Search Results - "Beierle, John M."

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  1. 1

    Temperature-Responsive "Catch and Release" of Proteins by using Multifunctional Polymer-Based Nanoparticles by Yoshimatsu, Keiichi, Lesel, Benjamin K., Yonamine, Yusuke, Beierle, John M., Hoshino, Yu, Shea, Kenneth J.

    Published in Angewandte Chemie International Edition (05-03-2012)
    “…Catch me if you can: Multifunctional, polymer‐based nanoparticles that are capable of temperature‐responsive “catch‐and‐release” of a target protein have been…”
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    Journal Article
  2. 2

    Autoamplification of Molecular Chirality through the Induction of Supramolecular Chirality by van Dijken, Derk Jan, Beierle, John M., Stuart, Marc C. A., Szymański, Wiktor, Browne, Wesley R., Feringa, Ben L.

    Published in Angewandte Chemie International Edition (12-05-2014)
    “…The novel concept for the autoamplification of molecular chirality, wherein the amplification proceeds through the induction of supramolecular chirality, is…”
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    Journal Article
  3. 3

    Probing the Bioactive Conformation of an Archetypal Natural Product HDAC Inhibitor with Conformationally Homogeneous Triazole-Modified Cyclic Tetrapeptides by Horne, W. Seth, Olsen, Christian A, Beierle, John M, Montero, Ana, Ghadiri, M. Reza

    Published in Angewandte Chemie (International ed.) (01-01-2009)
    “…Fooling enzymes with mock amides: Analogues of apicidin, a cyclic-tetrapeptide inhibitor of histone deacetylase (HDAC), were designed with a 1,4- or…”
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    Self-Assembling Sequence-Adaptive Peptide Nucleic Acids by Ura, Yasuyuki, Beierle, John M, Leman, Luke J, Orgel, Leslie E, Ghadiri, M. Reza

    “…Several classes of nucleic acid analogs have been reported, but no synthetic informational polymer has yet proven responsive to selection pressures under…”
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    Light–induced disassembly of self-assembled vesicle-capped nanotubes observed in real time by Coleman, Anthony C., Beierle, John M., Stuart, Marc C. A., Maciá, Beatriz, Caroli, Giuseppe, Mika, Jacek T., van Dijken, Derk Jan, Chen, Jiawen, Browne, Wesley R., Feringa, Ben L.

    Published in Nature nanotechnology (14-08-2011)
    “…Molecular self-assembly is the basis for the formation of numerous artificial nanostructures 1 , 2 . The self-organization of peptides 3 , 4 , 5 , 6 ,…”
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    Epitope Discovery for a Synthetic Polymer Nanoparticle: A New Strategy for Developing a Peptide Tag by Yoshimatsu, Keiichi, Yamazaki, Tomohiko, Hoshino, Yu, Rose, Paul E, Epstein, Linda F, Miranda, Les P, Tagari, Philip, Beierle, John M, Yonamine, Yusuke, Shea, Kenneth J

    Published in Journal of the American Chemical Society (29-01-2014)
    “…We describe a novel epitope discovery strategy for creating an affinity agent/peptide tag pair. A synthetic polymer nanoparticle (NP) was used as the “bait” to…”
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    Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches by Szymański, Wiktor, Beierle, John M, Kistemaker, Hans A. V, Velema, Willem A, Feringa, Ben L

    Published in Chemical reviews (14-08-2013)
    “…Issues surrounding the reversible photocontrol of biological systems by the incorporation of molecular photoswitches are examined. Photoswitches are used for…”
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  9. 9

    Dynamic polythioesters via ring-opening polymerization of 1,4-thiazine-2,5-diones by Ura, Yasuyuki, Al-Sayah, Mohammad, Montenegro, Javier, Beierle, John M, Leman, Luke J, Ghadiri, M Reza

    Published in Organic & biomolecular chemistry (01-01-2009)
    “…We describe the preparation and characterization of polythioesters composed of alternating alpha-amino acid and alpha-thioglycolic acid residues that undergo…”
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    A Fast-Moving [2]Rotaxane Whose Stoppers Are Remote from the Copper Complex Core by Létinois-Halbes, Ulla, Hanss, David, Beierle, John M, Collin, Jean-Paul, Sauvage, Jean-Pierre

    Published in Organic letters (22-12-2005)
    “…A new copper-complexed rotaxane is described. It consists of a two-coordination site ring threaded by a sterically non-hindering 2,2‘-bipyridine derivative. An…”
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    Templated Self-Assembly of Dynamic Peptide Nucleic Acids by Beierle, John M, Ura, Yasuyuki, Ghadiri, M. Reza, Leman, Luke J

    Published in Biochemistry (Easton) (09-01-2018)
    “…Template-directed macromolecule synthesis is a hallmark of living systems. Inspired by this natural process, several fundamentally novel mechanisms for…”
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  12. 12

    Polymer Nanoparticle Hydrogels with Autonomous Affinity Switching for the Protection of Proteins from Thermal Stress by Beierle, John M., Yoshimatsu, Keiichi, Chou, Beverly, Mathews, Michael A. A., Lesel, Benjamin K., Shea, Kenneth J.

