Search Results - "Beißbarth, T"

Long‐term prognostic impact of surgical complications in the German Rectal Cancer Trial CAO/ARO/AIO‐94 by Sprenger, T., Beißbarth, T., Sauer, R., Tschmelitsch, J., Fietkau, R., Liersch, T., Hohenberger, W., Staib, L., Gaedcke, J., Raab, H.‐R., Rödel, C., Ghadimi, M.

“…Background The influence of postoperative complications on survival in patients with locally advanced rectal cancer undergoing combined modality treatment is…”
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BITES: balanced individual treatment effect for survival data by Schrod, S, Schäfer, A, Solbrig, S, Lohmayer, R, Gronwald, W, Oefner, P J, Beißbarth, T, Spang, R, Zacharias, H U, Altenbuchinger, M

“…Abstract Motivation Estimating the effects of interventions on patient outcome is one of the key aspects of personalized medicine. Their inference is often…”
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TNF-α mediates mitochondrial uncoupling and enhances ROS-dependent cell migration via NF-κB activation in liver cells by Kastl, L., Sauer, S.W., Ruppert, T., Beissbarth, T., Becker, M.S., Süss, D., Krammer, P.H., Gülow, K.

“…•TNF-α induces mitochondrial ROS production in liver cells.•ROS release involves complex I and/or complex III in liver cells.•TNF-α acts as mild uncoupler of…”
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Master Regulators Associated with Poor Prognosis in Glioblastoma Multiforme by Kalya, M., Beißbarth, T., Kel, A. E.

“…Glioblastoma multiforme is a highly malignant brain tumor with average survival time of 15 months. Less than 2% of the patients survive beyond 36 months. To…”
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WNT5A: a motility-promoting factor in Hodgkin lymphoma by Linke, F, Zaunig, S, Nietert, M M, von Bonin, F, Lutz, S, Dullin, C, Janovská, P, Beissbarth, T, Alves, F, Klapper, W, Bryja, V, Pukrop, T, Trümper, L, Wilting, J, Kube, D

“…Classical Hodgkin lymphoma (cHL) has a typical clinical manifestation, with dissemination involving functionally neighboring lymph nodes. The factors involved…”
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Multimorbidity as a predictor for inpatient admission in clinical emergency and acute medicine : Single-center cluster analysis by Grüneberg, E, Fliedner, R, Beißbarth, T, von Arnim, C A F, Blaschke, S

“…Parallel to demographic trends, an increase of multimorbid patients in emergency and acute medicine is prominent. To define easily applicable criteria for the…”
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Acute and Long-Term Hemodynamic Effects of MitraClip Implantation on a Preexisting Secondary Right Heart Failure by Baldus, S., Treede, H., Von Bardeleben, R. S., Blankenberg, Stefan, Schillinger, Wolfgang, Rudolph, V., Tichelbäcker, T., Beißbarth, T., Bleckmann, A., Puls, M., Beuthner, B. E., Lubos, Edith, Hünlich, M., Schäfer, Ulrich

“…Positive results of MitraClip in terms of improvement in clinical and left ventricular parameters have been described in detail. However, long-term effects on…”
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Towards outcome-based programme evaluation: Using student comparative self-assessments to determine teaching effectiveness by Raupach, T., Münscher, C., Beißbarth, T., Burckhardt, G., Pukrop, T.

“…Background: Programme evaluation of medical education should be multi-dimensional. While structural and organisational aspects of teaching are frequently…”
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β-catenin-independent WNT signaling in basal-like breast cancer and brain metastasis by KLEMM, F, BLECKMANN, A, KRAMER, F, BEISSBARTH, T, STADELMANN, C, BINDER, C, PUKROP, T, SIAM, L, CHUANG, H. N, RIETKÖTTER, E, BEHME, D, SCHULZ, M, SCHAFFRINSKI, M, SCHINDLER, S, TRÜMPER, L

“…A role of WNT signaling for primary breast cancers of the basal-like subtype and as a predictor of brain metastasis has been described. However, a responsible…”
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Social defeat leads to changes in the endocannabinoid system: An overexpression of calreticulin and motor impairment in mice by Tomas-Roig, J., Piscitelli, F., Gil, V., del Río, J.A., Moore, T.P., Agbemenyah, H., Salinas-Riester, G., Pommerenke, C., Lorenzen, S., Beißbarth, T., Hoyer-Fender, S., Di Marzo, V., Havemann-Reinecke, U.

