Search Results - "Beierle, Jacob A."

Exercise-Associated Changes in the Corticosterone Response to Acute Restraint Stress: Evidence for Increased Adrenal Sensitivity and Reduced Corticosterone Response Duration by HARE, Brendan D, BEIERLE, Jacob A, TOUFEXIS, Donna J, HAMMACK, Sayamwong E, FALLS, William A

“…Exercise promotes stress resistance and is associated with reduced anxiety and reduced depression in both humans and in animal models. Despite the fact that…”
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The effect of the demyelinating agent cuprizone on binge-like eating of sweetened palatable food in female and male C57BL/6 substrains by Babbs, Richard K., Beierle, Jacob A., Yao, Emily J., Kelliher, Julia C., Medeiros, Arthurine R., Anandakumar, Jeya, Shah, Anyaa A., Chen, Melanie M., Johnson, William E., Bryant, Camron D.

“…Binge eating is a heritable symptom of eating disorders with an unknown genetic etiology. Rodent models for binge-like eating (BLE) of palatable food permit…”
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Assessment of Binge-Like Eating of Unsweetened vs. Sweetened Chow Pellets in BALB/c Substrains by Sena, Katherine D, Beierle, Jacob A, Richardson, Kayla T, Kantak, Kathleen M, Bryant, Camron D

“…Binge eating disorder (BED) is defined as chronic episodes of consuming large amounts of food in less than 2 h. Binge eating disorder poses a serious public…”
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Effect of Prenatal Opioid Exposure on the Human Placental Methylome by Borrelli, Kristyn N, Wachman, Elisha M, Beierle, Jacob A, Taglauer, Elizabeth S, Jain, Mayuri, Bryant, Camron D, Zhang, Huiping

“…Prenatal exposure to addictive drugs can lead to placental epigenetic modifications, but a methylome-wide evaluation of placental DNA methylation changes after…”
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Cyfip1 Haploinsufficiency Increases Compulsive-Like Behavior and Modulates Palatable Food Intake in Mice: Dependence on Cyfip2 Genetic Background, Parent-of Origin, and Sex by Babbs, Richard K, Beierle, Jacob A, Ruan, Qiu T, Kelliher, Julia C, Chen, Melanie M, Feng, Ashley X, Kirkpatrick, Stacey L, Benitez, Fabiola A, Rodriguez, Fred A, Pierre, Johanne J, Anandakumar, Jeya, Kumar, Vivek, Mulligan, Megan K, Bryant, Camron D

“…Binge eating (BE) is a heritable trait associated with eating disorders and involves episodes of rapid, large amounts of food consumption. We previously…”
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Placental OPRM1 DNA methylation and associations with neonatal opioid withdrawal syndrome, a pilot study by Wachman, Elisha M, Wang, Alice, Isley, Breanna C, Boateng, Jeffery, Beierle, Jacob A, Hansbury, Aaron, Shrestha, Hira, Bryant, Camron, Zhang, Huiping

“…Epigenetic variation of DNA methylation of the mu-opioid receptor gene ( ) has been identified in the blood and saliva of individuals with opioid use disorder…”
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Decreased myelin-related gene expression in the nucleus accumbens during spontaneous neonatal opioid withdrawal in the absence of long-term behavioral effects in adult outbred CFW mice by Borrelli, Kristyn N., Wingfield, Kelly K., Yao, Emily J., Zamorano, Catalina A., Sena, Katherine D., Beierle, Jacob A., Roos, Michelle A., Zhang, Huiping, Wachman, Elisha M., Bryant, Camron D.

“…Prenatal opioid exposure is a major health concern in the United States, with the incidence of neonatal opioid withdrawal syndrome (NOWS) escalating in recent…”
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The ultrasonic vocalization (USV) syllable profile during neonatal opioid withdrawal and a kappa opioid receptor component to increased USV emissions in female mice by Wingfield, Kelly K, Misic, Teodora, Jain, Kaahini, McDermott, Carly S, Abney, Nalia M, Richardson, Kayla T, Rubman, Mia B, Beierle, Jacob A, Miracle, Sophia A, Sandago, Emma J, Baskin, Britahny M, Lynch, William B, Borrelli, Kristyn N, Yao, Emily J, Wachman, Elisha M, Bryant, Camron D

