Search Results - "Beidler, Catherine"

Influence of physiochemical properties on the subcutaneous absorption and bioavailability of monoclonal antibodies by Datta-Mannan, Amita, Estwick, Selina, Zhou, Chen, Choi, Hiuwan, Douglass, Nicole E, Witcher, Derrick R, Lu, Jirong, Beidler, Catherine, Millican, Rohn

“…Many therapeutic monoclonal antibodies (mAbs) were initially developed for intravenous (IV) administration. As a means to improve mAb drug-ability and the…”
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Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody by Boyles, Jeffrey S, Beidler, Catherine B, Strifler, Beth A, Girard, Daniel S, Druzina, Zhanna, Durbin, Jim D, Swearingen, Michelle L, Lee, Linda N, Kikly, Kristine, Chintharlapalli, Sudhakar, Witcher, Derrick R

“…CXCR1 and CXCR2 signaling play a critical role in neutrophil migration, angiogenesis, and tumorigenesis and are therefore an attractive signaling axis to…”
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Generation and activity of a humanized monoclonal antibody that selectively neutralizes the epidermal growth factor receptor ligands transforming growth factor-α and epiregulin by Beidler, Catherine B, Petrovan, Ramona J, Conner, Elaine M, Boyles, Jeffrey S, Yang, Derek D, Harlan, Shannon M, Chu, Shaoyou, Ellis, Bernice, Datta-Mannan, Amita, Johnson, Robert L, Stauber, Anja, Witcher, Derrick R, Breyer, Matthew D, Heuer, Josef G

“…At least seven distinct epidermal growth factor (EGF) ligands bind to and activate the EGF receptor (EGFR). This activation plays an important role in the…”
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Generation and Characterization of Mirikizumab, a Humanized Monoclonal Antibody Targeting the p19 Subunit of IL-23 by Steere, Boyd, Beidler, Catherine, Martin, Andrea, Bright, Stu, Kikly, Kristy, Benschop, Robert J.

“…Interleukin (IL)-23 exists as a heterodimer consisting of p19 and p40 and is a key cytokine for promoting inflammatory responses in a variety of target organs…”
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Influence of physiochemical properties on the subcutaneous absorption and bioavailability of monoclonal antibodies by Datta-Mannan, Amita, Estwick, Selina, Zhou, Chen, Choi, Hiuwan, Douglass, Nicole E., Witcher, Derrick R., Lu, Jirong, Beidler, Catherine, Millican, Rohn

“…Many therapeutic monoclonal antibodies (mAbs) were initially developed for intravenous (IV) administration. As a means to improve mAb drug-ability and the…”
Get full text

Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody by Boyles, Jeffrey S., Beidler, Catherine B., Strifler, Beth A., Girard, Daniel S., Druzina, Zhanna, Durbin, Jim D., Swearingen, Michelle L., Lee, Linda N., Kikly, Kristine, Chintharlapalli, Sudhakar, Witcher, Derrick R.

“…CXCR1 and CXCR2 signaling play a critical role in neutrophil migration, angiogenesis, and tumorigenesis and are therefore an attractive signaling axis to…”
Get full text