Search Results - "Beer, H."

PCSK 9: A Link Between Inflammation and Atherosclerosis by Patriki, Dimitri, Saravi, Seyed Soheil Saeedi, Camici, Giovanni G, Liberale, Luca, Beer, Jürg H

“…Proprotein convertase subtilisin/Kexin 9 (PCSK 9) is revealed to be a key player in lipid metabolism and, therefore, in the development and progression of…”
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Gadolinium Distribution in Cerebrospinal Fluid after Administration of a Gadolinium-based MR Contrast Agent in Humans by Berger, Florian, Kubik-Huch, Rahel A, Niemann, Tilo, Schmid, Hans Ruedi, Poetzsch, Michael, Froehlich, Johannes M, Beer, Jürg H, Thali, Michael J, Kraemer, Thomas

“…Purpose To evaluate whether gadolinium penetrates human cerebrospinal fluid (CSF) after MR imaging (MRI) with a gadolinium-based contrast agent (GBCA)…”
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Apelin-potential therapy for COVID-19? by Saeedi Saravi, Seyed Soheil, Beer, Jürg H.

“…We believe that, in parallel to the attempts for direct blockade of the SARS-CoV-2 penetration into host cell and repurposing drugs, finding new therapeutic…”
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Prospective, multicenter validation of prediction scores for major bleeding in elderly patients with venous thromboembolism by Scherz, N., Méan, M., Limacher, A., Righini, M., Jaeger, K., Beer, H. ‐J., Frauchiger, B., Osterwalder, J., Kucher, N., Matter, C. M., Banyai, M., Angelillo‐Scherrer, A., Lämmle, B., Husmann, M., Egloff, M., Aschwanden, M., Bounameaux, H., Cornuz, J., Rodondi, N., Aujesky, D.

“…Summary Background The Outpatient Bleeding Risk Index (OBRI) and the Kuijer, RIETE and Kearon scores are clinical prognostic scores for bleeding in patients…”
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Recognition of child maltreatment in emergency departments in Europe: Should we do better? by Hoedeman, F, Puiman, P J, Smits, A W, Dekker, M I, Diderich-Lolkes de Beer, H, Laribi, S, Lauwaert, D, Oostenbrink, R, Parri, N, García-Castrillo Riesgo, L, Moll, H A

“…To evaluate the different policies to recognize child maltreatment in emergency departments (EDs) in Europe in order to define areas of improvement. A survey…”
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Sirtuin 5 as a novel target to blunt blood–brain barrier damage induced by cerebral ischemia/reperfusion injury by Diaz-Cañestro, Candela, Merlini, Mario, Bonetti, Nicole R., Liberale, Luca, Wüst, Patricia, Briand-Schumacher, Sylvie, Klohs, Jan, Costantino, Sara, Miranda, Melroy, Schoedon-Geiser, Gabriele, Kullak-Ublick, Gerd A., Akhmedov, Alexander, Paneni, Francesco, Beer, Jürg H., Lüscher, Thomas F., Camici, Giovanni G.

“…In acute ischemic stroke (AIS) patients, impaired blood–brain barrier (BBB) integrity is associated with hemorrhagic transformation and worsened outcome. Yet,…”
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Antibiotic use associated with VTE and its implications: a new trigger for thromboprophylaxis and for reclassification of some unprovoked to provoked VTE's? by Beer, Jürg H.

