Search Results - "Behrens, Maria"

Flavonols and Flavones as Potential anti-Inflammatory, Antioxidant, and Antibacterial Compounds by Chagas, Maria do Socorro S., Behrens, Maria D., Moragas-Tellis, Carla J., Penedo, Gabriela X. M., Silva, Adriana R., Gonçalves-de-Albuquerque, Cassiano F.

“…Plant preparations have been used to treat various diseases and discussed for centuries. Research has advanced to discover and identify the plant components…”
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Mitochondrial permeability transition pore contributes to mitochondrial dysfunction in fibroblasts of patients with sporadic Alzheimer's disease by Pérez, María José, Ponce, Daniela P., Aranguiz, Alejandra, Behrens, Maria I., Quintanilla, Rodrigo A.

“…In the last few decades, many reports have suggested that mitochondrial function impairment is a hallmark of Alzheimer's disease (AD). Although AD is a…”
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Brain clocks capture diversity and disparities in aging and dementia across geographically diverse populations by Moguilner, Sebastian, Baez, Sandra, Hernandez, Hernan, Migeot, Joaquín, Legaz, Agustina, Gonzalez-Gomez, Raul, Farina, Francesca R, Prado, Pavel, Cuadros, Jhosmary, Tagliazucchi, Enzo, Altschuler, Florencia, Maito, Marcelo Adrián, Godoy, María E, Cruzat, Josephine, Valdes-Sosa, Pedro A, Lopera, Francisco, Ochoa-Gómez, John Fredy, Hernandez, Alfredis Gonzalez, Bonilla-Santos, Jasmin, Gonzalez-Montealegre, Rodrigo A, Anghinah, Renato, d'Almeida Manfrinati, Luís E, Fittipaldi, Sol, Medel, Vicente, Olivares, Daniela, Yener, Görsev G, Escudero, Javier, Babiloni, Claudio, Whelan, Robert, Güntekin, Bahar, Yırıkoğulları, Harun, Santamaria-Garcia, Hernando, Lucas, Alberto Fernández, Huepe, David, Di Caterina, Gaetano, Soto-Añari, Marcio, Birba, Agustina, Sainz-Ballesteros, Agustin, Coronel-Oliveros, Carlos, Yigezu, Amanuel, Herrera, Eduar, Abasolo, Daniel, Kilborn, Kerry, Rubido, Nicolás, Clark, Ruaridh A, Herzog, Ruben, Yerlikaya, Deniz, Hu, Kun, Parra, Mario A, Reyes, Pablo, García, Adolfo M, Matallana, Diana L, Avila-Funes, José Alberto, Slachevsky, Andrea, Behrens, María I, Custodio, Nilton, Cardona, Juan F, Barttfeld, Pablo, Brusco, Ignacio L, Bruno, Martín A, Sosa Ortiz, Ana L, Pina-Escudero, Stefanie D, Takada, Leonel T, Resende, Elisa, Possin, Katherine L, de Oliveira, Maira Okada, Lopez-Valdes, Alejandro, Lawlor, Brian, Robertson, Ian H, Kosik, Kenneth S, Duran-Aniotz, Claudia, Valcour, Victor, Yokoyama, Jennifer S, Miller, Bruce, Ibanez, Agustin

“…Brain clocks, which quantify discrepancies between brain age and chronological age, hold promise for understanding brain health and disease. However, the…”
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Cancer History Avoids the Increase of Senescence Markers in Peripheral Cells of Amnestic Mild Cognitive Impaired Patients by SanMartín, Carol D, Salech, Felipe, Ponce, Daniela Paz, Concha-Cerda, Jorge, Romero-Hernández, Esteban, Liabeuf, Gianella, Rogers, Nicole K, Murgas, Paola, Bruna, Bárbara, More, Jamileth, Behrens, María I

“…Epidemiological studies show that having a history of cancer protects from the development of Alzheimer's Disease (AD), and vice versa, AD protects from…”
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Impact of social isolation and coping strategies in older adults with mild cognitive impairment during the covid-19 pandemic: A qualitative study by Farhang, Maryam, Miranda-Castillo, Claudia, Behrens, Maria Isabel, Castillo, Eduardo, Mosquera Amar, Sandra, Rojas, Graciela

“…The COVID-19 pandemic imposed a psychological burden on elderly and particularly individuals with cognitive impairment and dementia. Few studies have…”
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Mitochondrial Bioenergetics Is Altered in Fibroblasts from Patients with Sporadic Alzheimer's Disease by Pérez, María J, Ponce, Daniela P, Osorio-Fuentealba, Cesar, Behrens, Maria I, Quintanilla, Rodrigo A

