Search Results - "Beharry, Aruun"

Development of an In Vitro Test Method to Replace an Animal-Based Potency Test for Pertactin Antigen in Multivalent Vaccines by Szeto, Jason, Beharry, Aruun, Chen, Tricia, Zholumbetov, Eric, Daigneault, Emilie, Ming, Marin, Lounsbury, Iain, Eng, Nelson, Thangavadivel, Nemika, Jin, Robbie, Denis-Jacquot, Aurélie, Azad, Bahram Behnam, Li, Meili, Keizner, Diana, Liu, Marcus, Lee, Sophia S F, He, Kai, Gajewska, Beata

“…There is increasing interest to replace animal-based potency assays used routinely to test vaccines, since they are highly variable, are costly, and present…”
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Mechanisms and Delivery of tRNA Therapeutics by Ward, Cian, Beharry, Aruun, Tennakoon, Rasangi, Rozik, Peter, Wilhelm, Sarah D. P., Heinemann, Ilka U., O’Donoghue, Patrick

“…Transfer ribonucleic acid (tRNA) therapeutics will provide personalized and mutation specific medicines to treat human genetic diseases for which no cures…”
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Transfer RNA supplementation rescues HARS deficiency in a humanized yeast model of Charcot-Marie-Tooth disease by Wilhelm, Sarah D P, Kakadia, Jenica H, Beharry, Aruun, Kenana, Rosan, Hoffman, Kyle S, O’Donoghue, Patrick, Heinemann, Ilka U

“…Abstract Aminoacyl-tRNA synthetases are indispensable enzymes in all cells, ensuring the correct pairing of amino acids to their cognate tRNAs to maintain…”
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Histidine supplementation can escalate or rescue HARS deficiency in a Charcot–Marie–Tooth disease model by Qiu, Yi, Kenana, Rosan, Beharry, Aruun, Wilhelm, Sarah D P, Hsu, Sung Yuan, Siu, Victoria M, Duennwald, Martin, Heinemann, Ilka U

“…Abstract Aminoacyl-tRNA synthetases are essential enzymes responsible for charging amino acids onto cognate tRNAs during protein synthesis. In histidyl-tRNA…”
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