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Health-related quality of life in patients with atrial fibrillation: The role of symptoms, comorbidities, and the type of atrial fibrillation by Witassek, Fabienne, Springer, Anne, Adam, Luise, Aeschbacher, Stefanie, Beer, Jürg H, Blum, Steffen, Bonati, Leo H, Conen, David, Kobza, Richard, Kühne, Michael, Moschovitis, Giorgio, Osswald, Stefan, Rodondi, Nicolas, Sticherling, Christian, Szucs, Thomas, Schwenkglenks, Matthias

“…This study aimed to analyse health related quality of life (HRQoL) for patients with different atrial fibrillation (AF) types and to identify patient…”
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Circulating extracellular DNA is an independent predictor of mortality in elderly patients with venous thromboembolism by Jiménez-Alcázar, Miguel, Limacher, Andreas, Panda, Rachita, Méan, Marie, Bitterling, Josephine, Peine, Sven, Renné, Thomas, Beer, Jürg H, Aujesky, Drahomir, Lämmle, Bernhard, Fuchs, Tobias A

“…Venous thromboembolism (VTE) is a major cause of morbidity and mortality in elderly patients. Extracellular DNA is a pro-inflammatory and pro-thrombotic…”
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Endothelial SIRT6 blunts stroke size and neurological deficit by preserving blood–brain barrier integrity: a translational study by Liberale, Luca, Gaul, Daniel S, Akhmedov, Alexander, Bonetti, Nicole R, Nageswaran, Vanasa, Costantino, Sarah, Pahla, Jürgen, Weber, Julien, Fehr, Vera, Vdovenko, Daria, Semerano, Aurora, Giacalone, Giacomo, Kullak-Ublick, Gerd A, Sessa, Maria, Eriksson, Urs, Paneni, Francesco, Ruschitzka, Frank, Montecucco, Fabrizio, Beer, Jürg H, Lüscher, Thomas F, Matter, Christian M, Camici, Giovanni G

“…Abstract Aims Aging is an established risk factor for stroke; genes regulating longevity are implicated in the pathogenesis of ischaemic stroke where to date,…”
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Multicentre validation of the Geneva Risk Score for hospitalised medical patients at risk of venous thromboembolism. Explicit ASsessment of Thromboembolic RIsk and Prophylaxis for Medical PATients in SwitzErland (ESTIMATE) by Nendaz, M, Spirk, D, Kucher, N, Aujesky, D, Hayoz, D, Beer, J H, Husmann, M, Frauchiger, B, Korte, W, Wuillemin, W A, Jäger, K, Righini, M, Bounameaux, H

“…There is a need to validate risk assessment tools for hospitalised medical patients at risk of venous thromboembolism (VTE). We investigated whether a…”
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Silent brain infarcts impact on cognitive function in atrial fibrillation by Kühne, Michael, Krisai, Philipp, Coslovsky, Michael, Rodondi, Nicolas, Müller, Andreas, Beer, Jürg H, Ammann, Peter, Auricchio, Angelo, Moschovitis, Giorgio, Hayoz, Daniel, Kobza, Richard, Shah, Dipen, Stephan, Frank Peter, Schläpfer, Jürg, Di Valentino, Marcello, Aeschbacher, Stefanie, Ehret, Georg, Eken, Ceylan, Monsch, Andreas, Roten, Laurent, Schwenkglenks, Matthias, Springer, Anne, Sticherling, Christian, Reichlin, Tobias, Zuern, Christine S, Meyre, Pascal B, Blum, Steffen, Sinnecker, Tim, Würfel, Jens, Bonati, Leo H., Conen, David, Osswald, Stefan

“…Abstract Aims We aimed to investigate the association of clinically overt and silent brain lesions with cognitive function in atrial fibrillation (AF)…”
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Amotosalen/ultraviolet A pathogen inactivation technology reduces platelet activatability, induces apoptosis and accelerates clearance by Stivala, Simona, Gobbato, Sara, Infanti, Laura, Reiner, Martin F, Bonetti, Nicole, Meyer, Sara C, Camici, Giovanni G, Lüscher, Thomas F, Buser, Andreas, Beer, Jürg H

“…Amotosalen and ultraviolet A (UVA) photochemical-based pathogen reduction using the Intercept™ Blood System (IBS) is an effective and established technology…”
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Carbamylated Low-Density Lipoproteins Induce a Prothrombotic State Via LOX-1: Impact on Arterial Thrombus Formation In Vivo by Holy, Erik W, Akhmedov, Alexander, Speer, Thimoteus, Camici, Giovanni G, Zewinger, Stephen, Bonetti, Nicole, Beer, Jürg H, Lüscher, Thomas F, Tanner, Felix C

