Search Results - "Beigelman, Leonid N"

Regulation of gene transcription by thyroid hormone receptor β agonists in clinical development for the treatment of non-alcoholic steatohepatitis (NASH) by Luong, Xuan G, Stevens, Sarah K, Jekle, Andreas, Lin, Tse-I, Gupta, Kusum, Misner, Dinah, Chanda, Sushmita, Mukherjee, Sucheta, Williams, Caroline, Stoycheva, Antitsa, Blatt, Lawrence M, Beigelman, Leonid N, Symons, Julian A, Raboisson, Pierre, McGowan, David, Vandyck, Koen, Deval, Jerome

“…Thyroid hormones are important modulators of metabolic activity in mammals and alter cholesterol and fatty acid levels through activation of the nuclear…”
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Discovery and Preclinical Profile of ALG-055009, a Potent and Selective Thyroid Hormone Receptor Beta (THR-β) Agonist for the Treatment of MASH by Vandyck, Koen, McGowan, David C, Luong, Xuan G, Stevens, Sarah K, Jekle, Andreas, Gupta, Kusum, Misner, Dinah L, Chanda, Sushmita, Serebryany, Vladimir, Welch, Michael, Hu, Haiyang, Lv, Zhidan, Williams, Caroline, Maskos, Klaus, Lammens, Alfred, Stoycheva, Antitsa D, Lin, Tse-I, Blatt, Lawrence M, Beigelman, Leonid N, Symons, Julian A, Raboisson, Pierre, Deval, Jerome

“…Agonists of thyroid hormone receptor β (THR-β) decreased LDL cholesterol (LDL-C) and triglyceride (TG) levels in human clinical trials for patients with…”
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Development of a Hyperglycosylated IFN Alfacon-1 (CIFN): Toward Bimonthly or Monthly Dosing for Antiviral Therapies by Taylor, Joshua S, Zhang, Qingling, Julander, Justin G, Stoycheva, Antitsa D, Tan, Hua, Moy, Christabel V, Chanda, Sushmita, Symons, Julian A, Beigelman, Leonid N, Blatt, Lawrence M, Hong, Jin

“…Type 1 interferons (IFNs) have been shown to be efficacious against hepatitis C virus (HCV), hepatitis B virus (HBV), and some cancers with a significant…”
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Regulation of gene transcription by thyroid hormone receptor [beta] agonists in clinical development for the treatment of non-alcoholic steatohepatitis by Luong, Xuan G, Stevens, Sarah K, Jekle, Andreas, Lin, Tse-I, Gupta, Kusum, Misner, Dinah, Chanda, Sushmita, Mukherjee, Sucheta, Williams, Caroline, Stoycheva, Antitsa, Blatt, Lawrence M, Beigelman, Leonid N, Symons, Julian A, Raboisson, Pierre, McGowan, David, Vandyck, Koen, Deval, Jerome

“…Thyroid hormones are important modulators of metabolic activity in mammals and alter cholesterol and fatty acid levels through activation of the nuclear…”
Get full text