Search Results - "Beijer, B"

PAMAM Structure-Based Multifunctional Fluorescent Conjugates for Improved Fluorescent Labelling of Biomacromolecules by Wängler, C., Moldenhauer, G., Saffrich, R., Knapp, E.-M., Beijer, B., Schnölzer, M., Wängler, B., Eisenhut, M., Haberkorn, U., Mier, W.

“…Fluorescent probes are of increasing interest in medicinal and biological applications for the elucidation of the structures and functions of healthy as well…”
Get full text

Fast and simple purification of chemically modified hammerhead ribozymes using a lipophilic capture tag by Sproat, Brian S., Rupp, Thomas, Menhardt, Norbert, Keane, Doreen, Beijer, Barbro

“…A new type of 5′-lipophilic capture tag is described, enabling the facile reverse phase HPLC purification of chemically modified hammerhead ribozymes…”
Get full text

Influence of transfer RNA tertiary structure on aminoacylation efficiency by glutaminyl and cysteinyl-tRNA synthetases by Sherlin, L D, Bullock, T L, Newberry, K J, Lipman, R S, Hou, Y M, Beijer, B, Sproat, B S, Perona, J J

“…The position of the tertiary Levitt pair between nucleotides 15 and 48 in the transfer RNA core region suggests a key role in stabilizing the joining of the…”
Get full text

Pharmacokinetics of a synthetic, chemically modified hammerhead ribozyme against the rat cytochrome P-450 3A2 mRNA after single intravenous injections by Desjardins, J P, Sproat, B S, Beijer, B, Blaschke, M, Dunkel, M, Gerdes, W, Ludwig, J, Reither, V, Rupp, T, Iversen, P L

“…Modulation of gene expression via nucleic acid sequence-specific intervention represents a new paradigm for drug discovery and development. Ribozymes are small…”
Get more information

Identification of four borrelia burgdorferi sensu lato species in ixodes ricinus ticks collected from dutch dogs by Hovius, K.E., Beijer, B., Rijpkema, S.G.I, Bleumink-Pluym, N.M.C., Houwers, D. J.

“…The prevalence of Borrelia species infection was determined by polymerase chain reaction (PCR) in 138 ticks collected from dogs which were walked regularly in…”
Get full text

Cover Picture: PAMAM Structure-Based Multifunctional Fluorescent Conjugates for Improved Fluorescent Labelling of Biomacromolecules (Chem. Eur. J. 27/2008) by Wängler, C., Moldenhauer, G., Saffrich, R., Knapp, E.-M., Beijer, B., Schnölzer, M., Wängler, B., Eisenhut, M., Haberkorn, U., Mier, W.

Get full text

How glutaminyl-tRNA synthetase selects glutamine by Rath, Virginia L, Silvian, Laura F, Beijer, Barbro, Sproat, Brian S, Steitz, Thomas A

“…Background: Aminoacyl-tRNA synthetases covalently link a specific amino acid to the correct tRNA. The fidelity of this reaction is essential for accurate…”
Get full text

2'-O-alkyloligoribonucleotides, synthesis and applications in molecular biology by Sproat, B S, Lamond, A I, Garcia, R G, Beijer, B, Pieles, U, Douglas, M, Bohmann, K, Carmo-Fonseco, M, Weston, S, O'Loughlin, S

“…Oligo(2'-O-alkylribonucleotides) have been synthesized in which alkyl is methyl, allyl and butyl. The various phosphoramidite monomers of 2'-O-alkyl uridine,…”
Get more information

Crystal Structures at 2.5 Angstrom Resolution of Seryl-tRNA Synthetase Complexed with Two Analogs of Seryl Adenylate by Belrhali, Hassan, Yaremchuk, Anna, Tukalo, Michael, Larsen, Kjeld, Berthet-Colominas, Carmen, Leberman, Reuben, Beijer, Barbro, Sproat, Brian, Als-Nielsen, Jens, Grübel, Gerhard, Legrand, Jean-François, Lehmann, Mogens, Cusack, Stephen

“…Crystal structures of seryl-tRNA synthetase from Thermus thermophilus complexed with two different analogs of seryl adenylate have been determined at 2.5 Å…”
Get full text

