Search Results - "Beetham, J K"
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GENETIC COMPLEMENTATION TO IDENTIFY DNA ELEMENTS THAT INFLUENCE COMPLEMENT RESISTANCE IN LEISHMANIA CHAGASI
Published in The Journal of parasitology (01-10-2005)“…Past studies showed that Leishmania spp. promastigotes exhibit differential sensitivity to complement mediated lysis (CML) during development in vitro and in…”
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Sequence similarity of mammalian epoxide hydrolases to the bacterial haloalkane dehalogenase and other related proteins: Implication for the potential catalytic mechanism of enzymatic epoxide hydrolysis
Published in FEBS letters (07-02-1994)“…Direct comparison of the amino acid sequences of microsomal and soluble epoxide hydrolase superficially indicates that these enzymes are unrelated. Both…”
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cDNA cloning and expression of a soluble epoxide hydrolase from human liver
Published in Archives of biochemistry and biophysics (15-08-1993)“…We report the cloning and expression of a cDNA that encodes a soluble epoxide hydrolase from human liver. The 2101-base clone predicts a 554-residue protein…”
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Cloning and expression of soluble epoxide hydrolase from potato
Published in The Plant journal : for cell and molecular biology (01-08-1994)“…Summary Five cDNAs encoding a putative soluble epoxide hydrolase (sEH) from potato were isolated and characterized. The cDNAs contained open reading frames…”
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Isolation of a putative hydroxyacyl enzyme intermediate of an epoxide hydrolase
Published in Biochemical and biophysical research communications (15-02-1994)“…A putative covalent, alpha-hydroxyacyl intermediate was isolated by the brief exposure of murine soluble epoxide hydrolase to its substrate. The reaction was…”
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Genetic complementation of Leishmania deficient in PSA (GP46) restores their resistance to lysis by complement
Published in Molecular and biochemical parasitology (01-09-2004)Get full text
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Comparison of the post-transcriptional regulation of the mRNAs for the surface proteins PSA (GP46) and MSP (GP63) of Leishmania chagasi
Published in The Journal of biological chemistry (10-05-2002)“…MSP (GP63) and PSA (GP46) are abundant 63- and 46-kDa glycolipid-anchored proteins on the surface of the promastigote form of most Leishmania species. MSP is a…”
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Cress and Potato Soluble Epoxide Hydrolases: Purification, Biochemical Characterization, and Comparison to Mammalian Enzymes
Published in Archives of biochemistry and biophysics (15-06-2000)“…Affinity chromatographic methods were developed for the one-step purification to homogeneity of recombinant soluble epoxide hydrolases (sEHs) from cress and…”
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Cloning, characterization, and genetics of the juvenile hormone esterase gene from Heliothis virescens
Published in Insect biochemistry and molecular biology (01-07-1994)“…The gene for juvenile hormone esterase (JHE) was cloned from Heliothis virescens (Lepidoptera: Noctuidae). A genomic library was constructed from embryonic DNA…”
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Surface glycoprotein PSA (GP46) expression during short- and long-term culture of Leishmania chagasi
Published in Molecular and biochemical parasitology (01-10-2003)“…The mRNAs encoding promastigote surface antigen (PSA) of Leishmania chagasi have previously been shown to increase about 30-fold as in vitro cultured parasites…”
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Molecular and Biochemical Evidence for the Involvement of the Asp-333–His-523 Pair in the Catalytic Mechanism of Soluble Epoxide Hydrolase (∗)
Published in The Journal of biological chemistry (07-04-1995)“…In order to investigate the involvement of amino acids in the catalytic mechanism of the soluble epoxide hydrolase, different mutants of the murine enzyme were…”
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Gene evolution of epoxide hydrolases and recommended nomenclature
Published in DNA and cell biology (01-01-1995)“…We have analyzed amino acid sequence relationships among soluble and microsomal epoxide hydrolases, haloacid dehalogenases, and a haloalkane dehalogenase. The…”
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Glycoprotein 46 mRNA abundance is post-transcriptionally regulated during development of Leishmania chagasi promastigotes to an infectious form
Published in The Journal of biological chemistry (11-07-1997)“…GP46 is an abundant glycoprotein of 46 kDa on the surface of the promastigote form of most Leishmania species. We show that the steady state level of GP46 mRNA…”
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Characterization of an Arabidopsis cDNA for a soluble epoxide hydrolase gene that is inducible by auxin and water stress
Published in The Plant journal : for cell and molecular biology (01-08-1994)“…Summary A cDNA (1122 bp) was isolated from a cDNA library prepared from Arabidopsis thaliana L. that had been subjected to drought stress for 1 h. The…”
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Regulatory sequences and a novel gene in the msp (GP63) gene cluster of Leishmania chagasi
Published in Molecular and biochemical parasitology (15-09-1998)“…The surface protease GP63 of Leishmania chagasi is encoded by a cluster of more than 18 tandem major surface protease ( msp) genes belonging to three classes (…”
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Visualization of a Covalent Intermediate between Microsomal Epoxide Hydrolase, but not Cholesterol Epoxide Hydrolase, and their Substrates
Published in European journal of biochemistry (15-04-1997)“…Mammalian soluble and microsomal epoxide hydrolases have been proposed to belong to the family of αlβ‐hydrolase‐fold enzymes. These enzymes hydrolyse their…”
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Genetic Complementation To Identify DNA Elements That Influence Complement Resistance In Leishmania Chagasi
Published in The Journal of parasitology (01-10-2005)“…Past studies showed that Leishmania spp. promastigotes exhibit differential sensitivity to complement mediated lysis (CML) during development in vitro and in…”
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The enzymatic mechanism of epoxide hydrolysis
Published in Journal of cancer research and clinical oncology (01-01-1995)Get full text
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