Search Results - "Beggs, Mark"

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    Delivering the power of discovery in large pharmaceutical organizations by Peakman, Tim, Franks, Steven, White, Colm, Beggs, Mark

    Published in Drug Discovery Today (01-03-2003)
    “…Increasing the output from discovery is currently a major objective for the pharmaceutical industry aimed at reversing recent downward trends in productivity…”
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    Book Review Journal Article
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    Insulin-secreting β-cells possess specific receptors for interleukin-1β by Hammonds, Peter, Beggs, Mark, Beresford, Guy, Espinal, Joseph, Clarke, Jennifer, Mertz, Robert J.

    Published in FEBS letters (12-02-1990)
    “…The effect of the cytokine interleukin-1β on the insulin secretory responsiveness of single β-cells (HIT-T15) was investigated. In the short-term, IL-1β…”
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    Journal Article
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    Automation and Optimization of Protein Expression and Purification on a Novel Robotic Platform by Wollerton, Matthew C., Wales, Richard, Bullock, Jonathan A., Hudson, Ian R., Beggs, Mark

    Published in Journal of Laboratory Automation (01-10-2006)
    “…This article describes a novel robotic system for protein expression and purification. This area has traditionally proved a bottleneck in pharmaceutical…”
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    Journal Article
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    Interleukin-1β inhibits glucokinase activity in clonal HIT-T15 β-cells by Beggs, Mark, Beresford, Guy, Clarke, Jennifer, Mertz, Robert, Espinal, Joseph, Hammonds, Peter

    Published in FEBS letters (16-07-1990)
    “…Interleukin-1β (IL-1β) has been implicated in the pathogenesis of insulin-dependent diabetes mellitus. In the present study we have investigated the effects of…”
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    Journal Article
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