    Published in Angewandte Chemie International Edition (25-08-2014)
    “…We report a new material design concept for synthetic, thermally responsive poly(N‐isopropylacrylamide)‐based copolymer nanoparticle (NP) hydrogels, which…”
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  13. 13

    Metal-Free Polymer-Based Affinity Medium for Selective Purification of His6-Tagged Proteins by Yoshimatsu, Keiichi, Fruehauf, Krista R, Zhu, Quanhong, Weisman, Adam, Fan, Jun, Xue, Min, Beierle, John M, Rose, Paul E, Aral, Jennifer, Epstein, Linda F, Tagari, Philip, Miranda, Les P, Shea, Kenneth J

    Published in Biomacromolecules (12-04-2021)
    “…We report a metal free synthetic hydrogel copolymer with affinity and selectivity for His6-tagged peptides and proteins. Small libraries of copolymers…”
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  14. 14

    Design, Synthesis, Biological Evaluation, and Structural Characterization of Potent Histone Deacetylase Inhibitors Based on Cyclic α/β-Tetrapeptide Architectures by Montero, Ana, Beierle, John M, Olsen, Christian A, Ghadiri, M. Reza

    Published in Journal of the American Chemical Society (04-03-2009)
    “…Histone deacetylases (HDACs) are a family of enzymes found in bacteria, fungi, plants, and animals that profoundly affect cellular function by catalyzing the…”
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  15. 15

    Autoamplification of Molecular Chirality through the Induction of Supramolecular Chirality by van Dijken, Derk Jan, Beierle, John M., Stuart, Marc C. A., Szymański, Wiktor, Browne, Wesley R., Feringa, Ben L.

    Published in Angewandte Chemie (12-05-2014)
    “…The novel concept for the autoamplification of molecular chirality, wherein the amplification proceeds through the induction of supramolecular chirality, is…”
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    Journal Article
  16. 16

    An Improved Method for Site-Specific End Modification of Zeolite L for the Formation of Zeolite L and Gold Nanoparticle Self-Assembled Structures by Beierle, John M., Roswanda, Robby, Erne, Petra M., Coleman, Anthony C., Browne, Wesley R., Feringa, Ben L.

    “…The ability to site‐selectively modify micro‐ and nanosized particles has allowed for directed self‐assembly in two and three dimensions. Site‐selective…”
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  17. 17

    Polymer Nanoparticle Hydrogels with Autonomous Affinity Switching for the Protection of Proteins from Thermal Stress by Beierle, John M., Yoshimatsu, Keiichi, Chou, Beverly, Mathews, Michael A. A., Lesel, Benjamin K., Shea, Kenneth J.

    Published in Angewandte Chemie (25-08-2014)
    “…We report a new material design concept for synthetic, thermally responsive poly(N‐isopropylacrylamide)‐based copolymer nanoparticle (NP) hydrogels, which…”
    Get full text
    Journal Article
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    Temperature-Responsive "Catch and Release" of Proteins by using Multifunctional Polymer-Based Nanoparticles by Yoshimatsu, Keiichi, Lesel, Benjamin K., Yonamine, Yusuke, Beierle, John M., Hoshino, Yu, Shea, Kenneth J.

    Published in Angewandte Chemie (05-03-2012)
    “…Fang mich doch! Multifunktionelle polymerbasierte Nanopartikel wurden synthetisiert, die Zielproteine reversibel und temperaturgesteuert einfangen und wieder…”
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    Synthesis of Louisianin C by Beierle, John M, Osimboni, Ekundayo B, Metallinos, Costa, Zhao, Yajun, Kelly, T. Ross

    Published in Journal of organic chemistry (13-06-2003)
    “…The synthesis of louisianin C (3), a member of a small family of 3,4,5-trisubstituted pyridyl natural products, is achieved in six steps and 11% overall yield…”
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