Search Results - "Beer, Ambros J"
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Diffusion-weighted imaging outside the brain: Consensus statement from an ISMRM-sponsored workshop
Published in Journal of magnetic resonance imaging (01-09-2016)“…The significant advances in magnetic resonance imaging (MRI) hardware and software, sequence design, and postprocessing methods have made diffusion‐weighted…”
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PET/MR imaging in the detection and characterization of pulmonary lesions: technical and diagnostic evaluation in comparison to PET/CT
Published in Journal of Nuclear Medicine (01-05-2014)“…Fully integrated PET/MR imaging holds great promise as a novel hybrid imaging modality in oncology and might offer advantages to PET/CT in many instances,…”
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Population-based model selection for an accurate estimation of time-integrated activity using non-linear mixed-effects modelling
Published in Zeitschrift für medizinische Physik (01-08-2024)“…Personalized treatment planning in Molecular Radiotherapy (MRT) with accurately determining the absorbed dose is highly desirable. The absorbed dose is…”
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PET/CT Imaging of Integrin αvβ3 Expression in Human Carotid Atherosclerosis
Published in JACC. Cardiovascular imaging (01-02-2014)“…Objectives The goal of this study was to evaluate the feasibility of [18 F]Galacto-RGD positron emission tomography (PET)/computed tomography (CT) imaging of…”
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In vivo molecular imaging of chemokine receptor CXCR4 expression in patients with advanced multiple myeloma
Published in EMBO molecular medicine (01-04-2015)“…CXCR4 is a G‐protein‐coupled receptor that mediates recruitment of blood cells toward its ligand SDF‐1. In cancer, high CXCR4 expression is frequently…”
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Single-time-point estimation of absorbed doses in PRRT using a non-linear mixed-effects model
Published in Zeitschrift für medizinische Physik (01-02-2023)“…Estimation of accurate time-integrated activity coefficients (TIACs) and radiation absorbed doses (ADs) is desirable for treatment planning in peptide-receptor…”
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Personalized [177Lu]Lutetium-PSMA Therapy for Patients with Pre-Treated Castration-Resistant Prostate Cancer: A Single Institution Experience from a Comprehensive Cancer Centre
Published in Cancers (16-06-2023)“…Castration resistant prostate cancer (CRPC) is characterized by an aggressive biological behavior with a relatively short survival time, especially in…”
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Workflow and scan protocol considerations for integrated whole-body PET/MRI in oncology
Published in Journal of Nuclear Medicine (01-09-2012)“…Integrated PET/MRI systems open exciting possibilities for clinical and research applications. However, compared with PET/CT, PET/MRI is a complex technique…”
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Single-time-point dosimetry using model selection and nonlinear mixed-effects modelling: a proof of concept
Published in EJNMMI physics (10-02-2023)“…Purpose This project aims to develop and evaluate a method for accurately determining time-integrated activities (TIAs) in single-time-point (STP) dosimetry…”
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Value of a Dixon-based MR/PET attenuation correction sequence for the localization and evaluation of PET-positive lesions
Published in European journal of nuclear medicine and molecular imaging (01-09-2011)“…Purpose In this study, the potential contribution of Dixon-based MR imaging with a rapid low-resolution breath-hold sequence, which is a technique used for…”
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SARS-CoV-2 infection and the brain: direct evidence for brain changes in milder cases
Published in Signal transduction and targeted therapy (11-07-2022)Get full text
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Radionuclide and hybrid imaging of recurrent prostate cancer
Published in The lancet oncology (01-02-2011)“…Summary Prostate cancer is one of the most common cancers in men, leading to substantial morbidity and mortality. After definitive therapy with surgery or…”
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[18F]Galacto-RGD Positron Emission Tomography for Imaging of αvβ3 Expression on the Neovasculature in Patients with Squamous Cell Carcinoma of the Head and Neck
Published in Clinical cancer research (15-11-2007)“…Purpose: [ 18 F]Galacto-RGD has been developed for positron emission tomography (PET)–imaging of αvβ3 expression, a receptor involved in angiogenesis and…”
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Influence of sampling schedules on [177Lu]Lu-PSMA dosimetry
Published in EJNMMI physics (17-06-2020)“…Background Individualized dosimetry is recommended for [ 177 Lu]Lu-PSMA radioligand therapy (RLT) which is resource-intensive and protocols are often not…”
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Evaluation of the EPR Effect in the CAM-Model by Molecular Imaging with MRI and PET Using 89Zr-Labeled HSA
Published in Cancers (09-02-2023)“…Mouse models are commonly used to study the biodistribution of novel radioligands, but alternative models corresponding to the 3Rs principles, such as the…”
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Quantitative analysis of regional distribution of tau pathology with 11C-PBB3-PET in a clinical setting
Published in PloS one (2022)“…The recent developments of tau-positron emission tomography (tau-PET) enable in vivo assessment of neuropathological tau aggregates. Among the tau-specific…”
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A Physiologically Based Pharmacokinetic Model for In Vivo Alpha Particle Generators Targeting Neuroendocrine Tumors in Mice
Published in Pharmaceutics (10-12-2021)“…In vivo alpha particle generators have great potential for the treatment of neuroendocrine tumors in alpha-emitter-based peptide receptor radionuclide therapy…”
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PET-MRI Fusion in Head-and-Neck Oncology: Current Status and Implications for Hybrid PET/MRI
Published in Journal of oral and maxillofacial surgery (01-02-2012)“…Purpose To review the current status and clinical effect of PET-MRI image fusion in the staging of head-and-neck cancer and to show its implications for…”
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Comparison of PSMA-TO-1 and PSMA-617 labeled with gallium-68, lutetium-177 and actinium-225
Published in EJNMMI research (01-10-2022)“…Background PSMA-TO-1 (“Tumor-Optimized-1”) is a novel PSMA ligand with longer circulation time than PSMA-617. We compared the biodistribution in subcutaneous…”
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Short-Interval, Low-Dose Peptide Receptor Radionuclide Therapy in Combination with PD-1 Checkpoint Immunotherapy Induces Remission in Immunocompromised Patients with Metastatic Merkel Cell Carcinoma
Published in Pharmaceutics (14-07-2022)“…Merkel cell carcinoma (MCC) is a neuroendocrine skin cancer of the elderly, with high metastatic potential and poor prognosis. In particular, the primary…”
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