Search Results - "Bekhit, Adnan A."
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1
Keratin: dissolution, extraction and biomedical application
Published in Biomaterials science (22-08-2017)“…Keratinous materials such as wool, feathers and hooves are tough unique biological co-products that usually have high sulfur and protein contents. A high…”
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2
New heterocyclic hybrids of pyrazole and its bioisosteres: Design, synthesis and biological evaluation as dual acting antimalarial-antileishmanial agents
Published in European journal of medicinal chemistry (13-04-2015)“…A new series of pyrazole derivatives were synthesized by hybridization with five-membered heterocyclic moieties such as thiazoles, thiazolidinones,…”
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3
Marine Fish-Derived Lysophosphatidylcholine: Properties, Extraction, Quantification, and Brain Health Application
Published in Molecules (Basel, Switzerland) (30-03-2023)“…Long-chain omega-3 fatty acids esterified in lysophosphatidylcholine (LPC-omega-3) are the most bioavailable omega-3 fatty acid form and are considered…”
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4
Design, synthesis and biological evaluation of some pyrazole derivatives as anti-inflammatory-antimicrobial agents
Published in Bioorganic & medicinal chemistry (15-04-2004)“…The synthesis of novel series of structurally related 1 H-pyrazolyl derivatives is described. All the newly synthesized compounds were tested for their in vivo…”
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5
Pyrazoles as promising scaffold for the synthesis of anti-inflammatory and/or antimicrobial agent: a review
Published in Mini reviews in medicinal chemistry (01-10-2010)“…There has been a considerable interest in the development of novel compounds with anti-inflammatory and /or antimicrobial activities. Several economical and…”
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6
Synthesis and antidiabetic activity of novel triazole derivatives containing amino acids
Published in Journal of heterocyclic chemistry (01-06-2020)“…New series of triazole derivatives coupled with amino acids 1a‐h were obtained via multicomponent reaction of 2‐hydroxy benzaldehyde or 2‐hydroxy acetophenone…”
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Spiro heterocycles bearing piperidine moiety as potential scaffold for antileishmanial activity: synthesis, biological evaluation, and in silico studies
Published in Journal of enzyme inhibition and medicinal chemistry (01-12-2023)“…New spiro-piperidine derivatives were synthesised via the eco-friendly ionic liquids in a one-pot fashion. The in vitro antileishmanial activity against…”
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8
New pyrazolylpyrazoline derivatives as dual acting antimalarial-antileishamanial agents: synthesis, biological evaluation and molecular modelling simulations
Published in Journal of enzyme inhibition and medicinal chemistry (31-12-2022)“…Promising inhibitory activities of the parasite multiplication were obtained upon evaluation of in vivo antimalarial activities of new pyrazolylpyrazoline…”
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9
Methotrexate-Lactoferrin Targeted Exemestane Cubosomes for Synergistic Breast Cancer Therapy
Published in Frontiers in chemistry (22-03-2022)“…While the treatment regimen of certain types of breast cancer involves a combination of hormonal therapy and chemotherapy, the outcomes are limited due to the…”
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10
Supporting SARS-CoV-2 Papain-Like Protease Drug Discovery: In silico Methods and Benchmarking
Published in Frontiers in chemistry (05-11-2020)“…The coronavirus disease 19 (COVID-19) is a rapidly growing pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Its papain-like…”
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11
Antimalarial and Antileishmanial Flavonoids from Calendula officinalis Flowers
Published in Agronomy (Basel) (01-11-2023)“…Calendula officinalis L. (Asteraceae), commonly known as English or pot marigold, is an herbaceous plant with edible flowers. In this study, UPLC-ESI-MS/MS…”
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12
Novel Synthesis of Titanium Oxide Nanoparticles: Biological Activity and Acute Toxicity Study
Published in Bioinorganic chemistry and applications (2021)“…Titanium oxide nanoparticles (TiO2 NPs) have been attracting numerous research studies due to their activity; however, there is a growing concern about the…”
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13
Sequential Delivery of Novel Triple Drug Combination via Crosslinked Alginate/Lactoferrin Nanohybrids for Enhanced Breast Cancer Treatment
Published in Pharmaceutics (01-11-2022)“…While breast cancer remains a global health concern, the elaboration of rationally designed drug combinations coupled with advanced biocompatible delivery…”
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14
Synthesis and Preliminary Biological Evaluation of 1,3,5-Triazine Amino Acid Derivatives to Study Their MAO Inhibitors
Published in Molecules (Basel, Switzerland) (02-09-2015)“…Three series of 4,6-dimethoxy-, 4,6-dipiperidino- and 4,6-dimorpholino-1,3,5-triazin-2-yl) amino acid derivatives were synthesized and characterized. A…”
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15
Compounds Containing Azole Scaffolds as Cyclooxygenase Inhibitors: A Review
Published in Current topics in medicinal chemistry (01-12-2016)“…There has been considerable interest in azole-containing compounds as promising antiinflammatory agents. Designed compounds with five-membered…”
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16
PHNQ from Evechinus chloroticus Sea Urchin Supplemented with Calcium Promotes Mineralization in Saos-2 Human Bone Cell Line
Published in Marine drugs (19-07-2020)“…Polyhydroxylated naphthoquinones (PHNQs), known as spinochromes that can be extracted from sea urchins, are bioactive compounds reported to have medicinal…”
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17
Combined Cancer Immunotheranostic Nanomedicines: Delivery Technologies and Therapeutic Outcomes
Published in ACS omega (07-02-2023)“…Cancer is among the main causes of mortality all over the world. The delayed diagnosis is directly related to the decrease in survival rate. The use of…”
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18
Polyphenol uses in biomaterials engineering
Published in Biomaterials (01-06-2018)“…Polyphenols are micronutrients obtained from diet that have been suggested to play an important role in health. The health benefits of polyphenols and their…”
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Tetrazolo[1,5- a]quinoline as a potential promising new scaffold for the synthesis of novel anti-inflammatory and antibacterial agents
Published in European journal of medicinal chemistry (01-03-2004)“…Three series of tetrazolo[1,5- a]quinoline derivatives have been synthesized. The first series was synthesized starting by the condensation of tetrazolo[1,5-…”
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Novel Pyrazole Derivatives as Potential Promising Anti-inflammatory Antimicrobial Agents
Published in Archiv der Pharmazie (Weinheim) (01-04-2005)“…Four series of 1H‐pyrazole derivatives have been synthesized. The first series was synthesized starting by condensing the hydrazine derivatives 1a–d with…”
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