“…Opioid use during pregnancy can lead to negative infant health outcomes, including neonatal opioid withdrawal syndrome (NOWS). NOWS comprises gastrointestinal,…”
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A Mutation in Hnrnph1 That Decreases Methamphetamine-Induced Reinforcement, Reward, and Dopamine Release and Increases Synaptosomal hnRNP H and Mitochondrial Proteins by Ruan, Qiu T, Yazdani, Neema, Blum, Benjamin C, Beierle, Jacob A, Lin, Weiwei, Coelho, Michal A, Fultz, Elissa K, Healy, Aidan F, Shahin, John R, Kandola, Amarpreet K, Luttik, Kimberly P, Zheng, Karen, Smith, Nathaniel J, Cheung, Justin, Mortazavi, Farzad, Apicco, Daniel J, Ragu Varman, Durairaj, Ramamoorthy, Sammanda, Ash, Peter E A, Rosene, Douglas L, Emili, Andrew, Wolozin, Benjamin, Szumlinski, Karen K, Bryant, Camron D

“…Individual variation in the addiction liability of amphetamines has a heritable genetic component. We previously identified (heterogeneous nuclear…”
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A reduced complexity cross between BALB/c substrains identifies Zhx2 as a candidate gene underlying oxycodone metabolite brain concentration and state‐dependent learning of opioid reward by Beierle, Jacob A., Yao, Emily J., Goldstein, Stan I., Scotellaro, Julia L., Sena, Katherine D., Averin, Olga, Moody, David E., Reilly, Christopher A., Emili, Andrew, Peltz, Gary, Ferris, Martin T., Bryant, Camron D.

“…Understanding the pharmacokinetic profile of an opioid drug is vital to therapeutic success, and mutations in human PK genes can drastically alter therapeutic…”
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5′ UTR variants in the quantitative trait gene Hnrnph1 support reduced 5′ UTR usage and hnRNP H protein as a molecular mechanism underlying reduced methamphetamine sensitivity by Ruan, Qiu T., Yazdani, Neema, Reed, Eric R., Beierle, Jacob A., Peterson, Lucy P., Luttik, Kimberly P., Szumlinski, Karen K., Johnson, William E., Ash, Peter E.A., Wolozin, Benjamin, Bryant, Camron D.

“…We previously identified a 210 kb region on chromosome 11 (50.37‐50.58 Mb, mm10) containing two protein‐coding genes (Hnrnph1, Rufy1) that was necessary for…”
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Zhx2 Is a Candidate Gene Underlying Oxymorphone Metabolite Brain Concentration Associated with State-Dependent Oxycodone Reward by Beierle, Jacob A, Yao, Emily J, Goldstein, Stanley I, Lynch, William B, Scotellaro, Julia L, Shah, Anyaa A, Sena, Katherine D, Wong, Alyssa L, Linnertz, Colton L, Averin, Olga, Moody, David E, Reilly, Christopher A, Peltz, Gary, Emili, Andrew, Ferris, Martin T, Bryant, Camron D

“…Understanding the pharmacogenomics of opioid metabolism and behavior is vital to therapeutic success, as mutations can dramatically alter therapeutic efficacy…”
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A quantitative trait variant in Gabra2 underlies increased methamphetamine stimulant sensitivity by Goldberg, Lisa R., Yao, Emily J., Kelliher, Julia C., Reed, Eric R., Wu Cox, Jiayi, Parks, Cory, Kirkpatrick, Stacey L., Beierle, Jacob A., Chen, Melanie M., Johnson, William E., Homanics, Gregg E., Williams, Robert W., Bryant, Camron D., Mulligan, Megan K.

“…Psychostimulant (methamphetamine, cocaine) use disorders have a genetic component that remains mostly unknown. We conducted genome‐wide quantitative trait…”
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Genetic basis of thermal nociceptive sensitivity and brain weight in a BALB/c reduced complexity cross by Beierle, Jacob A, Yao, Emily J, Goldstein, Stanley I, Scotellaro, Julia L, Sena, Katherine D, Linnertz, Colton A, Willits, Adam B, Kader, Leena, Young, Erin E, Peltz, Gary, Emili, Andrew, Ferris, Martin T, Bryant, Camron D

“…Thermal nociception involves the transmission of temperature-related noxious information from the periphery to the CNS and is a heritable trait that could…”
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Changes in neuronal immunofluorescence in the C- versus N-terminal domains of hnRNP H following D1 dopamine receptor activation by Ruan, Qiu T., Yazdani, Neema, Beierle, Jacob A., Hixson, Kathryn M., Hokenson, Kristen E., Apicco, Daniel J., Luttik, Kimberly P., Zheng, Karen, Maziuk, Brandon F., Ash, Peter E.A., Szumlinski, Karen K., Russek, Shelley J., Wolozin, Benjamin, Bryant, Camron D.

“…•We examined immunofluorescence and localization of hnRNP H following dopamine receptor activation in primary rat cortical neurons.•Activation of D1 dopamine…”
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