Search Results - "Bein, Keith"

The Effects of Chronic Exposure to Ambient Traffic-Related Air Pollution on Alzheimer's Disease Phenotypes in Wildtype and Genetically Predisposed Male and Female Rats by Patten, Kelley T, Valenzuela, Anthony E, Wallis, Christopher, Berg, Elizabeth L, Silverman, Jill L, Bein, Keith J, Wexler, Anthony S, Lein, Pamela J

“…Epidemiological data link traffic-related air pollution (TRAP) to increased risk of Alzheimer's disease (AD). Preclinical data corroborating this association…”
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Ambient particulate matter activates the aryl hydrocarbon receptor in dendritic cells and enhances Th17 polarization by Castañeda, Alejandro R., Pinkerton, Kent E., Bein, Keith J., Magaña-Méndez, Alfonso, Yang, Houa T., Ashwood, Paul, Vogel, Christoph F.A.

“…[Display omitted] •Air pollution PM can shape CD4+ T cell immune responses via the AhR in DCs.•PAHs in PM activate the AhR in DCs.•PM enhances DC activation by…”
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Pathological Cardiopulmonary Evaluation of Rats Chronically Exposed to Traffic-Related Air Pollution by Edwards, Sabrina, Zhao, Gang, Tran, Joanne, Patten, Kelley T, Valenzuela, Anthony, Wallis, Christopher, Bein, Keith J, Wexler, Anthony S, Lein, Pamela J, Rao, Xiaoquan

“…Traffic-related air pollution (TRAP) is made up of complex mixtures of particulate matter, gases and volatile compounds. However, the effects of TRAP on the…”
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Seasonal variations in photooxidant formation and light absorption in aqueous extracts of ambient particles by Ma, Lan, Worland, Reed, Heinlein, Laura, Guzman, Chrystal, Jiang, Wenqing, Niedek, Christopher, Bein, Keith J, Zhang, Qi, Anastasio, Cort

“…Fog/cloud drops and aerosol liquid water are important sites for the transformations of atmospheric species, largely through reactions with photoformed…”
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Predicting photooxidant concentrations in aerosol liquid water based on laboratory extracts of ambient particles by Ma, Lan, Worland, Reed, Jiang, Wenqing, Niedek, Christopher, Guzman, Chrystal, Bein, Keith J, Zhang, Qi, Anastasio, Cort

“…Aerosol liquid water (ALW) is a unique reaction medium, but its chemistry is poorly understood. For example, little is known of photooxidant concentrations –…”
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Photooxidants from brown carbon and other chromophores in illuminated particle extracts by Kaur, Richie, Labins, Jacqueline R, Helbock, Scarlett S, Jiang, Wenqing, Bein, Keith J, Zhang, Qi, Anastasio, Cort

“…While photooxidants are important in atmospheric condensed phases, there are very few measurements in particulate matter (PM). Here we measure light absorption…”
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Fine particulate matter (PM2.5) enhances allergic sensitization in BALB/c mice by Castañeda, Alejandro R., Bein, Keith J., Smiley-Jewell, Suzette, Pinkerton, Kent E.

“…Ambient particulate matter (PM), a component of air pollution, exacerbates airway inflammation and hyperreactivity in asthmatic patients. Studies showed that…”
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Effects of early life exposure to traffic-related air pollution on brain development in juvenile Sprague-Dawley rats by Patten, Kelley T., González, Eduardo A., Valenzuela, Anthony, Berg, Elizabeth, Wallis, Christopher, Garbow, Joel R., Silverman, Jill L., Bein, Keith J., Wexler, Anthony S., Lein, Pamela J.

“…Epidemiological studies link traffic-related air pollution (TRAP) to increased risk for various neurodevelopmental disorders (NDDs); however, there are limited…”
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Emulating Near-Roadway Exposure to Traffic-Related Air Pollution via Real-Time Emissions from a Major Freeway Tunnel System by Bein, Keith J., Wallis, Chris D., Silverman, Jill L., Lein, Pamela J., Wexler, Anthony S.

“…Epidemiological and toxicological studies continue to demonstrate correlative and causal relationships between exposure to traffic-related air pollution and…”
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In vivo and in vitro inflammatory responses to fine particulate matter (PM2.5) from China and California by Yuan, Wanjun, Fulgar, Ciara C., Sun, Xiaolin, Vogel, Christoph F.A., Wu, Ching-Wen, Zhang, Qi, Bein, Keith J., Young, Dominique E., Li, Wei, Wei, Haiying, Pinkerton, Kent E.

