Search Results - "Beierle, Andee"
-
1
Wireless position sensing and normalization of embedded resonant sensors using a resonator array
Published in Sensors and actuators. A. Physical. (01-03-2020)“…[Display omitted] [Display omitted] •An array of four resonators is sufficient to wirelessly determine X, Y, and angular position of a portable…”
Get full text
Journal Article -
2
PP2A activation overcomes leptomeningeal dissemination in group 3 medulloblastoma
Published in The Journal of biological chemistry (01-11-2024)“…Leptomeningeal dissemination (LMD) is the primary cause of treatment failure in children with group 3 medulloblastoma (MB). Building on our previous work on…”
Get full text
Journal Article -
3
Artificial Tumor Microenvironments in Neuroblastoma
Published in Cancers (01-04-2021)“…In the quest to advance neuroblastoma therapeutics, there is a need to have a deeper understanding of the tumor microenvironment (TME). From extracellular…”
Get full text
Journal Article -
4
Altering fractionation during radiation overcomes radio-resistance in patient-derived glioblastoma cells assessed using a novel longitudinal radiation cytotoxicity assay
Published in Radiotherapy and oncology (21-11-2024)“…Current radiotherapy (RT) in glioblastoma (GBM) is delivered as constant dose fractions (CDF), which do not account for intratumoral-heterogeneity and…”
Get full text
Journal Article -
5
CDK4/6 Inhibition With Lerociclib is a Potential Therapeutic Strategy for the Treatment of Pediatric Sarcomas
Published in Journal of pediatric surgery (01-03-2024)“…Sarcomas are a heterogenous collection of bone and soft tissue tumors. The heterogeneity of these tumors makes it difficult to standardize treatment. CDK 4/6…”
Get full text
Journal Article -
6
Pre-Clinical Study Evaluating Novel Protein Phosphatase 2A Activators as Therapeutics for Neuroblastoma
Published in Cancers (13-04-2022)“…Protein phosphatase 2A (PP2A) functions as an inhibitor of cancer cell proliferation, and its tumor suppressor function is attenuated in many cancers. Previous…”
Get full text
Journal Article -
7
Preclinical evidence for employing MEK inhibition in NRAS mutated pediatric gastroenteropancreatic neuroendocrine-like tumors
Published in Translational oncology (01-09-2024)“…•Targetable NRAS mutation were identified in pediatric neuroendocrine-like tumors.•Primary and metastatic PDX cells harbor phenotypic and genetic…”
Get full text
Journal Article -
8
Metastatic human hepatoblastoma cells exhibit enhanced tumorigenicity, invasiveness and a stem cell-like phenotype
Published in Journal of pediatric surgery (01-06-2022)“…Metastatic hepatoblastoma continues to pose a significant treatment challenge, primarily because the precise mechanisms involved in metastasis are not fully…”
Get full text
Journal Article -
9
PIM3 kinase promotes tumor metastasis in hepatoblastoma by upregulating cell surface expression of chemokine receptor cxcr4
Published in Clinical & experimental metastasis (01-12-2022)“…Patients presenting with metastatic hepatoblastoma have limited treatment options and survival rates as low as 25%. We previously demonstrated that Proviral…”
Get full text
Journal Article -
10
Monitoring Wound Health through Bandages with Passive LC Resonant Sensors
Published in ACS sensors (22-01-2021)“…This paper details a passive, inductor–capacitor (LC) resonant sensor embedded in a commercial dressing for low-cost, contact-free monitoring of a wound; this…”
Get full text
Journal Article -
11
Downregulation of PDGFRß Signaling Overcomes Crizotinib Resistance in a TYRO3 and ALK Mutated Neuroendocrine-Like Tumor
Published in Translational oncology (01-07-2021)“…•Rare, high grade neuroendocrine-like pediatric tumor has TYRO3 and ALK mutations.•Crizotinib downregulates STAT3 and ERK1/2 signaling in tumor.•In vivo…”
Get full text
Journal Article -
12
Resonant Sensors for Low-Cost, Contact-Free Measurement of Hydrolytic Enzyme Activity in Closed Systems
Published in ACS sensors (24-08-2018)“…A passive, resonant sensor was developed that can be embedded in closed systems for wireless monitoring of hydrolytic enzyme activity. The resonators are…”
Get full text
Journal Article -
13
Targeting High-Risk Neuroblastoma Patient-Derived Xenografts with Oncolytic Virotherapy
Published in Cancers (01-02-2022)“…Cancer is the leading cause of death by disease in children, and over 15% of pediatric cancer-related mortalities are due to neuroblastoma. Current treatment…”
Get full text
Journal Article -
14
Using 3D-bioprinted models to study pediatric neural crest-derived tumors
Published in International journal of bioprinting (01-01-2023)“…The use of three-dimensional (3D) bioprinting has remained at the forefront of tissue engineering and has recently been employed for generating bioprinted…”
Get full text
Journal Article -
15
Rapid Characterization of Solid Tumors Using Resonant Sensors
Published in ACS omega (13-09-2022)“…Cancer continues to be a significant cause of non-traumatic pediatric mortality. Diagnosis of pediatric solid tumors is paramount to prescribing the correct…”
Get full text
Journal Article -
16
Physically Inspired Circuit Model for Systematic Analysis of Resonant Ion Sensor
Published in 2020 IEEE International Symposium on Circuits and Systems (ISCAS) (01-10-2020)“…Ions play a significant role in biological, industrial, and agricultural processes. Noninvasive, real-time detection of their presence and concentration has…”
Get full text
Conference Proceeding -
17
MODL-30. UTILIZING SERUM-FREE CO-CULTURE MODELS FOR IN-VITRO MODELING OF TUMOR-ASSOCIATED MACROPHAGES IN GLIOBLASTOMA
Published in Neuro-oncology (Charlottesville, Va.) (10-11-2023)Get full text
Journal Article -
18
Novel Technique for Preclinical Evaluation of Pediatric Sarcoma Therapeutics
Published in Journal of the American College of Surgeons (01-11-2022)Get full text
Journal Article -
19
TMOD-21. A NOVEL IN-VITRO METHOD TO MODEL MACROPHAGES IN GLIOBLASTOMA
Published in Neuro-oncology (Charlottesville, Va.) (12-11-2021)Get full text
Journal Article -
20
Establishing a Novel 3-Dimensional Printing Model to Study Pediatric Solid Tumors
Published in Journal of the American College of Surgeons (01-11-2021)Get full text
Journal Article