“…The identification of an early biomarker to diagnose Alzheimer's disease (AD) remains a challenge. Neuropathological studies in animal and AD patients have…”
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Hereditary parkinsonism with dementia is caused by mutations in ATP13A2 , encoding a lysosomal type 5 P-type ATPase by Al-Din, Amir, Hillmer, Axel M, Gründemann, Jan, Goebel, Ingrid, Woods, C Geoffrey, Stiller, Barbara, Wriekat, Abdul-Latif, Heimbach, André, Mubaidin, Ammar F, Behrens, Maria I, Cid, L Pablo, Karsak, Meliha, Ramirez, Alfredo, Kubisch, Christian, Liss, Birgit, Hampshire, Dan, Roeper, Jochen

“…Neurodegenerative disorders such as Parkinson and Alzheimer disease cause motor and cognitive dysfunction and belong to a heterogeneous group of common and…”
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New Homoisoflavanes, a New Alkaloid and Spirostane Steroids from the Roots of Herreria montevidensis Klotzsch ex Griseb. (Herreriaceae) by Dutra-Behrens, María, Schmeda-Hirschmann, Guillermo

“…The roots of the South American vine Klotzsch ex Griseb. (Herreriaceae) are used in traditional medicine by several Amerindian groups of the Paraguayan Chaco…”
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Visual-spatial processing impairment in the occipital-frontal connectivity network at early stages of Alzheimer's disease by Plaza-Rosales, Iván, Brunetti, Enzo, Montefusco-Siegmund, Rodrigo, Madariaga, Samuel, Hafelin, Rodrigo, Ponce, Daniela P, Behrens, María Isabel, Maldonado, Pedro E, Paula-Lima, Andrea

“…Alzheimer's disease (AD) is the leading cause of dementia worldwide, but its pathophysiological phenomena are not fully elucidated. Many neurophysiological…”
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The autophagy protein Def8 is altered in Alzheimer's disease and Aβ42-expressing Drosophila brains by Oyarce-Pezoa, Sebastián, Rucatti, Guilherme Gischkow, Muñoz-Carvajal, Francisco, Sanhueza, Nicole, Gomez, Wileidy, Espinoza, Sandra, Leiva, Mario, García, Nicolás, Ponce, Daniela P., SanMartín, Carol D., Rojas-Rivera, Diego, Salvadores, Natalia, Behrens, Maria I., Woehlbier, Ute, Calegaro-Nassif, Melissa, Sanhueza, Mario

“…Alzheimer's disease (AD) is the most common neurodegenerative disorder, characterized by protein accumulation in the brain as a main neuropathological…”
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The Impact of a Yoga-Based Mindfulness Intervention versus Psycho-Educational Session for Older Adults with Mild Cognitive Impairment: The Protocol of a Randomized Controlled Trial by Farhang, Maryam, Rojas, Graciela, Martínez, Pablo, Behrens, Maria Isabel, Langer, Álvaro I, Diaz, Marcela, Miranda-Castillo, Claudia

“…There is a global agreement in the medical community that a significant proportion of dementia cases could be prevented or postponed. One of the factors behind…”
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Frizzled-1 receptor regulates adult hippocampal neurogenesis by Mardones, Muriel D, Andaur, Gabriela A, Varas-Godoy, Manuel, Henriquez, Jenny F, Salech, Felipe, Behrens, María Isabel, Couve, Andrés, Inestrosa, Nibaldo C, Varela-Nallar, Lorena

“…In the adult hippocampus new neurons are continuously generated from neural stem cells (NSCs) present at the subgranular zone of the dentate gyrus. This…”
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DEF8 and Autophagy-Associated Genes Are Altered in Mild Cognitive Impairment, Probable Alzheimer's Disease Patients, and a Transgenic Model of the Disease by Leyton, Esteban, Matus, Diego, Espinoza, Sandra, Benitez, José Matías, Cortés, Bastián I, Gomez, Wileidy, Arévalo, Nohela B, Murgas, Paola, Manque, Patricio, Woehlbier, Ute, Duran-Aniotz, Claudia, Hetz, Claudio, Behrens, María Isabel, SanMartín, Carol D, Nassif, Melissa

“…Disturbances in the autophagy/endolysosomal systems are proposed as early signatures of Alzheimer's disease (AD). However, few studies are available concerning…”
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A call for clinical trial globalization in Alzheimer's disease and related dementia by Llibre‐Guerra, Jorge J., Heavener, Anika, Brucki, Sonia Maria Dozzi, Marante, Juan Pablo Díaz, Pintado‐Caipa, Maritza, Chen, Yaohua, Behrens, María Isabel, Hardi, Angela, Admirall‐Sanchez, Arianna, Akinyemi, Rufus, Alladi, Suvarna, Dorsman, Karen A., Rodriguez‐Salgado, Ana M., Solorzano, Joel, Babulal, Ganesh M.

