Search Results - "Beirão, P S L"

A new family of small (4kDa) neurotoxins from the venoms of spiders of the genus Phoneutria by Lúcio, A D, Campos, F V, Richardson, M, Cordeiro, M N, Mazzoni, M S C, de Lima, M E, Pimenta, M C, Bemquerer, M P, Figueiredo, S G, Gomes, P C, Beirão, P S L

“…A family of 4kDa neurotoxic peptides was purified from venoms of Phoneutria spiders. All have six cysteine residues, and low similarity with other neurotoxins…”
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Frontoxins, three-finger toxins from Micrurus frontalis venom, decrease miniature endplate potential amplitude at frog neuromuscular junction by Moreira, K.G., Prates, M.V., Andrade, F.A.C., Silva, L.P., Beirão, P.S.L., Kushmerick, C., Naves, L.A., Bloch, C.

“…Neurotoxicity is a major symptom of envenomation caused by Brazilian coral snake Micrurus frontalis. Due to the small amount of material that can be collected,…”
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Is there a role for voltage-gated Na+ channels in the aggressiveness of breast cancer? by Rhana, P, Trivelato, Junior, R R, Beirão, P S L, Cruz, J S, Rodrigues, A L P

“…Breast cancer is the most common cancer among women and its metastatic potential is responsible for numerous deaths. Thus, the need to find new targets for…”
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A toxin from the spider Phoneutria nigriventer that blocks calcium channels coupled to exocytosis by Guatimosim, C., Romano‐Silva, M. A., Cruz, J. S., Beirão, P. S. L., Kalapothakis, E., Moraes‐Santos, T., Cordeiro, M. N., Diniz, C. R., Gomez, M. V., Prado, M. A. M.

“…1 The aim of the present experiments was to investigate the pharmacological action of a toxin from the spider Phoneutria nigriventer, Tx3‐3, on the function of…”
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Regulation of the glutamate uptake by extracellular calcium by Mafra, R.A., de Oliveira, L.C., Ferreira, C.A.G., De Lima, M.E., Beirão, P.S.L., Cruz, J.S.

“…To determine whether [Ca 2+] e modulates glutamate re-uptake, we studied the uptake mechanism into rat cerebrocortical synaptosomes. The removal of…”
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Phoneutria nigriventer Toxin Tx3‐1 Blocks A‐Type K+ Currents Controlling Ca2+ Oscillation Frequency in GH3 Cells by Kushmerick, C., Kalapothakis, E., Beirão, P. S. L., Penaforte, C. L., Prado, V. F., Cruz, J. S., Diniz, C. R., Cordeiro, M. N., Gomez, M. V., Romano‐Silva, M. A., Prado, M. A. M.

“…: GH3 cells present spontaneous Ca2+ action potentials and oscillations of intracellular Ca2+, which can be modified by altering the activity of K+ or Ca2+…”
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CaV 3.1 and CaV 3.3 account for T-type Ca2+ current in GH3 cells by Mudado, M A, Rodrigues, A L, Prado, V F, Beirão, P S L, Cruz, J S

“…T-type Ca2+ channels are important for cell signaling by a variety of cells. We report here the electrophysiological and molecular characteristics of the…”
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Electrophysiological evidence for glial-subtype glutamate transporter functional expression in rat cerebellar granule neurons by Mafra, R A, Leão, R M, Beirão, P S L, Cruz, J S

“…A glutamate-sensitive inward current (Iglu) is described in rat cerebellar granule neurons and related to a glutamate transport mechanism. We examined the…”
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Comparison of the partial proteomes of the venoms of Brazilian spiders of the genus Phoneutria by Richardson, M., Pimenta, A.M.C., Bemquerer, M.P., Santoro, M.M., Beirao, P.S.L., Lima, M.E., Figueiredo, S.G., Bloch, C., Vasconcelos, E.A.R., Campos, F.A.P., Gomes, P.C., Cordeiro, M.N.