Fluorescent somatostatin receptor probes for the intraoperative detection of tumor tissue with long-wavelength visible light by MIER, Walter, BEIJER, Barbro, GRAHAM, Keith, HULL, William E

“…Targeted fluorescent dyes are of substantial value for the intraoperative delineation of primary tumors and metastatic lesions. For this purpose…”
Get full text

Highly efficient chemical synthesis of 2'-O-methyloligoribonucleotides and tetrabiotinylated derivatives; novel probes that are resistant to degradation by RNA or DNA specific nucleases by Sproat, B S, Lamond, A I, Beijer, B, Neuner, P, Ryder, U

“…2'-O-Methyloligoribonucleotides have been synthesised on solid phase from base protected 5'-O-dimethoxytrityl-2'-O-methylribonucleoside-3'-O-(2-cyanoethyl…”
Get full text

2′- O-(carbamoylmethyl)oligoribonucleotides by Grøtli, Morten, Beijer, Barbro, Sproat, Brian

“…Fully modified oligonucleotides containing 2′- O-cyanomethylribonucleotides were synthesised on automated DNA synthesisers using protected 2′-…”
Get full text

A simple method for the synthesis of 2′- O-alkylguanosine derivatives by Grøtli, Morten, Douglas, Mark, Beijer, Barbro, Eritja, Ramon, Sproat, Brian

“…A new synthetic route has been devised for the preparation of 2′- O-alkyl guanosine derivatives. Utilizing a strategy of minimal protection, the alkylation was…”
Get full text

A simple method for the synthesis of 2'-0-alkylguanosine derivatives by GRØTLI, M, DOUGLAS, M, BEIJER, B, ERITJA, R, SPROAT, B

Get full text

New synthetic routes to protected purine 2'-O-methylriboside-3'-O-phosphoramidites using a novel alkylation procedure by SPROAT, B. S, BEIEJER, B, IRIBARREN, A

“…A highly selective alkylation procedure has been developed enabling new synthetic routes to be established for protected purine…”
Get full text

The synthesis of protected 5'-mercapto-2',5'-dideoxyribonucleoside-3'-O-phosphoramidites; uses of 5'-mercapto-oligodeoxyribonucleotides by SPROAT, B. S, BEIJER, B, RIDER, P, NEUNER, P

“…The syntheses of the four novel, base protected 5'-(S-triphenylmethyl)mercapto-2',5'-dideoxyribonucleoside-3 '-O-(2-cyanoethyl N,N-diisopropylphosphoramidites)…”
Get full text

Synthesis and applications of oligoribonucleotides with selected 2'-O-methylation using the 2'-O-[1-(2-fluorophenyl)-4-methoxypiperidin-4-yl] protecting group by Beijer, B, Sulston, I, Sproat, B S, Rider, P, Lamond, A I, Neuner, P

“…The synthesis of base protected 5'-O-dimethoxytrityl-2'-O-[1-(2- fluorophenyl)-4-methoxypiperidin-4-yl]-3'-O-(2-cyanoethyl N,N-diisopropylphosphoramidites) is…”
Get full text

New synthetic routes to synthons suitable for 2'-O-allyloligoribonucleotide assembly by Sproat, B S, Iribarren, A M, Garcia, R G, Beijer, B

“…New synthetic routes have been devised for the high yield preparation of protected 2'-O-allylribonucleoside-3'-O-phosphoramidites, exemplified by the…”
Get full text

New synthetic routes to synthons suitable for 2'-O-allyloliforibunucleotide assembly by SPROAT, B. S, IRIBARREN, A. M, GUIMIL GARCIA, R, BEIJER, B

Get full text

The synthesis of protected 5'-amino-2',5'-dideoxyribonucleoside-3'-O-phosphoramidites; applications of 5'-amino-oligodeoxyribonucleotides by SPROAT, B. S, BEIJER, B, RIDER, P

“…Synthetic routes to the four appropriately protected 5'-amino-2',5'-dideoxyribonucleoside-3'-O-(2-cyanoethyl N,N-diisopropylphosphoramidites) have been…”
Get full text