“…Background The burden of Alzheimer's disease and related dementia (ADRD) is projected to disproportionally impact low‐middle‐income countries (LMICs). However,…”
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Antileishmanial Activity of Flavones-Rich Fraction From Arrabidaea chica Verlot (Bignoniaceae) by Silva-Silva, João Victor, Moragas-Tellis, Carla Junqueira, Chagas, Maria do Socorro dos Santos, Souza, Paulo Victor Ramos de, Souza, Celeste da Silva Freitas de, Hardoim, Daiana de Jesus, Taniwaki, Noemi Nosomi, Moreira, Davyson de Lima, Dutra Behrens, Maria, Calabrese, Kátia da Silva, Almeida-Souza, Fernando

“…Acknowledging the need of identifying new compounds for the treatment of leishmaniasis, this study aimed to evaluate, from in vitro trials, the activity of…”
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Carajurin: a anthocyanidin from Arrabidaea chica as a potential biological marker of antileishmanial activity by Silva-Silva, João Victor, Moragas-Tellis, Carla J., Chagas, Maria S.S., Souza, Paulo Victor R., Moreira, Davyson L., de Souza, Celeste S.F., Teixeira, Kerolain F., Cenci, Arthur R., de Oliveira, Aldo S., Almeida-Souza, Fernando, Behrens, Maria D., Calabrese, Kátia S.

“…Leishmaniasis is a group of neglected tropical diseases whose treatment with antimonials bears limitations and has changed little in over 80 years. Medicinal…”
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Carajurin Induces Apoptosis in Leishmania amazonensis Promastigotes through Reactive Oxygen Species Production and Mitochondrial Dysfunction by Silva-Silva, João Victor, Moragas-Tellis, Carla J, Chagas, Maria S S, Souza, Paulo Victor R, Moreira, Davyson L, Hardoim, Daiana J, Taniwaki, Noemi N, Costa, Vanessa F A, Bertho, Alvaro L, Brondani, Daniela, Zapp, Eduardo, de Oliveira, Aldo Sena, Calabrese, Kátia S, Behrens, Maria D, Almeida-Souza, Fernando

“…Carajurin is the main constituent of species with reported anti- activity. However, its mechanism of action has not been described. This study investigated the…”
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Validation of a New HPLC-DAD Method to Quantify 3-Deoxyanthocyanidins Based on Carajurin in Medicinal Plants and for Chemical Ecology Studies by Souza, Paulo Victor R, Martins, Vanessa G F C, Chagas, Maria do Socorro S, Moragas-Tellis, Carla J, Behrens, Maria D, Moreira, Davyson L

“…Anthocyanidins are found in nature mainly as pelargonidin, cyanidin, peonidin, delphinidin, petunidin, and malvidin derivatives. These compounds are found free…”
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On the Role of Mining Exposure in Epigenetic Effects in Parkinson’s Disease by Castillo, Sebastian, Muñoz, Patricia, Behrens, Maria Isabel, Diaz-Grez, Fernando, Segura-Aguilar, Juan

“…To explore the possible influence of heavy metal mining on incidence of Parkinson’s disease (PD), global DNA methylation was assessed in blood samples from a…”
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Clinical spectrum of Kufor-Rakeb syndrome in the Chilean kindred with ATP13A2 mutations by Behrens, Maria I., Brüggemann, Norbert, Chana, Pedro, Venegas, Pablo, Kägi, Marianne, Parrao, Teresa, Orellana, Patricia, Garrido, Cristian, Rojas, Cecilia V., Hauke, Jan, Hahnen, Eric, González, Rafael, Seleme, Nicolas, Fernández, Verónica, Schmidt, Alexander, Binkofski, Ferdinand, Kömpf, Detlef, Kubisch, Christian, Hagenah, Johann, Klein, Christine, Ramirez, Alfredo

“…We report the clinical features of the original Chilean family with Kufor‐Rakeb syndrome (KRS) that led to the discovery of the ATP13A2 gene at the PARK9…”
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