“…[Display omitted] •Time lag effects following an acute exposure to three PM samples were evaluated.•All three PM samples induced acute, but transient…”
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TH17-Induced Neutrophils Enhance the Pulmonary Allergic Response Following BALB/c Exposure to House Dust Mite Allergen and Fine Particulate Matter From California and China by Zhang, Jingjing, Fulgar, Ciara C, Mar, Tiffany, Young, Dominique E, Zhang, Qi, Bein, Keith J, Cui, Liangliang, Castañeda, Alejandro, Vogel, Christoph F A, Sun, Xiaolin, Li, Wei, Smiley-Jewell, Suzette, Zhang, Zunzhen, Pinkerton, Kent E

“…Abstract Asthma is a global and increasingly prevalent disease. According to the World Health Organization, approximately 235 million people suffer from…”
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Hippocampal but Not Serum Cytokine Levels Are Altered by Traffic-Related Air Pollution in TgF344-AD and Wildtype Fischer 344 Rats in a Sex- and Age-Dependent Manner by Patten, Kelley T, Valenzuela, Anthony E, Wallis, Christopher, Harvey, Danielle J, Bein, Keith J, Wexler, Anthony S, Gorin, Fredric A, Lein, Pamela J

“…Epidemiological studies have demonstrated that air pollution is a significant risk factor for age-related dementia, including Alzheimer's disease (AD). It has…”
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Differential pulmonary effects of wintertime California and China particulate matter in healthy young mice by Sun, Xiaolin, Wei, Haiying, Young, Dominique E., Bein, Keith J., Smiley-Jewell, Suzette M., Zhang, Qi, Fulgar, Ciara Catherine B., Castañeda, Alejandro R., Pham, Alexa K., Li, Wei, Pinkerton, Kent E.

“…[Display omitted] Lung toxicity testing for PM2.5 samples, on an equal mass basis, collected during the winter-time from urban regions of China and California…”
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Short-term and repeated exposure to particulate matter sizes from Imperial Valley, California to induce inflammation and asthmatic-like symptoms in mice by D'Evelyn, Savannah M., Bein, Keith J., Laing, Emilia A., Nyguen, Tran, Wu, Ching-Wen, Zhang, Qi, Pinkerton, Kent E.

“…Imperial Valley, California has become increasingly hot, dry, and polluted over the past decade. Particulate matter (PM) levels are amongst the highest in this…”
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AHR Signaling Interacting with Nutritional Factors Regulating the Expression of Markers in Vascular Inflammation and Atherogenesis by Dahlem, Carla, Kado, Sarah Y, He, Yi, Bein, Keith, Wu, Dalei, Haarmann-Stemmann, Thomas, Kado, Norman Y, Vogel, Christoph F A

“…There is strong evidence that exposure to fine particulate matter (PM ) and a high-fat diet (HFD) increase the risk of mortality from atherosclerotic…”
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Biological dose response to PM2.5: effect of particle extraction method on platelet and lung responses by Van Winkle, Laura S, Bein, Keith, Anderson, Donald, Pinkerton, Kent E, Tablin, Fern, Wilson, Dennis, Wexler, Anthony S

“…Particulate matter (PM) exposure contributes to respiratory diseases and cardiopulmonary mortality. PM toxicity is related to sources and composition, such as…”
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Developmental exposure to near roadway pollution produces behavioral phenotypes relevant to neurodevelopmental disorders in juvenile rats by Berg, Elizabeth L., Pedersen, Lauren R., Pride, Michael C., Petkova, Stela P., Patten, Kelley T., Valenzuela, Anthony E., Wallis, Christopher, Bein, Keith J., Wexler, Anthony, Lein, Pamela J., Silverman, Jill L.

“…Epidemiological studies consistently implicate traffic-related air pollution (TRAP) and/or proximity to heavily trafficked roads as risk factors for…”
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Pulmonary health effects of wintertime particulate matter from California and China following repeated exposure and cessation by Yuan, Wanjun, Velasquez, Sandra C., Wu, Ching-Wen, Fulgar, Ciara C., Zhang, Qi, Young, Dominique E., Bein, Keith J., Vogel, Christoph F.A., Li, Wei, Cui, Liangliang, Wei, Haiying, Pinkerton, Kent E.

“…[Display omitted] •Time-lagged effects were evaluated in mice following repeated exposures to one of three PM extract samples.•All three PM extracts induced…”
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Aryl Hydrocarbon Receptor Signaling Synergizes with TLR/NF-κB-Signaling for Induction of IL-22 Through Canonical and Non-Canonical AhR Pathways by Ishihara, Yasuhiro, Kado, Sarah Y, Bein, Keith J, He, Yi, Pouraryan, Arshia A, Urban, Angelika, Haarmann-Stemmann, Thomas, Sweeney, Colleen, Vogel, Christoph F A

“…Interleukin 22 (IL-22) is critically involved in gut immunity and host defense and primarily produced by activated T cells. In different circumstances IL-22…”
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Chronic exposure to traffic-related air pollution reduces lipid mediators of linoleic acid and soluble epoxide hydrolase in serum of female rats by Liang, Nuanyi, Emami, Shiva, Patten, Kelley T., Valenzuela, Anthony E., Wallis, Christopher D., Wexler, Anthony S., Bein, Keith J., Lein, Pamela J., Taha, Ameer Y.

“…Chronic exposure to traffic-related air pollution (TRAP) is known to promote systemic inflammation, which is thought to underlie respiratory, cardiovascular,…”
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