Search Results - "Beilles, Stéphane"

Application of Low-Frequency Raman Scattering Spectroscopy to Probe in Situ Drug Solubilization in Milk during Digestion by Salim, Malinda, Fraser-Miller, Sara J, Sutton, Joshua J, Be̅rziņš, Ka̅rlis, Hawley, Adrian, Clulow, Andrew J, Beilles, Stéphane, Gordon, Keith C, Boyd, Ben J

“…We have recently shown that real-time monitoring of drug solubilization and changes to solid state of the drug during digestion of milk can be achieved using…”
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Low-Frequency Raman Scattering Spectroscopy as an Accessible Approach to Understand Drug Solubilization in Milk-Based Formulations during Digestion by Salim, Malinda, Fraser-Miller, Sara J, Be̅rziņš, Ka̅rlis, Sutton, Joshua J, Ramirez, Gisela, Clulow, Andrew J, Hawley, Adrian, Beilles, Stéphane, Gordon, Keith C, Boyd, Ben J

“…Techniques enabling in situ monitoring of drug solubilization and changes in the solid-state of the drug during the digestion of milk and milk-based…”
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IMI – oral biopharmaceutics tools project – evaluation of bottom-up PBPK prediction success part 1: Characterisation of the OrBiTo database of compounds by Margolskee, Alison, Darwich, Adam S., Pepin, Xavier, Pathak, Shriram M., Bolger, Michael B., Aarons, Leon, Rostami-Hodjegan, Amin, Angstenberger, Jonas, Graf, Franziska, Laplanche, Loic, Müller, Thomas, Carlert, Sara, Daga, Pankaj, Murphy, Dónal, Tannergren, Christer, Yasin, Mohammed, Greschat-Schade, Susanne, Mück, Wolfgang, Muenster, Uwe, van der Mey, Dorina, Frank, Kerstin Julia, Lloyd, Richard, Adriaenssen, Lieve, Bevernage, Jan, De Zwart, Loeckie, Swerts, Dominique, Tistaert, Christophe, Van Den Bergh, An, Van Peer, Achiel, Beato, Stefania, Nguyen-Trung, Anh-Thu, Bennett, Joanne, McAllister, Mark, Wong, Mei, Zane, Patricia, Ollier, Céline, Vicat, Pascale, Kolhmann, Markus, Marker, Alexander, Brun, Priscilla, Mazuir, Florent, Beilles, Stéphane, Venczel, Marta, Boulenc, Xavier, Loos, Petra, Lennernäs, Hans, Abrahamsson, Bertil

“…Predicting oral bioavailability (Foral) is of importance for estimating systemic exposure of orally administered drugs. Physiologically-based pharmacokinetic…”
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Oscillating Crystallization in Solution between (+)- and (−)-5-Ethyl-5-methylhydantoin under the Influence of Stirring by Gervais, Claire, Beilles, Stéphane, Cardinaël, Pascal, Petit, Samuel, Coquerel, Gérard

“…Although the title compound crystallizes as a stable conglomerate without any detectable solid solution, particles in the shape of single crystals grown from…”
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Adding a Gastric Step to the Intestinal In Vitro Digestion Model Improves the Prediction of Pharmacokinetic Data in Beagle Dogs of Two Lipid-Based Drug Delivery Systems by Klitgaard, Mette, Beilles, Stephane, Sassene, Philip Jonas, Berthelsen, Ragna, Müllertz, Anette

“…Drug release from a lipid-based drug delivery system (LbDDS) is typically studied in vitro using a one-step intestinal digestion model. However, lately the…”
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Impact of Ferroquine on the Solubilization of Artefenomel (OZ439) during in Vitro Lipolysis in Milk and Implications for Oral Combination Therapy for Malaria by Salim, Malinda, Khan, Jamal, Ramirez, Gisela, Murshed, Mubtasim, Clulow, Andrew J, Hawley, Adrian, Ramachandruni, Hanu, Beilles, Stephane, Boyd, Ben J

“…Milk is an attractive lipid-based formulation for the delivery of poorly water-soluble drugs to pediatric populations. We recently observed that solubilization…”
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Lipid Compositions in Infant Formulas Affect the Solubilization of Antimalarial Drugs Artefenomel (OZ439) and Ferroquine during Digestion by Salim, Malinda, Ramirez, Gisela, Peng, Kang-Yu, Clulow, Andrew J, Hawley, Adrian, Ramachandruni, Hanu, Beilles, Stephane, Boyd, Ben J

“…Recent studies have shown that the solubilization of two antimalarial drug candidates, artefenomel (OZ439) and ferroquine (FQ), designed to provide a…”
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Preferential crystallisation and comparative crystal growth study between pure enantiomer and racemic mixture of a chiral molecule: 5-ethyl-5-methylhydantoin by Beilles, Stéphane, Cardinael, Pascal, Ndzié, Elias, Petit, Samuel, Coquerel, Gérard

“…It is shown that (±) 5-ethyl-5-methylhydantoin (12Hyd) can be separated at a preparative scale by means of the auto-seeded and polythermic preferential…”
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IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling strategies by Ahmad, Amais, Pepin, Xavier, Aarons, Leon, Wang, Yuya, Darwich, Adam S., Wood, J. Matthew, Tannergren, Christer, Karlsson, Eva, Patterson, Claire, Thörn, Helena, Ruston, Linette, Mattinson, Alex, Carlert, Sara, Berg, Staffan, Murphy, Donal, Engman, Helena, Laru, Johanna, Barker, Richard, Flanagan, Talia, Abrahamsson, Bertil, Budhdeo, Shanoo, Franek, Frans, Moir, Andrea, Hanisch, Gunilla, Pathak, Shriram M., Turner, David, Jamei, Masoud, Brown, Jonathan, Good, David, Vaidhyanathan, Shruthi, Jackson, Claire, Nicolas, Olivier, Beilles, Stephane, Nguefack, Jean-Flaubert, Louit, Guillaume, Henrion, Louis, Ollier, Celine, Boulu, Laurent, Xu, Christine, Heimbach, Tycho, Ren, Xiojun, Lin, Wen, Nguyen-Trung, Anh-Thu, Zhang, Jin, He, Handan, Wu, Fan, Bolger, Michael B., Mullin, James M., van Osdol, Bill, Szeto, Ke, Korjamo, Timo, Pappinen, Sari, Tuunainen, Johanna, Zhu, Wei, Xia, Binfeng, Daublain, Pierre, Wong, Suet, Varma, Manthena V.S., Modi, Sweta, Schäfer, Kerstin Julia, Schmid, Kartrin, Lloyd, Richard, Patel, Aarti, Tistaert, Christophe, Bevernage, Jan, Nguyen, Mai Anh, Lindley, David, Carr, Robert, Rostami-Hodjegan, Amin

“…[Display omitted] Oral drug absorption is a complex process depending on many factors, including the physicochemical properties of the drug, formulation…”
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