Search Results - "Beins, Eva"
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Relationships between neurotransmitter receptor densities and expression levels of their corresponding genes in the human hippocampus
Published in NeuroImage (Orlando, Fla.) (01-06-2023)“…•Receptor density and gene expression data are from the same human hippocampal tissue.•Significant differences in receptor density only found in metabotropic…”
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LAMP-Seq enables sensitive, multiplexed COVID-19 diagnostics using molecular barcoding
Published in Nature biotechnology (01-12-2021)“…Frequent testing of large population groups combined with contact tracing and isolation measures will be crucial for containing Coronavirus Disease 2019…”
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Lack of Cannabinoid Receptor Type-1 Leads to Enhanced Age-Related Neuronal Loss in the Locus Coeruleus
Published in International journal of molecular sciences (22-12-2020)“…Our laboratory and others have previously shown that cannabinoid receptor type-1 (CB1r) activity is neuroprotective and a modulator of brain ageing; a genetic…”
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Cannabinoid receptor 1 signalling modulates stress susceptibility and microglial responses to chronic social defeat stress
Published in Translational psychiatry (15-03-2021)“…Psychosocial stress is one of the main environmental factors contributing to the development of psychiatric disorders. In humans and rodents, chronic stress is…”
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The interplay between polygenic score for tumor necrosis factor-α, brain structural connectivity, and processing speed in major depression
Published in Molecular psychiatry (01-10-2024)“…Reduced processing speed is a core deficit in major depressive disorder (MDD) and has been linked to altered structural brain network connectivity. Ample…”
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Chemokine receptor 4 expression on blood T lymphocytes predicts severity of major depressive disorder
Published in Journal of affective disorders (01-08-2022)“…Chemokines and their receptors regulate inflammatory processes in major depressive disorder (MDD). Here, we characterize the expression pattern of the C-C…”
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Expression Analysis of CB2-GFP BAC Transgenic Mice
Published in PloS one (25-09-2015)“…The endocannabinoid system (ECS) is a retrograde messenger system, consisting of lipid signaling molecules that bind to at least two G-protein-coupled…”
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Cohort profile: BioMD-Y (biopsychosocial factors of major depression in youth) – a biobank study on the molecular genetics and environmental factors of depression in children and adolescents in Munich
Published in BMJ open (13-03-2024)“…PurposeBioMD-Y is a comprehensive biobank study of children and adolescents with major depression (MD) and their healthy peers in Germany, collecting a host of…”
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Efficacy of Δ9 -Tetrahydrocannabinol (THC) Alone or in Combination With a 1:1 Ratio of Cannabidiol (CBD) in Reversing the Spatial Learning Deficits in Old Mice
Published in Frontiers in aging neuroscience (30-08-2021)“…Decline in cognitive performance, an aspect of the normal aging process, is influenced by the endocannabinoid system (ECS). Cannabinoid receptor 1 (CB1)…”
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Bidirectional Effect of Long-Term Δ 9 -Tetrahydrocannabinol Treatment on mTOR Activity and Metabolome
Published in ACS pharmacology & translational science (13-09-2024)“…Brain aging is associated with cognitive decline, reduced synaptic plasticity, and altered metabolism. The activity of mechanistic target of rapamycin (mTOR)…”
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Analogous modulation of inflammatory responses by the endocannabinoid system in periodontal ligament cells and microglia
Published in Head & face medicine (16-11-2020)“…Abstract Background Periodontal ligament (PDL) cells initiate local immune responses, similar to microglia regulating primary host defense mechanisms in…”
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Characterization of inflammatory markers and transcriptome profiles of differentially activated embryonic stem cell-derived microglia
Published in Glia (01-06-2016)“…Microglia, the immune cells of the CNS, are highly adaptive cells that can acquire different pro‐ and anti‐inflammatory activation states with distinct…”
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Genetic and functional analyses implicate microRNA 499A in bipolar disorder development
Published in Translational psychiatry (07-10-2022)“…Bipolar disorder (BD) is a complex mood disorder with a strong genetic component. Recent studies suggest that microRNAs contribute to psychiatric disorder…”
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Author Correction: LAMP-Seq enables sensitive, multiplexed COVID-19 diagnostics using molecular barcoding
Published in Nature biotechnology (01-08-2022)Get full text
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Bidirectional Effect of Long-Term Δ9‑Tetrahydrocannabinol Treatment on mTOR Activity and Metabolome
Published in ACS pharmacology & translational science (13-09-2024)“…Brain aging is associated with cognitive decline, reduced synaptic plasticity, and altered metabolism. The activity of mechanistic target of rapamycin (mTOR)…”
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Dendritic Cells: Neglected Modulators of Peripheral Immune Responses and Neuroinflammation in Mood Disorders?
Published in Cells (Basel, Switzerland) (19-04-2021)“…Affective disorders (AD) including major depressive disorder (MDD) and bipolar disorder (BD) are common mood disorders associated with increased disability and…”
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Cannabinoid 1 Receptor Signaling on Hippocampal GABAergic Neurons Influences Microglial Activity
Published in Frontiers in molecular neuroscience (28-08-2018)“…Microglia, the resident immune cells of the brain, play important roles in defending the brain against pathogens and supporting neuronal circuit plasticity…”
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Pharmacological blockade of cannabinoid receptor 2 signaling does not affect LPS/IFN-γ-induced microglial activation
Published in Scientific reports (10-07-2023)“…Cannabinoid receptor 2 (CB2) signaling modulates microglial responses to inflammatory stimuli. Our previous studies demonstrated that genetic deletion of CB2…”
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Author Correction: Pharmacological blockade of cannabinoid receptor 2 signaling does not affect LPS/IFN-γ-induced microglial activation
Published in Scientific reports (21-09-2023)Get full text
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Correction: Expression Analysis of CB2-GFP BAC Transgenic Mice
Published in PloS one (17-12-2015)Get full text
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