Search Results - "Beier, D.R"

Ttc21b is required to restrict sonic hedgehog activity in the developing mouse forebrain by Stottmann, R.W., Tran, P.V., Turbe-Doan, A., Beier, D.R.

“…Organizing centers in the developing brain provide an assortment of instructive patterning cues, including Sonic hedgehog ( Shh). Here we characterize the…”
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A mutation in Tubb2b, a human polymicrogyria gene, leads to lethality and abnormal cortical development in the mouse by Stottmann, R W, Donlin, M, Hafner, A, Bernard, A, Sinclair, D A, Beier, D R

“…Human cortical malformations, including lissencephaly, polymicrogyria and other diseases of neurodevelopment, have been associated with mutations in…”
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Identification of a Van der Woude syndrome mutation in the cleft palate 1 mutant mouse by Stottmann, R.W., Bjork, B.C., Doyle, J.B., Beier, D.R.

“…Mutations in Interferon Regulatory Factor 6 (IRF6) have been identified in two human allelic syndromes with cleft lip and/or palate: Van der Woude (VWS) and…”
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Characterization and chromosome location of the mouse link protein gene (Crtl1) by Deák, F, Mátés, L, Krysan, K, Liu, Z, Szabó, P E, Mann, J R, Beier, D R, Kiss, I

“…Link protein (LP) plays an essential role in endochondral bone formation by stabilizing the supramolecular assemblies of aggrecan and hyaluronan. We have…”
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Mouse Eya homologues of the Drosophila eyes absent gene require Pax6 for expression in lens and nasal placode by Xu, P X, Woo, I, Her, H, Beier, D R, Maas, R L

“…We have identified and mapped three members of a new family of vertebrate genes, designated Eya1, Eya2 and Eya3, which share high sequence similarity with the…”
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A fibrillar collagen gene, Col11a1, is essential for skeletal morphogenesis by Li, Y, Lacerda, D.A, Warman, M.L, Beier, D.R, Yoshioka, H, Ninomiya, Y, Oxford, J.T, Morris, N.P, Andrikopoulos, K, Ramirez, F, Wardell, B.B, Lifferth, G.D, Teuscher, C, Woodward, S.R, Taylor, B.A, Seegmiller, R.E, Olsen, B.R

“…Mice that are homozygous for the autosomal recessive chondrodysplasia ( cho) mutation die at birth with abnormalities in cartilage of limbs, ribs, mandible,…”
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Genome-wide SNP analysis of Tg.AC transgenic mice reveals an oncogenic collaboration between v-Ha-ras and Ink4a, which is absent in p53 deficiency by Leder, A, McMenamin, J, Zhou, F, Moran, J L, Beier, D R, Leder, P

“…Oncogenesis is a progressive process often involving collaboration between various oncogenes and tumor suppressors. To identify those genes that collaborate…”
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Genomic structure and refined chromosomal localization of the mouse Ptch2 gene by Fröhlich, L, Liu, Z, Beier, D R, Lanske, B

“…The vertebrate Patched 2 (Ptch2) gene encodes a putative membrane-embedded protein which may have roles in Hedgehog signaling during development and in…”
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Genetic mapping of the Na(+)-taurocholate cotransporting polypeptide to mouse chromosome 12 by Green, R M, Ananthanarayanan, M, Suchy, F J, Beier, D R

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An integrated genetic and physical map of the 650-kb region containing the congenital polycystic kidney (cpk) locus on mouse chromosome 12 by Mrug, M, Green, W J, DasGupta, S, Beier, D R, Lu, W, D'Eustachio, P, Guay-Woodford, L M

“…Mice homozygous for the congenital polycystic kidney (cpk) mutation develop a rapidly progressive form of polycystic kidney disease. We report an integrated…”
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Conservation of dishevelled structure and function between flies and mice: isolation and characterization of Dvl2 by Klingensmith, J., Yang, Y., Axelrod, J.D., Beier, D.R., Perrimon, N., Sussman, D.J.

“…The segment polarity gene dishevelled (dsh) of Drosophila is required for pattern formation of the embryonic segments and the adult imaginal discs.dsh encodes…”
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