Search Results - "Beenhakker, Niels"

Transgenic fluorescent Plasmodium cynomolgi liver stages enable live imaging and purification of Malaria hypnozoite-forms by Voorberg-van der Wel, Annemarie, Zeeman, Anne-Marie, van Amsterdam, Sandra M, van den Berg, Alexander, Klooster, Els J, Iwanaga, Shiroh, Janse, Chris J, van Gemert, Geert-Jan, Sauerwein, Robert, Beenhakker, Niels, Koopman, Gerrit, Thomas, Alan W, Kocken, Clemens H M

“…A major challenge for strategies to combat the human malaria parasite Plasmodium vivax is the presence of hypnozoites in the liver. These dormant forms can…”
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Differential CD4+ versus CD8+ T-Cell Responses Elicited by Different Poxvirus-Based Human Immunodeficiency Virus Type 1 Vaccine Candidates Provide Comparable Efficacies in Primates by MOOIJ, Petra, BALLA-JHAGJHOORSINGH, Sunita S, GOMEZ, Carmen E, NAJERA, José L, JIMENEZ, Victoria, ESTEBAN, Mariano, HEENEY, Jonathan L, KOOPMAN, Gerrit, BEENHAKKER, Niels, VAN HAAFTEN, Patricia, BAAK, Ilona, NIEUWENHUIS, Ivonne G, KONDOVA, Ivanela, WAGNER, Ralf, WOLF, Hans

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Experimental infection of rhesus macaques and common marmosets with a European strain of West Nile virus by Verstrepen, Babs E, Fagrouch, Zahra, van Heteren, Melanie, Buitendijk, Hester, Haaksma, Tom, Beenhakker, Niels, Palù, Giorgio, Richner, Justin M, Diamond, Michael S, Bogers, Willy M, Barzon, Luisa, Chabierski, Stefan, Ulbert, Sebastian, Kondova, Ivanela, Verschoor, Ernst J

“…West Nile virus (WNV) is a mosquito-borne flavivirus that infects humans and other mammals. In some cases WNV causes severe neurological disease. During recent…”
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Aerosol immunization with NYVAC and MVA vectored vaccines is safe, simple, and immunogenic by Corbett, Max, Bogers, Willy M, Heeney, Jonathan L, Gerber, Stefan, Genin, Christian, Didierlaurent, Arnaud, Oostermeijer, Herman, Dubbes, Rob, Braskamp, Gerco, Lerondel, Stéphanie, Gomez, Carmen E, Esteban, Mariano, Wagner, Ralf, Kondova, Ivanella, Mooij, Petra, Balla-Jhagjhoorsingh, Sunita, Beenhakker, Niels, Koopman, Gerrit, van der Burg, Sjoerd, Kraehenbuhl, Jean-Pierre, Le Pape, Alain

“…Each year, approximately five million people die worldwide from putatively vaccine-preventable mucosally transmitted diseases. With respect to mass vaccination…”
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Comparison of Human and Rhesus Macaque T-Cell Responses Elicited by Boosting with NYVAC Encoding Human Immunodeficiency Virus Type 1 Clade C Immunogens by Mooij, Petra, Balla-Jhagjhoorsingh, Sunita S, Beenhakker, Niels, van Haaften, Patricia, Baak, Ilona, Nieuwenhuis, Ivonne G, Heidari, Shirin, Wolf, Hans, Frachette, Marie-Joelle, Bieler, Kurt, Sheppard, Neil, Harari, Alexandre, Bart, Pierre-Alexandre, Liljeström, Peter, Wagner, Ralf, Pantaleo, Giuseppe, Heeney, Jonathan L

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Increased, Durable B-Cell and ADCC Responses Associated with T-Helper Cell Responses to HIV-1 Envelope in Macaques Vaccinated with gp140 Occluded at the CD4 Receptor Binding Site by Bogers, Willy M J M, Barnett, Susan W, Oostermeijer, Herman, Nieuwenhuis, Ivonne G, Beenhakker, Niels, Mortier, Daniella, Mooij, Petra, Koopman, Gerrit, Remarque, Edmund, Martin, Gregoire, Lai, Rachel Pei-Jen, Dey, Antu K, Sun, Yide, Burke, Brian, Ferrari, Guido, Montefiori, David, Martin, Loic, Davis, David, Srivastava, Indresh, Heeney, Jonathan L

“…Strategies are needed to improve the immunogenicity of HIV-1 envelope (Env) antigens (Ag) for more long-lived, efficacious HIV-1 vaccine-induced B-cell…”
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Synthetic long peptide booster immunization in rhesus macaques primed with replication-competent NYVAC-C-KC induces a balanced CD4/CD8 T-cell and antibody response against the conserved regions of HIV-1 by Mooij, Petra, Koopman, Gerrit, Drijfhout, Jan Wouter, Nieuwenhuis, Ivonne G, Beenhakker, Niels, Koestler, Josef, Bogers, Willy M J M, Wagner, Ralf, Esteban, Mariano, Pantaleo, Giuseppe, Heeney, Jonathan L, Jacobs, Bertram L, Melief, Cornelis J M

