Search Results - "Beier, K."
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Impact of Androgen Receptor Activity on Prostate-Specific Membrane Antigen Expression in Prostate Cancer Cells
Published in International journal of molecular sciences (18-01-2022)“…Prostate-specific membrane antigen (PSMA) is an essential molecular regulator of prostate cancer (PCa) progression coded by the gene. The PSMA protein has…”
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Prostate Cancer's Silent Partners: Fibroblasts and Their Influence on Glutamine Metabolism Manipulation
Published in International journal of molecular sciences (01-09-2024)“…Cancer-associated fibroblast (CAF)s in the tumour microenvironment (TME) modulate the extracellular matrix, interact with cancer cells, and facilitate…”
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The Androgen Hormone-Induced Increase in Androgen Receptor Protein Expression Is Caused by the Autoinduction of the Androgen Receptor Translational Activity
Published in Current issues in molecular biology (25-01-2022)“…The androgen receptor (AR) plays a central role in prostate, muscle, bone and adipose tissue. Moreover, dysregulated AR activity is a driving force in prostate…”
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ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28
Published in Nature (London) (21-01-1999)“…The T-cell-specific cell-surface receptors CD28 and CTLA-4 are important regulators of the immune system. CD28 potently enhances those T-cell functions that…”
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5
HITEMP derived spectral database for the prediction of jet engine exhaust infrared emission using a statistical band model
Published in Journal of quantitative spectroscopy & radiative transfer (01-08-2012)“…The spectroscopic database HITEMP 2010 is used to upgrade the parameters of the statistical molecular band model which is part of the infrared signature…”
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A Systematic Comparison of Antiandrogens Identifies Androgen Receptor Protein Stability as an Indicator for Treatment Response
Published in Life (Basel, Switzerland) (25-08-2021)“…Antiandrogen therapy is a primary treatment for patients with metastasized prostate cancer. Whilst the biologic mechanisms of antiandrogens have been…”
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An Exploratory Study on the Central Nervous Correlates of Sexual Excitation and Sexual Inhibition
Published in The Journal of sex research (23-03-2020)“…The Sexual Inhibition/Sexual Excitation Scales (SIS/SES) measure sexual excitation and sexual inhibition proneness. We used SIS and SES scores of 62…”
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Influence of Androgen Deprivation Therapy on the PD-L1 Expression and Immune Activity in Prostate Cancer Tissue
Published in Frontiers in molecular biosciences (28-06-2022)“…Immune checkpoint inhibitors have become a promising new therapy for cancer treatment. However, due to prostate cancer’s high heterogeneity and…”
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Influence of Systemic Therapy on the Expression and Activity of Selected STAT Proteins in Prostate Cancer Tissue
Published in Life (Basel, Switzerland) (06-02-2022)“…Signal Transducer and Activator of Transcription (STAT) proteins have been identified as drivers of prostate cancer (PCa) progression and development of…”
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10
Master switches of T-cell activation and differentiation
Published in The European respiratory journal (01-04-2007)“…T-cells play a central role in allergic airway diseases such as bronchial asthma. The imbalance between allergen-specific pro-inflammatory and pro-allergic…”
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Gray matter anomalies in pedophiles with and without a history of child sexual offending
Published in Translational psychiatry (16-05-2017)“…Pedophilia is a psychiatric disorder that is inter-related with but distinct from child sexual offending (CSO). Neural alterations reportedly contribute to…”
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12
Coevolution of male and female reproductive traits in a simultaneously hermaphroditic land snail
Published in Journal of evolutionary biology (01-03-2006)“…Inter‐ and intraspecific studies in gonochoristic animals reveal a covariation between sperm characteristics and the size of the female reproductive tract,…”
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T-cell co-stimulatory molecules: novel targets for the treatment of allergic airway disease
Published in The European respiratory journal (01-08-2007)“…The first two articles in this series discussed the fundamental concept of T-cell co-stimulation as a key event in the induction of any immune response, in…”
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T-cell co-stimulatory molecules: their role in allergic immune reactions
Published in The European respiratory journal (01-06-2007)“…The development of allergic diseases, such as allergic asthma, depends upon the initiation and maintenance of T-helper cell type-2-skewed allergen-specific…”
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15
Human face processing is tuned to sexual age preferences
Published in Biology letters (2005) (01-05-2014)“…Human faces can motivate nurturing behaviour or sexual behaviour when adults see a child or an adult face, respectively. This suggests that face processing is…”
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EP 80. Sexual processing of pedophilic patients and healthy controls and the role of its metabolic markers – A fMRI and MRS study
Published in Clinical neurophysiology (01-09-2016)“…Introduction We aimed to investigate differential activation patterns in brain areas subserving attentional control of behavior and perception of salient…”
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Metabolic changes during prostate cancer development and progression
Published in Journal of cancer research and clinical oncology (01-05-2023)“…Metabolic reprogramming has been recognised as a hallmark in solid tumours. Malignant modification of the tumour’s bioenergetics provides energy for tumour…”
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The association of sexual preference and dynamic risk factors with undetected child pornography offending
Published in The journal of sexual aggression (02-01-2017)“…The risk for using child abuse images (CAI) is difficult to assess, especially as it mostly remains undetected by legal authorities. The present study…”
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Abnormal amygdala functional connectivity during an fMRI expectancy task in pedophilia
Published in European psychiatry (01-03-2016)“…Introduction Pedophilia is a disorder where sexual preferences of adults are directed towards children. This disorder impacts society with 1–2 out of every 10…”
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Hebephilia as a sexual disorder
Published in Fortschritte der Neurologie-Psychiatrie (01-02-2015)“…The term "hebephilia" describes the sexual preference for minors at an early pubertal body age. For most clinicians the definition of hebephilia is not obvious…”
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