Search Results - "Behrens, Ryan T"

Retroviral hijacking of host transport pathways for genome nuclear export by Behrens, Ryan T, Sherer, Nathan M

“…Recent advances in the study of virus-cell interactions have improved our understanding of how viruses that replicate their genomes in the nucleus (e.g.,…”
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Potent broadly neutralizing antibodies mediate efficient antibody-dependent phagocytosis of HIV-infected cells by Snow, Brian J, Keles, Nida K, Grunst, Michael W, Janaka, Sanath Kumar, Behrens, Ryan T, Evans, David T

“…Antibody-dependent cellular phagocytosis (ADCP) has been implicated in protection against HIV-1. However, methods for measuring ADCP currently rely on the…”
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Exploiting a rodent cell block for intrinsic resistance to HIV-1 gene expression in human T cells by Behrens, Ryan T, Rajashekar, Jyothi Krishnaswamy, Bruce, James W, Evans, 3rd, Edward L, Hansen, Amelia M, Salazar-Quiroz, Natalia, Simons, Lacy M, Ahlquist, Paul, Hultquist, Judd F, Kumar, Priti, Sherer, Nathan M

“…Unlike humans, mice are unable to support HIV-1 infection. This is due, in part, to a constellation of defined minor, species-specific differences in conserved…”
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HIV RGB: Automated Single-Cell Analysis of HIV-1 Rev-Dependent RNA Nuclear Export and Translation Using Image Processing in KNIME by Evans, 3rd, Edward L, Pocock, Ginger M, Einsdorf, Gabriel, Behrens, Ryan T, Dobson, Ellen T A, Wiedenmann, Marcel, Birkhold, Christian, Ahlquist, Paul, Eliceiri, Kevin W, Sherer, Nathan M

“…Single-cell imaging has emerged as a powerful means to study viral replication dynamics and identify sites of virus−host interactions. Multivariate aspects of…”
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Mediator complex subunit 12 is a gatekeeper of SARS-CoV-2 infection in breast cancer cells by Zhang, Shengjie, Liu, Fabao, Halfmann, Peter, Behrens, Ryan T., Liu, Peng, Mcilwain, Sean J., Ong, Irene M., Donahue, Kristine, Wang, Yidan, Kawaoka, Yoshihiro, Sherer, Nathan, Xu, Wei

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Substitutions in Nef That Uncouple Tetherin and SERINC5 Antagonism Impair Simian Immunodeficiency Virus Replication in Primary Rhesus Macaque Lymphocytes by Janaka, Sanath Kumar, Snow, Brian J, Behrens, Ryan T, Evans, David T

“…Most simian immunodeficiency viruses (SIVs) use Nef to counteract restriction by the tetherin proteins of their nonhuman primate hosts. In addition to…”
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Human lysyl-tRNA synthetase phosphorylation promotes HIV-1 proviral DNA transcription by Tang, Yingke, Behrens, Ryan T, St Gelais, Corine, Wu, Siqi, Vivekanandan, Saravanan, Razin, Ehud, Fang, Pengfei, Wu, Li, Sherer, Nathan, Musier-Forsyth, Karin

“…Abstract Human lysyl-tRNA synthetase (LysRS) was previously shown to be re-localized from its normal cytoplasmic location in a multi-aminoacyl-tRNA synthetase…”
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Nuclear Export Signal Masking Regulates HIV-1 Rev Trafficking and Viral RNA Nuclear Export by Behrens, Ryan T, Aligeti, Mounavya, Pocock, Ginger M, Higgins, Christina A, Sherer, Nathan M

“…HIV-1's Rev protein forms a homo-oligomeric adaptor complex linking viral RNAs to the cellular CRM1/Ran-GTP nuclear export machinery through the activity of…”
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Robust engraftment of fetal nonhuman primate CD34‐positive cells in immune‐deficient mice by Little, Christopher J., Haynes, William J., Huang, Liupei, Daffada, Cross M., Wolfe, Bryce K., Perrin, Elizabeth, Simpson, John A., Kropp Schmidt, Jenna A., Hinkle, Hayly M., Keding, Logan T., Behrens, Ryan T., Evans, David T., Kaufman, Dixon B., Thomson, James A., Golos, Thaddeus G., Brown, Matthew E.

“…Nonhuman primates (NHPs) represent one of the most important models for preclinical studies of novel biomedical interventions. In contrast with small animal…”
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Cooperativity among Rev-associated nuclear export signals regulates HIV-1 gene expression and is a determinant of virus species tropism by Aligeti, Mounavya, Behrens, Ryan T, Pocock, Ginger M, Schindelin, Johannes, Dietz, Christian, Eliceiri, Kevin W, Swanson, Chad M, Malim, Michael H, Ahlquist, Paul, Sherer, Nathan M

“…Murine cells exhibit a profound block to HIV-1 virion production that was recently mapped to a species-specific structural attribute of the murine version of…”
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