Search Results - "Bei, Yanxia"

Functional Proteomics Reveals the Biochemical Niche of C. elegans DCR-1 in Multiple Small-RNA-Mediated Pathways by Duchaine, Thomas F., Wohlschlegel, James A., Kennedy, Scott, Bei, Yanxia, Conte, Darryl, Pang, KaMing, Brownell, Daniel R., Harding, Sandra, Mitani, Shohei, Ruvkun, Gary, Yates, John R., Mello, Craig C.

“…In plants, animals, and fungi, members of the Dicer family of RNase III-related enzymes process double-stranded RNA (dsRNA) to initiate small-RNA-mediated…”
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Spindle-E cycling between nuage and cytoplasm is controlled by Qin and PIWI proteins by Andress, Arlise, Bei, Yanxia, Fonslow, Bryan R, Giri, Ritika, Wu, Yilong, Yates, 3rd, John R, Carthew, Richard W

“…Transposable elements (TEs) are silenced in germ cells by a mechanism in which PIWI proteins generate and use PIWI-interacting ribonucleic acid (piRNA) to…”
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Overcoming variant mutation-related impacts on viral sequencing and detection methodologies by Bei, Yanxia, Pinet, Kaylinnette, Vrtis, Kyle B., Borgaro, Janine G., Sun, Luo, Campbell, Matthew, Apone, Lynne, Langhorst, Bradley W., Nichols, Nicole M.

“…Prompt and accurate pathogen identification, by diagnostics and sequencing, is an effective tool for tracking and potentially curbing pathogen spread. Targeted…”
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The Conserved Kinases CDK-1, GSK-3, KIN-19, and MBK-2 Promote OMA-1 Destruction to Regulate the Oocyte-to-Embryo Transition in C. elegans by Shirayama, Masaki, Soto, Martha C., Ishidate, Takao, Kim, Soyoung, Nakamura, Kuniaki, Bei, Yanxia, van den Heuvel, Sander, Mello, Craig C.

“…At the onset of embryogenesis, key developmental regulators called determinants are activated asymmetrically to specify the body axes and tissue layers. In C…”
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Wnt Signaling and an APC-Related Gene Specify Endoderm in Early C. elegans Embryos by Rocheleau, Christian E, Downs, William D, Lin, Rueyling, Wittmann, Claudia, Bei, Yanxia, Cha, Yoon-Hee, Ali, Mussa, Priess, James R, Mello, Craig C

“…In a 4-cell stage C. elegans embryo, signaling by the P2 blastomere induces anterior–posterior polarity in the adjacent EMS blastomere, leading to endoderm…”
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SRC-1 and Wnt Signaling Act Together to Specify Endoderm and to Control Cleavage Orientation in Early C. elegans Embryos by Bei, Yanxia, Hogan, Jennifer, Berkowitz, Laura A., Soto, Martha, Rocheleau, Christian E., Pang, Ka Ming, Collins, John, Mello, Craig C.

“…In early C. elegans embryos, signaling between a posterior blastomere, P2, and a ventral blastomere, EMS, specifies endoderm and orients the division axis of…”
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MOM-4, a MAP Kinase Kinase Kinase–Related Protein, Activates WRM-1/LIT-1 Kinase to Transduce Anterior/Posterior Polarity Signals in C. elegans by Shin, Tae Ho, Yasuda, Jun, Rocheleau, Christian E., Lin, Rueyling, Soto, Martha, Bei, Yanxia, Davis, Roger J., Mello, Craig C.

“…In C. elegans, a Wnt/WG-like signaling pathway downregulates the TCF/LEF-related protein, POP-1, to specify posterior cell fates. Effectors of this signaling…”
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The Conserved Kinases CDK-1, GSK-3, KIN-19, and MBK-2 Promote OMA-1 Destruction to Regulate the Oocyte-to-Embryo Transition in C. elegans by Shirayama, Masaki, Soto, Martha C., Ishidate, Takao, Kim, Soyoung, Nakamura, Kuniaki, Bei, Yanxia, van den Heuvel, Sander, Mello, Craig C.

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Non-templated addition and template switching by Moloney murine leukemia virus (MMLV)-based reverse transcriptases co-occur and compete with each other by Wulf, Madalee G., Maguire, Sean, Humbert, Paul, Dai, Nan, Bei, Yanxia, Nichols, Nicole M., Corrêa, Ivan R., Guan, Shengxi

“…Single-cell RNA-Seq (scRNA-Seq) has led to an unprecedented understanding of gene expression and regulation in individual cells. Many scRNA-Seq approaches rely…”
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Abstract 4883: A novel target capture approach for next generation sequencing and its application to oncogenic mutation detection by Bei, Yanxia, Galvin, Brendan, Richard, Cynthia

“…Abstract Due to the complexity and heterogeneity of cancer genetics, next generation sequencing has played an increasingly important role in cancer diagnosis,…”
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Analysis of the C. elegans Argonaute Family Reveals that Distinct Argonautes Act Sequentially during RNAi by Yigit, Erbay, Batista, Pedro J., Bei, Yanxia, Pang, Ka Ming, Chen, Chun-Chieh G., Tolia, Niraj H., Joshua-Tor, Leemor, Mitani, Shohei, Simard, Martin J., Mello, Craig C.

“…Argonaute (AGO) proteins interact with small RNAs to mediate gene silencing. C. elegans contains 27 AGO genes, raising the question of what roles these genes…”
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Abstract 3620: Enhancing clinical utility of NGS with reduced bias, low DNA input, library construction by Apone, Lynne, Liu, Pingfang, Panchapakesa, Vaish, Rodriguez, Deyra, Duggan, Karen, Keerthana, Krishnan, Nichols, Nicole, Bei, Yanxia, Menin, Julie, Langhorst, Brad, Sumner, Christine, Chater, Christine, Bybee, Joanna, Mazzola, Laurie, Rivizzigno, Danielle, Stewart, Fiona, Dimalanta, Eileen, Davis, Theodore

“…Abstract Early detection and diagnosis of cancer substantially increases the likelihood for successful treatment. Tools that aid in detecting and diagnosing…”
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Posttranscriptional gene silencing by Pressman, Sigal, Bei, Yanxia, Carthew, Richard

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SnapShot: Posttranscriptional Gene Silencing by Pressman, Sigal, Bei, Yanxia, Carthew, Richard

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SnapShot: Small RNA-Mediated Epigenetic Modifications by Bei, Yanxia, Pressman, Sigal, Carthew, Richard

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Wnt signaling drives WRM-1/beta-catenin asymmetries in early C. elegans embryos by Nakamura, Kuniaki, Kim, Soyoung, Ishidate, Takao, Bei, Yanxia, Pang, Kaming, Shirayama, Masaki, Trzepacz, Chris, Brownell, Daniel R, Mello, Craig C

“…beta-Catenin regulates cell adhesion and cellular differentiation during development, and misregulation of beta-catenin contributes to numerous forms of cancer…”
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HAT activity is essential for CBP-1-dependent transcription and differentiation in Caenorhabditis elegans by Victor, Martin, Bei, Yanxia, Gay, Frédérique, Calvo, Dominica, Mello, Craig, Shi, Yang

“…The p300/CBP family of transcriptional coactivators possesses multiple functional domains, including a histone acetyltransferase (HAT) and several activation…”
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