“…•Motor coordination and motor learning are compromised in social defeat mice.•After three weeks of social stress, the cerebellum of stressed mice compared to…”
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Microenvironmental interactions between endothelial and lymphoma cells: a role for the canonical WNT pathway in Hodgkin lymphoma by Linke, F, Harenberg, M, Nietert, M M, Zaunig, S, von Bonin, F, Arlt, A, Szczepanowski, M, Weich, H A, Lutz, S, Dullin, C, Janovská, P, Krafčíková, M, Trantírek, L, Ovesná, P, Klapper, W, Beissbarth, T, Alves, F, Bryja, V, Trümper, L, Wilting, J, Kube, D

“…The interaction between vascular endothelial cells (ECs) and cancer cells is of vital importance to understand tumor dissemination. A paradigmatic cancer to…”
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The putative oncogene CEP72 inhibits the mitotic function of BRCA1 and induces chromosomal instability by Lüddecke, S, Ertych, N, Stenzinger, A, Weichert, W, Beissbarth, T, Dyczkowski, J, Gaedcke, J, Valerius, O, Braus, G H, Kschischo, M, Bastians, H

“…BRCA1 is a tumor-suppressor gene associated with, but not restricted to, breast and ovarian cancer and implicated in various biological functions. During…”
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Relevance of surgery in patients with non-variceal upper gastrointestinal bleeding by Dango, S., Beißbarth, T., Weiss, E., Seif Amir Hosseini, A., Raddatz, D., Ellenrieder, V., Lotz, J., Ghadimi, B. M., Beham, A.

“…Introduction Upper GI bleeding remains one of the most common emergencies with a substantial overall mortality rate of up to 30%. In severe ill patients, death…”
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Nuclear LEF1/TCF4 correlate with poor prognosis but not with nuclear β-catenin in cerebral metastasis of lung adenocarcinomas by Bleckmann, A., Siam, L., Klemm, F., Rietkötter, E., Wegner, Chr, Kramer, F., Beissbarth, T., Binder, C., Stadelmann, Chr, Pukrop, T.

“…An essential function of the transcription factors LEF1/TCF4 in cerebral metastases of lung adenocarcinomas has been described in mouse models, suggesting a…”
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Strong EGFR signaling in cell line models of ERBB2-amplified breast cancer attenuates response towards ERBB2-targeting drugs by Henjes, F, Bender, C, von der Heyde, S, Braun, L, Mannsperger, H A, Schmidt, C, Wiemann, S, Hasmann, M, Aulmann, S, Beissbarth, T, Korf, U

“…Increasing the efficacy of targeted cancer therapies requires the identification of robust biomarkers suitable for patient stratification. This study focused…”
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UDP glucuronosyltransferase 1A expression levels determine the response of colorectal cancer cells to the heat shock protein 90 inhibitor ganetespib by Landmann, H, Proia, D A, He, S, Ogawa, L S, Kramer, F, Beißbarth, T, Grade, M, Gaedcke, J, Ghadimi, M, Moll, U, Dobbelstein, M

“…HSP90 inhibition represents a promising route to cancer therapy, taking advantage of cancer cell-inherent proteotoxic stress. The HSP90-inhibitor ganetespib…”
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Bilobar spreading of colorectal liver metastases does not significantly affect survival after R0 resection in the era of interdisciplinary multimodal treatment by Homayounfar, K., Bleckmann, A., Conradi, L. C., Sprenger, T., Beissbarth, T., Lorf, T., Niessner, M., Sahlmann, C. O., Meller, J., Becker, H., Liersch, T., Ghadimi, B. M.

“…Purpose Bilobar colorectal liver metastases (CRLM) are often considered incurable or associated with poor prognosis even after R0 resection. In this…”
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847 Identification of a Biomarker Signature to Predict the Need for Chemotherapy in Patients With Hormone Receptor Positive Breast Cancer by Korf, U, Sonntag, J, Bender, C, Wiemann, S, Aulmann, S, Sinn, P, Burwinkel, B, Schneeweiss, A, Beissbarth, T

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Elucidation of B cell receptor signaling in Burkitt’s lymphoma reveals novel signaling nodes with potential therapeutic relevance by Oellerich, T, Corso, J, Beck, J, Doebele, C, Wachter, A, Lenz, C, Bohnenberger, H, Beissbarth, T, Gökbuget, N, Schütz, E, Serve, H, Urlaub, H

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6126 POSTER Thymidylate Synthase as Biomarker in Rectal Cancer Patients After 5-FU-based Radiochemotherapy – Evaluation of the Prognostic Capacity in Pre-treatment Biopsies and Resected Adenocarcinoma by Conradi, L.C, Bleckmann, A, Sprenger, T, Schirmer, M, Homayounfar, K, Wolff, H.A, Becker, H, Ghadimi, B.M, Beissbarth, T, Liersch, T

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