, van de Wiel, Mark A, Meijer, Chris J L M, Steenbergen, Renske D M

“…Offering self-sampling of cervico-vaginal material for high-risk human papillomavirus (hrHPV) testing is an effective method to increase the coverage in…”
Get full text

Oral contraceptive and intrauterine device use and the risk of cervical intraepithelial neoplasia grade III or worse: a population-based study by Loopik, Diede L., IntHout, Joanna, Melchers, Willem J.G., Massuger, Leon F.A.G., Bekkers, Ruud L.M., Siebers, Albert G.

“…Hormonal contraceptive use has been associated with the development of cervical cancer, although inconsistent results are reported on the association with…”
Get full text

Increased association of ovarian cancer in women with histological proven endosalpingiosis by Hermens, Marjolein, van Altena, Anne M., Bulten, Johan, Siebers, Albert G., Bekkers, Ruud L.M.

“…•Histological proven endosalpingiosis is associated with ovarian cancer.•This association is independent of concurrent histological endometriosis.•Pathologist…”
Get full text

Evaluation of p16/Ki-67 dual-stained cytology as triage test for high-risk human papillomavirus-positive women by Ebisch, Renée MF, van der Horst, Judith, Hermsen, Meyke, Rijstenberg, L Lucia, Vedder, Judith EM, Bulten, Johan, Bosgraaf, Remko P, Verhoef, Viola MJ, Heideman, Daniëlle AM, Snijders, Peter JF, Meijer, Chris JLM, van Kemenade, Folkert J, Massuger, Leon FAG, Melchers, Willem JG, Bekkers, Ruud LM, Siebers, Albert G

“…The aim of this study was to evaluate the clinical utility of p16/Ki-67 dual staining, for the identification of CIN in high-risk HPV-positive women from a…”
Get full text

Reasons for non-attendance to cervical screening and preferences for HPV self-sampling in Dutch women by Bosgraaf, Remko P, Ketelaars, Pleun J.W, Verhoef, Viola M.J, Massuger, Leon F.A.G, Meijer, Chris J.L.M, Melchers, Willem J.G, Bekkers, Ruud L.M

“…Abstract Objectives High attendance rates in cervical screening are essential for effective cancer prevention. Offering HPV self-sampling to non-responders…”
Get full text

Comparative performance of novel self‐sampling methods in detecting high‐risk human papillomavirus in 30,130 women not attending cervical screening by Bosgraaf, Remko P., Verhoef, Viola M.J., Massuger, Leon F.A.G., Siebers, Albert G., Bulten, Johan, de Kuyper‐de Ridder, Gabriëlle M., Meijer, Chris J.M., Snijders, Peter J.F., Heideman, Daniëlle A.M., IntHout, Joanna, van Kemenade, Folkert J., Melchers, Willem J.G., Bekkers, Ruud L.M.

“…We determined whether the participation rate for a brush‐based cervicovaginal self‐sampling device is noninferior to the participation rate for a lavage‐based…”
Get full text

Triage of high-risk HPV positive women in cervical cancer screening by Ebisch, Renée MF, Siebers, Albert G, Bosgraaf, Remko P, Massuger, Leon FAG, Bekkers, Ruud LM, Melchers, Willem JG

“…Introduction: High-risk human papillomavirus (hrHPV) testing is expected to replace cytology as primary screening method for cervical cancer screening in an…”
Get full text

Pretreatment retroperitoneal para-aortic lymph node staging in advanced cervical cancer: a review by Smits, Roos Marthe, Zusterzeel, Petra L M, Bekkers, Ruud L M

“…The aims of this study were to evaluate the safety and impact of pretreatment surgical para-aortic lymph node staging (PALNS) in advanced cervical cancer…”
Get more information

Authors' reply re: Reflex cytology for triage of high‐risk human‐papillomavirus‐positive self‐sampled material in cervical cancer screening: a prospective cohort study by Loopik, Diede L, Melchers, Willem JG, Vedder, Judith EM, Brule, Adriaan JC, Massuger, Leon FAG, Bekkers, Ruud LM, Siebers, Albert G