“…Carbamylation alters low-density lipoprotein (LDL) structure and is thought to promote vascular inflammation and dysfunction in patients with chronic kidney…”
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The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1β processing by Papin, S, Cuenin, S, Agostini, L, Martinon, F, Werner, S, Beer, H-D, Grütter, C, Grütter, M, Tschopp, J

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Glycoprotein Ib clustering in platelets can be inhibited by α-linolenic acid as revealed by cryo-electron tomography by Stivala, Simona, Sorrentino, Simona, Gobbato, Sara, Bonetti, Nicole R, Camici, Giovanni G, Lüscher, Thomas F, Medalia, Ohad, Beer, Jürg H

“…Platelet adhesion to the sub-endothelial matrix and damaged endothelium occurs through a multi-step process mediated in the initial phase by glycoprotein Ib…”
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Dietary alpha‐linolenic acid reduces platelet activation and collagen‐mediated cell adhesion in sickle cell disease mice by Stivala, Simona, Gobbato, Sara, Bonetti, Nicole, Camici, Giovanni G., Lüscher, Thomas F., Beer, Jürg H.

“…Background Sickle cell disease (SCD) is a genetic hemoglobinopathy associated with high morbidity and mortality. The primary cause of hospitalization in SCD is…”
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AP-1 (Activated Protein-1) Transcription Factor JunD Regulates Ischemia/Reperfusion Brain Damage via IL-1β (Interleukin-1β) by Diaz-Cañestro, Candela, Reiner, Martin F, Bonetti, Nicole R, Liberale, Luca, Merlini, Mario, Wüst, Patricia, Amstalden, Heidi, Briand-Schumacher, Sylvie, Semerano, Aurora, Giacalone, Giacomo, Sessa, Maria, Beer, Jürg H, Akhmedov, Alexander, Lüscher, Thomas F, Camici, Giovanni G

“…BACKGROUND AND PURPOSE—Inflammation is a major pathogenic component of ischemia/reperfusion brain injury, and as such, interventions aimed at inhibiting…”
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Bleeding and ischaemic events after first bleed in anticoagulated atrial fibrillation patients: risk and timing by Meyre, Pascal B, Blum, Steffen, Hennings, Elisa, Aeschbacher, Stefanie, Reichlin, Tobias, Rodondi, Nicolas, Beer, Jürg H, Stauber, Annina, Müller, Andreas, Sinnecker, Tim, Moutzouri, Elisavet, Paladini, Rebecca E, Moschovitis, Giorgio, Conte, Giulio, Auricchio, Angelo, Ramadani, Alexandra, Schwenkglenks, Matthias, Bonati, Leo H, Kühne, Michael, Osswald, Stefan, Conen, David

“…To determine the risk of subsequent adverse clinical outcomes in anticoagulated patients with atrial fibrillation (AF) who experienced a new bleeding event…”
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JCAD promotes arterial thrombosis through PI3K/Akt modulation: a translational study by Liberale, Luca, Puspitasari, Yustina M, Ministrini, Stefano, Akhmedov, Alexander, Kraler, Simon, Bonetti, Nicole R, Beer, Georgia, Vukolic, Ana, Bongiovanni, Dario, Han, Jiaying, Kirmes, Kilian, Bernlochner, Isabell, Pelisek, Jaroslav, Beer, Jürg H, Jin, Zheng-Gen, Pedicino, Daniela, Liuzzo, Giovanna, Stellos, Konstantinos, Montecucco, Fabrizio, Crea, Filippo, Lüscher, Thomas F, Camici, Giovanni G

“…Abstract Aims Variants of the junctional cadherin 5 associated (JCAD) locus associate with acute coronary syndromes. JCAD promotes experimental atherosclerosis…”
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