Search Results - "Beil, Winfried"
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Oral antidiabetic drug metabolism: pharmacogenomics and drug interactions
Published in Expert opinion on drug metabolism & toxicology (01-03-2009)“…Type 2 diabetes is progressive in nature and so to control cardiovascular risk, most patients need combinations of oral antidiabetic drugs (OADs) plus or minus…”
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Caboxamycin, a new antibiotic of the benzoxazole family produced by the deep-sea strain Streptomyces sp. NTK 937
Published in Journal of antibiotics (01-02-2009)“…Caboxamycin, a new benzoxazole antibiotic, was detected by HPLC-diode array screening in extracts of the marine strain Streptomyces sp. NTK 937, which was…”
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Proximicin A, B and C, Novel Aminofuran Antibiotic and Anticancer Compounds Isolated from Marine Strains of the Actinomycete Verrucosispora
Published in Journal of antibiotics (01-03-2008)“…A family of three novel aminofuran antibiotics named as proximicins was isolated from the marine Verrucosispora strain MG-37. Proximicin A was detected in…”
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4
Localization, Trafficking, and Significance for Acid Secretion of Parietal Cell Kir4.1 and KCNQ1 K+ Channels
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2008)“…Background & Aims: K+ recycling at the apical membrane of gastric parietal cells is a prerequisite for gastric acid secretion. Two K+ channels are currently…”
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Piceamycin and its N-acetylcysteine adduct is produced by Streptomyces sp. GB 4-2
Published in Journal of antibiotics (01-09-2009)“…Piceamycin, a new macrolactam polyketide antibiotic, was detected by HPLC-diode array screening in extracts of Streptomyces sp. GB 4-2, which was isolated from…”
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Nataxazole, a New Benzoxazole Derivative with Antitumor Activity Produced by Streptomyces sp. Tü 6176
Published in Journal of antibiotics (01-11-2008)“…The new benzoxazole derivative nataxazole was isolated from Streptomyces sp. (strain Tü 6176). Nataxazole is related in structure to the potent antitumor…”
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7
Severe hypoglycemia due to possible interaction between glibenclamide and sorafenib in a patient with hepatocellular carcinoma
Published in Current drug safety (01-04-2013)“…There is increasing evidence that tyrosine kinase inhibitors (TKIs) have significant blood glucose lowering effects. A 70-year old Caucasian male with liver…”
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Differential Effects of Multiplicity of Infection on Helicobacter pylori-Induced Signaling Pathways and Interleukin-8 Gene Transcription
Published in Journal of clinical immunology (01-02-2011)“…Interleukin-8 (IL-8) plays a central role in the pathogenesis of Helicobacter pylori infection. We used four different H. pylori strains isolated from patients…”
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New aminophenoxazinones from a marine Halomonas sp.: fermentation, structure elucidation, and biological activity
Published in Journal of antibiotics (01-02-2006)“…The addition of anthranilic acid to the culture medium of the marine derived Halomonas sp. strain GWS-BW-H8hM completely altered the secondary metabolite…”
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Pyrocoll, an antibiotic, antiparasitic and antitumor compound produced by a novel alkaliphilic Streptomyces strain
Published in Journal of antibiotics (01-07-2003)“…A new secondary metabolite was detected in the culture extract of Streptomyces sp. AK 409 by HPLC-diode-array screening. The metabolite was identified as…”
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Aranciamycin anhydride, a new anthracycline-type antibiotic isolated from Streptomyces sp. Tü 6384
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Nocardichelins A and B, Siderophores from Nocardia Strain Acta 3026
Published in Journal of natural products (Washington, D.C.) (01-06-2007)“…An actinomycete, strain Acta 3026, isolated from mangrove soil was characterized and found to belong to the genus Nocardia. The strain produces two new…”
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Two new bicyclic cembranolides from a new Sarcophyton species and determination of the absolute configuration of sarcoglaucol-16-one
Published in Organic & biomolecular chemistry (21-04-2004)“…During the chemical investigation of a new species of soft coral belonging to the genus Sarcophyton, two novel cembranoid compounds with a 12Z double bond (1…”
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Fluostatins C-E, novel members of the fluostatin family produced by Streptomyces strain Acta 1383
Published in Journal of antibiotics (01-05-2006)“…Three new members of the fluostatin family, fluostatins C-E, were discovered in a culture filtrate extract of strain Acta 1383 during an HPLC screening…”
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Stringent time-dependent transregulation of calcium calmodulin kinase II (CaMKII) is implicated in anti-apoptotic control
Published in Biochimica et biophysica acta (01-02-2008)“…Induction of apoptosis by the PP1/PP2A inhibitor calyculin A was inhibited if the CaMKII inhibitor KN-93 was added no later than 10 min after addition of…”
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Lactonamycin Z, an antibiotic and antitumor compound produced by Streptomyces sanglieri strain AK 623
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Elloxazinones A and B, New Aminophenoxazinones from Streptomyces griseus Acta 2871
Published in Journal of antibiotics (01-04-2007)“…Two new aminophenoxazinone compounds with antitumor activity, elloxazinone A and B, were isolated from the culture filtrate of Streptomyces griseus Acta 2871…”
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Retymicin, galtamycin B, saquayamycin Z and ribofuranosyllumichrome, novel secondary metabolites from Micromonospora sp. Tü 6368. I. Taxonomy, fermentation, isolation and biological activities
Published in Journal of antibiotics (01-02-2005)“…A new xanthone compound named retymicin (1) was isolated together with galtamycin B (2) and saquayamycin Z (3), new members of the galtamycin and saquayamycin…”
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Nataxazole, a New Benzoxazole Derivative with Antitumor Activity Produced by Streptomyces sp. Tue 6176
Published in Journal of antibiotics (25-11-2008)“…The new benzoxazole derivative nataxazole was isolated from Streptomyces sp. (strain Tue 6176). Nataxazole is related in structure to the potent antitumor…”
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New biologically active rubiginones from Streptomyces sp
Published in Journal of antibiotics (2000)“…Four new polyketides, named rubiginone D2 (2), 4-O-acetyl-rubiginone D2 (3), rubiginone H (6) and rubiginone I (7) were isolated from the cultures of…”
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