Get full text

Vaginal Radical Trachelectomy for Early-Stage Cervical Cancer: Increased Recurrence Risk for Adenocarcinoma by Zusterzeel, Petra L M, Pol, Fraukje J M, van Ham, Maaike, Zweemer, Ronald P, Bekkers, Ruud L M, Massuger, Leon F A G, Verheijen, René H M

“…To evaluate consecutive vaginal radical trachelectomies (VRTs) in early-stage cervical cancer in the 2 main referral centers for fertility-preserving surgery…”
Get more information

The role of genotype‐specific human papillomavirus detection in diagnosing residual cervical intraepithelial neoplasia by Bekkers, Ruud LM, Melchers, Willem JG, Bakkers, Judith MJE, Hanselaar, Antonius GJM, Quint, Wim GV, Boonstra, Henk, Massuger, Leon FAG

“…We assessed prospectively whether residual cervical intraepithelial neoplasia (CIN) after treatment for high‐grade CIN can be predicted by genotype‐specific…”
Get full text

The clinical value of HPV genotyping in triage of women with high‐risk‐HPV‐positive self‐samples by Ebisch, Renée M.F., de Kuyper–de Ridder, Gabriëlle M., Bosgraaf, Remko P., Massuger, Leon F.A.G., IntHout, Joanna, Verhoef, Viola M.J., Heideman, Daniëlle A.M., Snijders, Peter J.F., Meijer, Chris J.L.M., van Kemenade, Folkert J., Bulten, Johan, Siebers, Albert G., Bekkers, Ruud L.M., Melchers, Willem J.G.

“…Cytology alone, or combined with HPV16/18 genotyping, might be an acceptable method for triage in hrHPV‐cervical cancer screening. Previously studied…”
Get full text

Long-term risk of endometrial cancer following postmenopausal bleeding and reassuring endometrial biopsy by Visser, Nicole C M, Sparidaens, Ellen M, van den Brink, Jan-Willem, Breijer, Maria C, Boss, Erik A, Veersema, Sebastiaan, Siebers, Albert G, Bulten, Johan, Pijnenborg, Johanna M A, Bekkers, Ruud L M

“…Women with postmenopausal bleeding and endometrial thickness >4 mm undergo endometrial sampling to exclude endometrial cancer. The aim of this study is to…”
Get more information

Periconceptional folic acid intake in Nijmegen, Netherlands by Bekkers, Ruud LM, Eskes, Tom KAB

“…Researchers believe that a joint sustained effort among health authorities, the media and health-care professionals can lead to an increased folic acid intake…”
Get full text

Factors attributing to the failure of endometrial sampling in women with postmenopausal bleeding by Visser, Nicole C M, Breijer, Maria C, Herman, Malou C, Bekkers, Ruud L M, Veersema, Sebastiaan, Opmeer, Brent C, Mol, Ben W J, Timmermans, Anne, Pijnenborg, Johanna M A

“…To determine which doctor- and patient-related factors affect failure of outpatient endometrial sampling in women with postmenopausal bleeding, and to develop…”
Get more information

Clinically applied procedures for human ovarian tissue cryopreservation result in different levels of efficacy and efficiency by Bastings, Lobke, Westphal, Johan R., Beerendonk, Catharina C. M., Bekkers, Ruud L. M., Zusterzeel, Petra L. M., Hendriks, Jan C. M., Braat, Didi D. M., Peek, Ronald

“…Purpose Different protocols are being used worldwide for the cryopreservation of human ovarian tissue for fertility preservation purposes. The efficiency and…”
Get full text

Co-administration of human papillomavirus-16/18 AS04-adjuvanted vaccine with hepatitis B vaccine: Randomized study in healthy girls by Schmeink, Channa E, Bekkers, Ruud L.M, Josefsson, Ann, Richardus, Jan H, Berndtsson Blom, Katarina, David, Marie-Pierre, Dobbelaere, Kurt, Descamps, Dominique

“…Highlights ► Co-administration of HPV-16/18 AS04-adjuvanted vaccine and hepatitis B vaccine. ► Did not interfere with the immune response to HPV-16/18…”
Get full text