“…The Thai trial (RV144) indicates that a prime-boost vaccine combination that induces both T-cell and antibody responses may be desirable for an effective HIV…”
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DNA/long peptide vaccination against conserved regions of SIV induces partial protection against SIVmac251 challenge by KOOPMAN, Gerrit, BEENHAKKER, Niels, BONTROP, Ronald E, WAGNER, Ralf, BOGERS, Willy M. J. M, MELIEF, Cornelis J. M, NIEUWENHUIS, Ivonne, DOXIADIS, Gaby, MOOIJ, Petra, DRIJFHOUT, Jan W, KOESTLER, Josef, HANKE, Tomas, FAGROUCH, Zahra, VERSCHOOR, Ernst J

“…We recently developed a HIVconsv vaccine strategy, consisting of combined conserved regions of HIV-1, to adequately cover viral diversity. To evaluate efficacy…”
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Targeted delivery of CpG ODN to CD32 on human and monkey plasmacytoid dendritic cells augments IFN[alpha] secretion by Tel, Jurjen, Beenhakker, Niels, Koopman, Gerrit, Hart, Bert't, Mudde, Geert C, de Vries, IJolanda M

“…Atopic diseases are characterized by the presence of Th2 cells. Recent studies, in mice and man, demonstrated that allergen-specific Th2 responses can be…”
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Experimental Infection of Rhesus Macaques and Common Marmosets with a European Strain of West Nile Virus: e2797 by Verstrepen, Babs E, Fagrouch, Zahra, Heteren, Melanie van, Buitendijk, Hester, Haaksma, Tom, Beenhakker, Niels, Palù, Giorgio, Richner, Justin M, Diamond, Michael S, Bogers, Willy M, Barzon, Luisa, Chabierski, Stefan, Ulbert, Sebastian, Kondova, Ivanela, Verschoor, Ernst J

“…West Nile virus (WNV) is a mosquito-borne flavivirus that infects humans and other mammals. In some cases WNV causes severe neurological disease. During recent…”
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Targeted delivery of CpG ODN to CD32 on human and monkey plasmacytoid dendritic cells augments IFNα secretion by Tel, Jurjen, Beenhakker, Niels, Koopman, Gerrit, Hart, Bert’t, Mudde, Geert C, de Vries, I. Jolanda M

“…Abstract Atopic diseases are characterized by the presence of Th2 cells. Recent studies, in mice and man, demonstrated that allergen-specific Th2 responses can…”
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Immunization with apoptotic pseudovirus transduced cells induces both cellular and humoral responses: A proof of concept study in macaques by Koopman, Gerrit, Beenhakker, Niels, Hofman, Sam, Walther-Jallow, Lilian, Mäkitalo, Barbro, Mooij, Petra, Anderson, Jan, Verschoor, Ernst, Bogers, Willy M.J, Heeney, Jonathan L, Spetz, Anna-Lena

“…Highlights ► We measure responses after immunization of apoptotic T-cells carrying defective SIV. ► Local transient skin reactions appear at injection site. ►…”
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No difference in Gag and Env immune-response profiles between vaccinated and non-vaccinated rhesus macaques that control immunodeficiency virus replication by NIEUWENHUIS, Ivonne, BEENHAKKER, Niels, BOGERS, Willy M. J. M, OTTING, Nel, BONTROP, Ronald E, DUBOIS, Patrice, MOOIJ, Petra, HEENEY, Jonathan L, KOOPMAN, Gerrit

“…Recent advances in human immunodeficiency virus (HIV) vaccine design have resulted in induction of strong CD4 T-cell proliferative and polyfunctional cytokine…”
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Differential CD4 super(+) versus CD8 super(+) T-Cell Responses Elicited by Different Poxvirus-Based Human Immunodeficiency Virus Type 1 Vaccine Candidates Provide Comparable Efficacies in Primates by Mooij, Petra, Balla-Jhagjhoorsingh, Sunita S, Koopman, Gerrit, Beenhakker, Niels, van Haaften, Patricia, Baak, Ilona, Nieuwenhuis, Ivonne G, Kondova, Ivanela, Wagner, Ralf, Wolf, Hans, Gomez, Carmen E, Najera, Jose L, Jimenez, Victoria, Esteban, Mariano, Heeney, Jonathan L

“…Poxvirus vectors have proven to be highly effective for boosting immune responses in diverse vaccine settings. Recent reports reveal marked differences in the…”
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Comparison of Human and Rhesus Macaque T-Cell Responses Elicited by Boosting with NYVAC Encoding Human Immunodeficiency Virus Type 1 Clade C Immunogens by MOOIJ, Petra, BALLA-JHAGJHOORSINGH, Sunita S, SHEPPARD, Neil, HARARI, Alexandre, BART, Pierre-Alexandre, LILJESTRÖM, Peter, WAGNER, Ralf, PANTALEO, Giuseppe, HEENEY, Jonathan L, BEENHAKKER, Niels, VAN HAAFTEN, Patricia, BAAK, Ilona, NIEUWENHUIS, Ivonne G, HEIDARI, Shirin, WOLF, Hans, FRACHETTE, Marie-Joelle, BIELER, Kurt

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