Search Results - "Behera, Ishani"
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1
Structure of the Respiratory Syncytial Virus Polymerase Complex
Published in Cell (19-09-2019)“…Numerous interventions are in clinical development for respiratory syncytial virus (RSV) infection, including small molecules that target viral transcription…”
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Journal Article -
2
Biochemical Evaluation of the Inhibition Properties of Favipiravir and 2'-C-Methyl-Cytidine Triphosphates against Human and Mouse Norovirus RNA Polymerases
Published in Antimicrobial agents and chemotherapy (01-12-2015)“…Norovirus (NoV) is a positive-sense single-stranded RNA virus that causes acute gastroenteritis and is responsible for 200,000 deaths per year worldwide. No…”
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Journal Article -
3
Structure-activity relationship analysis of mitochondrial toxicity caused by antiviral ribonucleoside analogs
Published in Antiviral research (01-07-2017)“…Recent cases of severe toxicity during clinical trials have been associated with antiviral ribonucleoside analogs (e.g. INX-08189 and balapiravir). Some have…”
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Journal Article -
4
Structural and mechanistic insights into the inhibition of respiratory syncytial virus polymerase by a non-nucleoside inhibitor
Published in Communications biology (21-10-2023)“…The respiratory syncytial virus polymerase complex, consisting of the polymerase (L) and phosphoprotein (P), catalyzes nucleotide polymerization, cap addition,…”
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Journal Article -
5
Structure of the Respiratory Syncytial Virus Polymerase Complex
Published in Cell (01-09-2019)“…Numerous interventions are in clinical developmentfor respiratory syncytial virus (RSV) infection,including small molecules that target viral transcrip-tion…”
Get full text
Journal Article -
6
In vivo Evolution of a Trans-splicing Group I Intron Ribozyme
Published 01-01-2018“…The Tetrahymena group I intron was one of the two first catalytic RNAs (ribozymes) to be discovered. Group I introns are sequences that can exist between exons…”
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Dissertation