Search Results - "Beitzinger, Michaela"
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siPools: highly complex but accurately defined siRNA pools eliminate off-target effects
Published in Nucleic acids research (08-07-2014)“…Short interfering RNAs (siRNAs) are widely used as tool for gene inactivation in basic research and therapeutic applications. One of the major shortcomings of…”
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Experimental identification of microRNA targets by immunoprecipitation of Argonaute protein complexes
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2011)“…MicroRNAs (miRNAs) represent a class of small noncoding RNAs that negatively regulate gene expression-. Intensive research during the past decade has…”
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3
Identification of Human microRNA Targets From Isolated Argonaute Protein Complexes
Published in RNA biology (01-04-2007)“…MicroRNAs (miRNAs) constitute a class of small non-coding RNAs that regulate gene expression on the level of translation and/or mRNA stability. Mammalian…”
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miR-181a Modulation of ERK-MAPK Signaling Sustains DC-SIGN Expression and Limits Activation of Monocyte-Derived Dendritic Cells
Published in Cell reports (Cambridge) (17-03-2020)“…DC-SIGN+ monocyte-derived dendritic cells (mo-DCs) play important roles in bacterial infections and inflammatory diseases, but the factors regulating their…”
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5
p53 family members in myogenic differentiation and rhabdomyosarcoma development
Published in Cancer cell (01-10-2006)“…The p53 family comprises the tumor suppressor p53 and the structural homologs p63 and p73. How the three family members cooperate in tumor suppression remains…”
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6
p73 poses a barrier to malignant transformation by limiting anchorage-independent growth
Published in The EMBO journal (05-03-2008)“…p53 is known to prevent tumour formation by restricting the proliferation of damaged or oncogene‐expressing cells. In contrast, how the p53 family member p73…”
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Analysis of Argonaute Complex Bound mRNAs in DU145 Prostate Carcinoma Cells Reveals New miRNA Target Genes
Published in Prostate Cancer (01-01-2017)“…Posttranscriptional gene regulation by microRNAs (miRNAs) contributes to the induction and maintenance of prostate carcinoma (PCa). To identify mRNAs enriched…”
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Inactivation of Retinoblastoma (RB) Tumor Suppressor by Oncogenic Isoforms of the p53 Family Member p73
Published in The Journal of biological chemistry (18-04-2003)“…The p53 family includes three members that share significant sequence homology, yet exhibit fundamentally different functions in tumorigenesis. Whereas p53…”
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MicroRNAs: From Decay to Decoy
Published in Cell (05-03-2010)“…MicroRNAs interact with Argonaute proteins to guide posttranscriptional gene silencing. Eiring et al. (2010) now show that miR-328 has a second function,…”
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10
Lithium chloride effectively kills the honey bee parasite Varroa destructor by a systemic mode of action
Published in Scientific reports (12-01-2018)“…Honey bees are increasingly important in the pollination of crops and wild plants. Recent reports of the weakening and periodical high losses of managed honey…”
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11
A Human snoRNA with MicroRNA-Like Functions
Published in Molecular cell (21-11-2008)“…Small noncoding RNAs function in concert with Argonaute (Ago) proteins to regulate gene expression at the level of transcription, mRNA stability, or…”
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Systematic Analysis of Viral and Cellular MicroRNA Targets in Cells Latently Infected with Human γ-Herpesviruses by RISC Immunoprecipitation Assay
Published in Cell host & microbe (22-04-2010)“…The mRNA targets of microRNAs (miRNAs) can be identified by immunoprecipitation of Argonaute (Ago) protein-containing RNA-induced silencing complexes (RISCs)…”
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Author Correction: Lithium chloride effectively kills the honey bee parasite Varroa destructor by a systemic mode of action
Published in Scientific reports (06-03-2018)“…A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper…”
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14
The small RNA expression profile of the developing murine urinary and reproductive systems
Published in FEBS letters (05-11-2010)“…microRNAs (miRNAs) are small non-coding RNAs with fundamental roles in the regulation of gene expression. miRNAs assemble with Argonaute (Ago) proteins to…”
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15
C-terminal diversity within the p53 family accounts for differences in DNA binding and transcriptional activity
Published in Nucleic acids research (01-04-2008)“…The p53 family is known as a family of transcription factors with functions in tumor suppression and development. Whereas the central DNA-binding domain is…”
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Preview. MicroRNAs: from decay to decoy
Published in Cell (05-03-2010)“…MicroRNAs interact with Argonaute proteins to guide posttranscriptional gene silencing. Eiring et al. (2010) now show that miR-328 has a second function,…”
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