Search Results - "Begun, J"

Parallel Gene Expression Differences between Low and High Latitude Populations of Drosophila melanogaster and D. simulans by Zhao, Li, Wit, Janneke, Svetec, Nicolas, Begun, David J

“…Gene expression variation within species is relatively common, however, the role of natural selection in the maintenance of this variation is poorly…”
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Evolution of secondary cell number and position in the Drosophila accessory gland by Takashima, Yoko A., Majane, Alex C., Begun, David J.

“…In animals with internal fertilization, males transfer gametes and seminal fluid during copulation, both of which are required for successful reproduction. In…”
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De novo ORFs in Drosophila are important to organismal fitness and evolved rapidly from previously non-coding sequences by Reinhardt, Josephine A, Wanjiru, Betty M, Brant, Alicia T, Saelao, Perot, Begun, David J, Jones, Corbin D

“…How non-coding DNA gives rise to new protein-coding genes (de novo genes) is not well understood. Recent work has revealed the origins and functions of a few…”
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Review article: consensus statements on therapeutic drug monitoring of anti‐tumour necrosis factor therapy in inflammatory bowel diseases by Mitrev, N., Vande Casteele, N., Seow, C. H., Andrews, J. M., Connor, S. J., Moore, G. T., Barclay, M., Begun, J., Bryant, R., Chan, W., Corte, C., Ghaly, S., Lemberg, D. A., Kariyawasam, V., Lewindon, P., Martin, J., Mountifield, R., Radford‐Smith, G., Slobodian, P., Sparrow, M., Toong, C., Langenberg, D., Ward, M. G., Leong, R. W.

“…Summary Background Therapeutic drug monitoring (TDM) in inflammatory bowel disease (IBD) patients receiving anti‐tumour necrosis factor (TNF) agents can help…”
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Genomics of parallel adaptation at two timescales in Drosophila by Zhao, Li, Begun, David J

“…Two interesting unanswered questions are the extent to which both the broad patterns and genetic details of adaptive divergence are repeatable across species,…”
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Population Genomics of sub-saharan Drosophila melanogaster: African diversity and non-African admixture by Pool, John E, Corbett-Detig, Russell B, Sugino, Ryuichi P, Stevens, Kristian A, Cardeno, Charis M, Crepeau, Marc W, Duchen, Pablo, Emerson, J J, Saelao, Perot, Begun, David J, Langley, Charles H

“…Drosophila melanogaster has played a pivotal role in the development of modern population genetics. However, many basic questions regarding the demographic and…”
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Mindfulness based cognitive therapy for youth with inflammatory bowel disease and depression - Findings from a pilot randomised controlled trial by Ewais, T., Begun, J., Kenny, M., Hay, K., Houldin, Evan, Chuang, Kai-Hisang, Tefay, M., Kisely, S.

“…Mindfulness-based cognitive therapy (MBCT) is a promising adjunctive treatment for adolescents and young adults (AYAs) with Inflammatory Bowel Disease (IBD)…”
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GESA Statement on the timing of elective endoscopic procedures in patients with recent COVID‐19 infection by Lamba, M, Tiwari, N, Remedios, M, Begun, J, Christensen, B, Bollipo, S, Devereaux, B

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The Adaptive Significance of Natural Genetic Variation in the DNA Damage Response of Drosophila melanogaster by Svetec, Nicolas, Cridland, Julie M, Zhao, Li, Begun, David J

“…Despite decades of work, our understanding of the distribution of fitness effects of segregating genetic variants in natural populations remains largely…”
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Strong Selective Sweep Associated with a Transposon Insertion in Drosophila simulans by Schlenke, Todd A., Begun, David J., Kidwell, Margaret G.

