Search Results - "Begani, Priya"

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    Allele-specific silencing of mutant p53 attenuates dominant-negative and gain-of-function activities by Iyer, Swathi V, Parrales, Alejandro, Begani, Priya, Narkar, Akshay, Adhikari, Amit S, Martinez, Luis A, Iwakuma, Tomoo

    Published in Oncotarget (02-02-2016)
    “…Many p53 hotspot mutants not only lose the transcriptional activity, but also show dominant-negative (DN) and oncogenic gain-of-function (GOF) activities…”
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    Journal Article
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    A Family With a Carotid Body Paraganglioma and Thyroid Neoplasias With a New SDHAF2 Germline Variant by Wolf, Katherine I, Jacobs, Michelle F, Mehra, Rohit, Begani, Priya, Davenport, Matthew S, Marentette, Lawrence J, Basura, Gregory J, Hughes, David T, Else, Tobias

    Published in Journal of the Endocrine Society (01-11-2019)
    “…At least 30% of all pheochromocytomas (PCCs)/paragangliomas (PGLs) arise in patients with a germline predisposition syndrome. Variants in succinate…”
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