Search Results - "Beevers, Rebekah"

Synthesis and SAR of aminopyrimidines as novel c-Jun N-terminal kinase (JNK) inhibitors by Alam, Mahbub, Beevers, Rebekah E., Ceska, Tom, Davenport, Richard J., Dickson, Karen M., Fortunato, Mara, Gowers, Lewis, Haughan, Alan F., James, Lynwen A., Jones, Mark W., Kinsella, Natasha, Lowe, Christopher, Meissner, Johannes W.G., Nicolas, Anne-Lise, Perry, Benjamin G., Phillips, David J., Pitt, William R., Platt, Adam, Ratcliffe, Andrew J., Sharpe, Andrew, Tait, Laura J.

“…A series of novel aminopyrimidines is reported which exhibits JNK1 and JNK2 inhibitory activity. The development of a series of novel aminopyrimidines as…”
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Novel indole inhibitors of IMPDH from fragments: Synthesis and initial structure–activity relationships by Beevers, Rebekah E., Buckley, George M., Davies, Natasha, Fraser, Joanne L., Galvin, Francis C., Hannah, Duncan R., Haughan, Alan F., Jenkins, Kerry, Mack, Stephen R., Pitt, William R., Ratcliffe, Andrew J., Richard, Marianna D., Sabin, Verity, Sharpe, Andrew, Williams, Sophie C.

“…The elaboration of previously reported indole fragments as inhibitors of inosine monophosphate dehydrogenase (IMPDH) is described. The synthesis, in vitro…”
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Low molecular weight indole fragments as IMPDH inhibitors by Beevers, Rebekah E., Buckley, George M., Davies, Natasha, Fraser, Joanne L., Galvin, Francis C., Hannah, Duncan R., Haughan, Alan F., Jenkins, Kerry, Mack, Stephen R., Pitt, William R., Ratcliffe, Andrew J., Richard, Marianna D., Sabin, Verity, Sharpe, Andrew, Williams, Sophie C.

“…The study of non-oxazole containing indole fragments as inhibitors of inosine monophosphate dehydrogenase (IMPDH) is described. The synthesis and in vitro…”
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Preparation of kinase-biased compounds in the search for lead inhibitors of kinase targets by Lai, Justine Y.Q., Langston, Steven, Adams, Ruth, Beevers, Rebekah E., Boyce, Richard, Burckhardt, Svenja, Cobb, James, Ferguson, Yvonne, Figueroa, Eva, Grimster, Neil, Henry, Andrew H., Khan, Nawaz, Jenkins, Kerry, Jones, Mark W., Judkins, Robert, Major, Jeremy, Masood, Abid, Nally, James, Payne, Helen, Payne, Lloyd, Raphy, Gilles, Raynham, Tony, Reader, John, Reader, Valérie, Reid, Alison, Ruprah, Parminder, Shaw, Michael, Sore, Hannah, Stirling, Matthew, Talbot, Adam, Taylor, Jess, Thompson, Stephen, Wada, Hiroki, Walker, David

“…This work describes the preparation of approximately 13,000 compounds for rapid identification of hits in high‐throughput screening (HTS). These compounds were…”
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Optimization of a series of multi-isoform PI3 kinase inhibitors by Perry, Benjamin, Beevers, Rebekah, Bennett, Gavin, Buckley, George, Crabbe, Tom, Gowers, Lewis, James, Lynwen, Jenkins, Kerry, Lock, Chris, Sabin, Verity, Wright, Sara

“…Optimization of the cellular and pharmacological activity of a novel series of PI3 kinase inhibitors targeting multiple isoforms is described. Optimization of…”
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Solution and solid-Phase synthesis of potent inhibitors of hepatitis C Virus NS3 proteinase by Beevers, Rebekah, Carr, Maria G, Jones, Philip S, Jordan, Steven, Kay, Paul B, Lazell, Robert C, Raynham, Tony M

“…A versatile route for the synthesis of homochiral α-ketoamide analogues of amino acids is described. Incorporation of this functionality into peptide sequences…”
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