“…We know little about several important properties of beneficial mutations, including their mutational origin, their phenotypic effects (e.g., protein structure…”
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Population genomics: whole-genome analysis of polymorphism and divergence in Drosophila simulans by Begun, David J, Holloway, Alisha K, Stevens, Kristian, Hillier, Ladeana W, Poh, Yu-Ping, Hahn, Matthew W, Nista, Phillip M, Jones, Corbin D, Kern, Andrew D, Dewey, Colin N, Pachter, Lior, Myers, Eugene, Langley, Charles H

“…The population genetic perspective is that the processes shaping genomic variation can be revealed only through simultaneous investigation of sequence…”
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US hospital engagement in cross-sector partnerships for population health improvement in socioeconomically distressed counties by Noh, E., Begun, J.W., White, K.M., Potthoff, S.J.

“…This study identifies the internal characteristics of hospitals located in counties with poor socioeconomic conditions that develop collaborative partnerships…”
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Colonic microbiota can promote rapid local improvement of murine colitis by thioguanine independently of T lymphocytes and host metabolism by Oancea, I, Movva, R, Das, I, Aguirre de Cárcer, D, Schreiber, V, Yang, Y, Purdon, A, Harrington, B, Proctor, M, Wang, R, Sheng, Y, Lobb, M, Lourie, R, Ó Cuív, P, Duley, J A, Begun, J, Florin, T H J

“…Mercaptopurine (MP) and pro-drug azathioprine are 'first-line' oral therapies for maintaining remission in IBD. It is believed that their pharmacodynamic…”
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Whole-genome expression plasticity across tropical and temperate Drosophila melanogaster populations from Eastern Australia by Levine, Mia T, Eckert, Melissa L, Begun, David J

“…The genotypic signature of spatially varying selection is ubiquitous across the Drosophila melanogaster genome. Spatially structured adaptive phenotypic…”
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Novel genes derived from noncoding DNA in Drosophila melanogaster are frequently X-linked and exhibit testis-biased expression by Levine, M.T, Jones, C.D, Kern, A.D, Lindfors, H.A, Begun, D.J

“…Descriptions of recently evolved genes suggest several mechanisms of origin including exon shuffling, gene fission/fusion, retrotransposition,…”
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Natural Selection Drives Drosophila Immune System Evolution by Schlenke, Todd A, Begun, David J

“…Evidence from disparate sources suggests that natural selection may often play a role in the evolution of host immune system proteins. However, there have been…”
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Phenotypic coupling of sleep and starvation resistance evolves in D. melanogaster by Sarikaya, Didem P, Cridland, Julie, Tarakji, Adam, Sheehy, Hayley, Davis, Sophia, Kochummen, Ashley, Hatmaker, Ryan, Khan, Nossin, Chiu, Joanna, Begun, David J

“…One hypothesis for the function of sleep is that it serves as a mechanism to conserve energy. Recent studies have suggested that increased sleep can be an…”
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The impact of center accreditation on hematopoietic cell transplantation (HCT) by Marmor, S, Begun, J W, Abraham, J, Virnig, B A

“…There are two voluntary center-accrediting organizations in the USA, the Foundation for the Accreditation of Cellular Therapy (FACT) and core Clinical Trial…”
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Genome of Drosophila suzukii, the spotted wing drosophila by Chiu, Joanna C, Jiang, Xuanting, Zhao, Li, Hamm, Christopher A, Cridland, Julie M, Saelao, Perot, Hamby, Kelly A, Lee, Ernest K, Kwok, Rosanna S, Zhang, Guojie, Zalom, Frank G, Walton, Vaughn M, Begun, David J

“…Drosophila suzukii Matsumura (spotted wing drosophila) has recently become a serious pest of a wide variety of fruit crops in the United States as well as in…”
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Recently Evolved Genes Identified From Drosophila yakuba and D. erecta Accessory Gland Expressed Sequence Tags by Begun, David J, Lindfors, Heather A, Thompson, Melissa E, Holloway, Alisha K

“…The fraction of the genome associated with male reproduction in Drosophila may be unusually dynamic. For example, male reproduction-related genes show…”
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