Search Results - "Behnam, Keyvan"
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Bone Morphogenetic Protein Binding Peptide Mechanism and Enhancement of Osteogenic Protein-1 Induced Bone Healing
Published in Spine (Philadelphia, Pa. 1976) (01-11-2010)“…In vitro and in vivo evaluation of BBP interactions with BMP. To explore bone morphogenetic protein-binding peptide (BBP)'s mechanism of action, investigate an…”
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BMP binding peptide: a BMP-2 enhancing factor deduced from the sequence of native bovine bone morphogenetic protein/non-collagenous protein
Published in Journal of orthopaedic research (2005)“…Forty years ago, Marshall Urist described a partially purified extract of demineralized bone matrix which induced the formation of ectopic bone. This…”
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Alanine-scanning mutations of the BMP-binding domain of recombinant secretory bovine spp24 affect cytokine binding
Published in Connective tissue research (01-12-2010)“…Secreted phosphoprotein 24 kDa (spp24) is a bone morphogenetic protein (BMP)/transforming growth factor-β cytokine-binding protein. The spp24…”
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Recombinant Expression, Isolation, and Proteolysis of Extracellular Matrix-Secreted Phosphoprotein-24 kDa
Published in Connective Tissue Research (01-01-2007)“…Secreted phosphoprotein-24 kDa (spp24) is an extracellular matrix protein first cloned from bone. Bovine spp24 is transcribed as a 203 amino acid residue…”
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BMP Stimulation of Alkaline Phosphatase Activity in Pluripotent Mouse C2C12 Cells is Inhibited by Dermatopontin, One of the Most Abundant Low Molecular Weight Proteins in Demineralized Bone Matrix
Published in Connective Tissue Research (2006)“…Demineralized bone matrix (DBM) is a complex mixture of osteoinductive bone morphogenetic proteins (BMPs), as well as BMP-binding proteins that regulate BMP…”
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Identification and characterization of valosin-containing protein (VCP/p97) in untransformed osteoblast-like cells
Published in Journal of orthopaedic research (01-05-2005)“…A 97-kDa protein called valosin-containing protein (VCP) has been implicated in osteosarcoma metastasis and Paget’s disease of bone, two conditions that…”
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Identification of the molecular chaperone alpha B-crystallin in demineralized bone powder and osteoblast-like cells
Published in Journal of orthopaedic research (01-11-2002)“…Bone is subjected to a variety of physiological, as well as cell-deforming biomechanical stresses, including hydrostatic compression and fluid flow. However,…”
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Alkali-urea extraction of demineralized bone matrix removes noggin, an inhibitor of bone morphogenetic proteins
Published in Connective tissue research (01-01-2004)“…Demineralized bone matrix (DBM) and native bone morphogenetic protein (nBMP) are complex mixtures of non-collagenous bone proteins. These mixtures contain many…”
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Bone morphogenetic protein–2 activity is regulated by secreted phosphoprotein–24 kd, an extracellular pseudoreceptor, the gene for which maps to a region of the human genome important for bone quality
Published in Metabolism, clinical and experimental (01-05-2009)“…Abstract The material properties of bone are the sum of the complex and interrelated anabolic and catabolic processes that modulate formation and turnover. The…”
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Carboxy terminus of secreted phosphoprotein-24 kDa (spp24) is essential for full inhibition of BMP-2 activity
Published in Journal of orthopaedic research (01-09-2010)“…Secreted phosphoprotein‐24 kDa (spp24) is a bone morphogenetic protein (BMP)‐binding protein isolated from bone. It exists in a number of size forms and is…”
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Full-length bovine spp24 [spp24 (24-203)] inhibits BMP-2 induced bone formation
Published in Journal of orthopaedic research (01-06-2008)“…Secreted phosphoprotein 24 kDa (spp24) is a bone matrix protein. It contains a TGF‐β receptor II homology 1 (TRH1) domain. A cyclic, synthetic 19 amino acid…”
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Letters to the editors
Published in Journal of orthopaedic research (01-07-2006)Get full text
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13
Letters to the editors
Published in Journal of orthopaedic research (01-07-2006)Get full text
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14
Letters to the editors
Published in Journal of orthopaedic research (01-07-2006)Get full text
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Protein degradation, molecular chaperones, and osteogenic proteins in bone
Published 01-01-2003“…Bone is the only tissue that is remodeled throughout adult life. As the major load bearing skeletal element, bone is constantly subjected to unusual physical…”
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Dissertation -
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Effects of dietary restriction on appendicular bone in the SENCAR mouse
Published in Metabolism, clinical and experimental (01-04-2001)“…Peptide hormones, cytokines, and growth factors regulate cellular metabolism by stimulating second messenger signal transduction cascades in target tissues. A…”
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Lipids closely associated with bone morphogenetic protein (BMP)--and induced heterotopic bone formation. With preliminary observations of deficiencies in lipid and osteoinduction in lathyrism in rats
Published in Connective tissue research (1997)“…An extensive literature on bone morphogenetic protein (BMP) induced generation and regeneration shows general agreement about one observation. The incidence…”
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