“…The proteomes of the venoms of the Brazilian wandering “armed” spiders Phoneutria nigriventer, Phoneutria reidyi, and Phoneutria keyserlingi, were compared…”
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Phoneutria nigriventer Toxin Tx3‐1 Blocks A‐Type K + Currents Controlling Ca 2+ Oscillation Frequency in GH 3 Cells by Kushmerick, C., Kalapothakis, E., Beirão, P. S. L., Penaforte, C. L., Prado, V. F., Cruz, J. S., Diniz, C. R., Cordeiro, M. N., Gomez, M. V., Romano‐Silva, M. A., Prado, M. A. M.

“…GH 3 cells present spontaneous Ca 2+ action potentials and oscillations of intracellular Ca 2+ , which can be modified by altering the activity of K + or Ca 2+…”
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Inhibition of neuronal high-voltage activated calcium channels by the ω- Phoneutria nigriventer Tx3-3 peptide toxin by Leão, Ricardo M, Cruz, Jader S, Diniz, Carlos R, Cordeiro, Marta N, Beirão, Paulo S.L

“…We have investigated the effect of ω-PnTx3-3 (referred to in previous papers simply as Tx3-3), a peptide toxin from the venom of the spider Phoneutria…”
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Macrophage Damage by Leishmania amazonensis Cytolysin: Evidence of Pore Formation on Cell Membrane by NORONHA, F. S. M, CRUZ, J. S, BEIRAO, P. S. L, HORTA, M. F

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Glutamate transport in rat cerebellar granule cells is impaired by inorganic epileptogenic agents by Mafra, R.A., Araújo, D.A.M., Beirão, P.S.L., Cruz, J.S.

“…There is evidence that extracellular glutamate levels are elevated in certain brain regions immediately prior to and during induction and propagation of…”
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Cloning, cDNA sequence analysis and patch clamp studies of a toxin from the venom of the armed spider ( Phoneutria nigriventer) by Kalapothakis, E., Penaforte, C.L., Leão, R.M., Cruz, J.S., Prado, V.F., Cordeiro, M.N., Diniz, C.R., Romano-Silva, M.A., Prado, M.A.M., Gomez, M.V., Beirão, P.S.L.

“…The cDNAs ( Tx3-2 and Pn3A) encoding precursor of toxin Tx3-2 and an isoform called Pn3A have been isolated from a library constructed from stimulated venom…”
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Effects of a toxic fraction, PhTx2, from the spider Phoneutria nigriventer on the sodium current by ARAUJO, D. A. M, CORDEIRO, M. N, DINIZ, C. R, BEIRAO, P. S. L

“…The toxic fraction PhTx2 of the spider Phoneutria nigriventer was studied with a modified loose patch clamp technique on frog skeletal muscle. At saturating…”
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Cloning of cDNAs encoding neurotoxic peptides from the spider Phoneutria nigriventer by Kalapothakis, Evanguedes, Penaforte, Claudia L, Beirão, Paulo S.L, Romano-Silva, Marco A, Cruz, Jader S, Prado, Marco A.M, Guimarães, Pedro E.M, Gomez, Marcus V, Prado, Vania F

“…A cDNA library made from venom glands of the spider Phoneutria nigriventer was constructed and used to clone neurotoxic peptides. A cDNA of about 360…”
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Tityustoxin effect on nerve compound action potentials requires extracellular sodium by Cruz, J.S., Matavel, A.C.S., Leão-Filho, H.M., Moraes-Santos, T., Beirão, P.S.L.

“…Previous studies have demonstrated that Li + ions can substitute for Na + in a variety of functional systems. Using the single sucrose-gap recording technique,…”
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Inactivating 'ball' peptide from Shaker B blocks Ca2+-activated but not ATP-dependent K+ channels of rat skeletal muscle by BEIRAO, P. S. L, DAVIES, N. W, STANFIELD, P. R

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Reversion by polyclonal antibodies of α effects of Tityus serrulatus venom on frog sciatic nerve by Silveira, Josianne N., Heneine, Ibrahim F., Beirão, Paulo S.L.

“…Fraction T 2 from Tityus serrulatus venom produced a marked lengthening of action potentials recorded with the single sucrose-gap technique, a characteristic…”
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Effects of crotoxin on the action potential kinetics of frog skeletal muscle by Araújo, D A, Beirão, P S

“…1. The effect of crotoxin on the action potential kinetics of frog (Rana catesbeiana; 60-80 g) skeletal muscle was studied using a modified Ringer solution…”
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